Current Trends in Green Solvents: Biocompatible Ionic Liquids

Biocompatible Ionic Liquids (Bio-ILs) are a new class of ILs that are task-specifically designed to derive from naturally occurring compounds and/or derivatives thereof, as well as molecules well known for their biocompatibility (e.g., active pharmaceutical ingredients or non-toxic bioactive compounds) in terms of sustainability and biocompatibility. Owing to their remarkable physicochemical properties that can be tailor made to comply with the requirements of each application, Bio-ILs have emerged as novel, efficient and green technology, appropriate for a vast variety of scientific fields. Herein, this review describes the state-of-the-art scientific research regarding the synthesis, characterization and applications of Bio-ILs reported in the literature for the period between 2020 and 2022.

[1]  Xiaocong Liang,et al.  Controllable recovery and regeneration of bio-derived ionic liquid choline acetate for biomass processing via bipolar membrane electrodialysis-based methodology , 2022, Separation and Purification Technology.

[2]  J. Araújo,et al.  Human Cytotoxicity, Hemolytic Activity, Anti-Inflammatory Activity and Aqueous Solubility of Ibuprofen-Based Ionic Liquids , 2022, Sustainable Chemistry.

[3]  C. Porter,et al.  Biocompatible Cationic Lipoamino Acids as Counterions for Oral Administration of API-Ionic Liquids , 2022, Pharmaceutical Research.

[4]  A. Avachat,et al.  Choline-Amino Acid-Derived Bio-ionic Liquids for Solubility Enhancement of Zafirlukast , 2022, AAPS PharmSciTech.

[5]  Ismael Díaz,et al.  Assessment of bio-ionic liquids as promising solvents in industrial separation processes: Computational screening using COSMO-RS method , 2022, Fluid Phase Equilibria.

[6]  T. Lodge,et al.  Improved nanoformulation and bio-functionalization of linear-dendritic block copolymers with biocompatible ionic liquids. , 2022, Nanoscale.

[7]  Wei Wu,et al.  Converting Tretinoin into Ionic Liquids for Improving Aqueous Solubility and Permeability across Skin , 2022, Pharmaceutical Research.

[8]  Tianxiang Yin,et al.  Ionic liquids as effective additives to enhance the solubility and permeation for puerarin and ferulic acid , 2022, RSC advances.

[9]  Špela Zupančič,et al.  Preparation and characterization of innovative electrospun nanofibers loaded with pharmaceutically applicable ionic liquids. , 2022, International journal of pharmaceutics.

[10]  Peng Zhang,et al.  Applications of Choline-based Ionic Liquids in Drug Delivery. , 2021, International journal of pharmaceutics.

[11]  Fusheng Liu,et al.  Biocompatible anions-derived ionic liquids a sustainable media for CO2 conversion into quinazoline-2,4(1H,3H)-diones under additive-free conditions , 2021, Journal of CO2 Utilization.

[12]  I. Banerjee,et al.  Exploring the Interactions of Ionic Liquids with Bio-Organic Amphiphiles Using Computational Approaches , 2021, ACS omega.

[13]  S. Bocchini,et al.  Efficient and reversible CO2 capture in bio-based ionic liquids solutions , 2021, Journal of CO2 Utilization.

[14]  S. Ventura,et al.  Synthesis of Purine-Based Ionic Liquids and Their Applications , 2021, Molecules.

[15]  M. Moniruzzaman,et al.  Amino Acid Ester based Phenolic Ionic Liquids as a Potential Solvent for the Bioactive Compound Luteolin: Synthesis, Characterization, and Food Preservation Activity , 2021, Journal of Molecular Liquids.

[16]  Gaoshang Wang,et al.  Soybean oil-based monoacylglycerol synthesis using bio-compatible amino acid ionic liquid as a catalyst at low temperature , 2021 .

[17]  V. Ananikov,et al.  Metal nanoparticles in ionic liquids: Synthesis and catalytic applications , 2021 .

[18]  K. Prasad,et al.  Syntheses and characterization of few bio-ionic liquids comprising of cholinium cation and plant derived carboxylic acids as anions , 2021, Journal of the Indian Chemical Society.

[19]  H. Al‐Lohedan,et al.  Novel Bio-Based Amphiphilic Ionic Liquids for the Efficient Demulsification of Heavy Crude Oil Emulsions , 2021, Molecules.

[20]  B. Simmons,et al.  Towards understanding of delignification of grassy and woody biomass in cholinium-based ionic liquids , 2021, Green Chemistry.

[21]  M. Simões,et al.  Choline-based ionic liquids for planktonic and biofilm growth control of Bacillus cereus and Pseudomonas fluorescens , 2021, Journal of Molecular Liquids.

[22]  M. Wilkins,et al.  Exploring lignin depolymerization by a bi-enzyme system containing aryl alcohol oxidase and lignin peroxidase in aqueous biocompatible ionic liquids. , 2021, Bioresource technology.

[23]  S. Mitragotri,et al.  Recent Advances in Ionic Liquids in Biomedicine , 2021, Advanced science.

[24]  J. Hallett,et al.  Production of Food-Grade Glucose from Rice and Wheat Residues Using a Biocompatible Ionic Liquid , 2021 .

[25]  K. R. Patil,et al.  Investigations of solute–solvent interactions in aqueous solutions of amino acids ionic liquids having the common nitrate as anion at different temperatures , 2021 .

[26]  Hemant K. Kashyap,et al.  Unique and generic structural features of cholinium amino acid-based biocompatible ionic liquids. , 2021, Physical chemistry chemical physics : PCCP.

[27]  J. Coutinho,et al.  Cholinium-based Ionic Liquids as Bioinspired Hydrotropes to Tackle Solubility Challenges in Drug Formulation. , 2021, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[28]  J. Pernak,et al.  L‐Carnitine‐Based Bio‐Ionic Liquids as Antioxidants , 2021 .

[29]  F. Cesare Marincola,et al.  Cholinium-Based Ionic Liquids from Hydroxycinnamic Acids as New Promising Bioactive Agents: A Combined Experimental and Theoretical Investigation , 2021 .

[30]  A. Taubert,et al.  Metal Sulfide Nanoparticle Synthesis with Ionic Liquids – State of the Art and Future Perspectives , 2021, ChemistryOpen.

[31]  A. Das,et al.  Bio-ionic liquid promoted selective coagulation of κ-carrageenan from Kappaphycus alvarezii extract , 2021 .

[32]  E. Bodo,et al.  Cholinium amino acid-based ionic liquids , 2021, Biophysical Reviews.

[33]  A. Kasar,et al.  Tribological performance of environmental friendly ionic liquids for high-temperature applications , 2021 .

[34]  Y. Ikeda,et al.  Structural Evaluation of the Choline and Geranic Acid/Water Complex by SAXS and NMR Analyses. , 2021, ACS Biomaterials Science & Engineering.

[35]  A. Mudring,et al.  Synthesis of luminescent semiconductor nanoparticles in ionic liquids –the importance of the ionic liquid in the formation of quantum dots , 2021 .

[36]  J. Ko,et al.  Clinical translation of choline and geranic acid deep eutectic solvent , 2020, Bioengineering & translational medicine.

[37]  Arturo Sánchez,et al.  One-pot ethanol production under optimized pretreatment conditions using agave bagasse at high solids loading with low-cost biocompatible protic ionic liquid , 2021, Green Chemistry.

[38]  R. Sheldon.  Biocatalysis in Ionic Liquids: State-of-the-Union , 2021, Green Chemistry.

[39]  G. Garg,et al.  Palladium Nanoparticles in Glycerol/Ionic Liquid/Carbon Dioxide Medium as Hydrogenation Catalysts , 2020 .

[40]  M. Moniruzzaman,et al.  Biocompatible ionic liquids and their applications in pharmaceutics , 2020 .

[41]  C. Pomelli,et al.  Exploiting Deep Eutectic Solvents and Ionic Liquids for the Valorization of Chestnut Shell Waste , 2020 .

[42]  M. Guardia,et al.  Deep eutectic solvents vs ionic liquids: Similarities and differences , 2020 .

[43]  M. Moniruzzaman,et al.  Lipid based biocompatible ionic liquids: synthesis, characterization and biocompatibility evaluation. , 2020, Chemical communications.

[44]  A. Detsi,et al.  Green synthesis of bis-(β-dicarbonyl)-methane derivatives and biological evaluation as putative anticandidial agents , 2020 .

[45]  R. Saxena,et al.  Guanidine based amino acid derived task specific ionic liquids as noncorrosive lubricant additives for tribological performance , 2020 .

[46]  I. Marrucho,et al.  Antimicrobial Activities of Highly Bioavailable Organic Salts and Ionic Liquids from Fluoroquinolones , 2020, Pharmaceutics.

[47]  M. Guzik,et al.  Combining amino acids and carbohydrates into readily biodegradable, task specific ionic liquids , 2020, RSC advances.

[48]  S. Fourmentin,et al.  Air pollution: new bio-based ionic liquids absorb both hydrophobic and hydrophilic volatile organic compounds with high efficiency , 2020, Environmental Chemistry Letters.

[49]  G. Garg,et al.  Palladium nanoparticles stabilized by novel choline-based ionic liquids in glycerol applied in hydrogenation reactions , 2020 .

[50]  A. Kesavan,et al.  Antimicrobial Colloidal Complexes of Lysozyme with Bio-based Surface Active Ionic Liquids in Aqueous Medium. , 2020, The journal of physical chemistry. B.

[51]  P. Drid,et al.  Physicochemical and structural properties of lidocaine-based ionic liquids with anti-inflammatory anions , 2020, RSC advances.

[52]  S. Mitragotri,et al.  Oral delivery of sorafenib through spontaneous formation of ionic liquid nanocomplexes. , 2020, Journal of controlled release : official journal of the Controlled Release Society.

[53]  W. Zhuang,et al.  Stable Dispersed Zeolitic Imidazolate Framework/Graphene Oxide Nanocomposites in Ionic Liquids Resulting in High Lubricating Performance , 2020, Advanced Materials Interfaces.

[54]  Ana Rita Dias,et al.  Synthesis and Antibacterial Activity of Ionic Liquids and Organic Salts Based on Penicillin G and Amoxicillin hydrolysate Derivatives against Resistant Bacteria , 2020, Pharmaceutics.

[55]  A. Nowak,et al.  Enhancement of ibuprofen solubility and skin permeation by conjugation with l-valine alkyl esters , 2020, RSC advances.

[56]  Hongming Zhang,et al.  Improving dermal delivery of hyaluronic acid by ionic liquids for attenuating skin dehydration. , 2020, International journal of biological macromolecules.

[57]  M. Moniruzzaman,et al.  Development, formulation and optimization of a novel biocompatible ionic liquids dispersant for the effective oil spill remediation. , 2020, Chemosphere.

[58]  R. Atkin,et al.  Amphiphilic nanostructure in choline carboxylate and amino acid ionic liquids and solutions. , 2020, Physical chemistry chemical physics : PCCP.

[59]  J. Palomar,et al.  Cation and anion effect on the biodegradability and toxicity of imidazolium- and choline-based ionic liquids. , 2020, Chemosphere.

[60]  M. Moniruzzaman,et al.  An Overview on the Toxicological Properties of Ionic Liquids toward Microorganisms , 2019, Biotechnology journal.

[61]  E. Voutsas,et al.  Synthesis of novel non-toxic naphthenic and benzoic acid ionic liquids. Structure-properties relationship and evaluation of their biodegradability potential , 2019 .

[62]  A. Detsi,et al.  Synthesis of novel multi-OH functionalized ionic liquid and its application as dual catalyst-solvent for the one-pot synthesis 4H-pyrans , 2019, Journal of Molecular Liquids.

[63]  M. Moniruzzaman,et al.  Synthesis, characterization, ecotoxicity and biodegradability evaluations of novel biocompatible surface active lauroyl sarcosinate ionic liquids. , 2019, Chemosphere.

[64]  R. Reis,et al.  Biocompatible ionic liquids: fundamental behaviours and applications. , 2019, Chemical Society reviews.

[65]  E. Baydoun,et al.  Aurone derivatives as promising antibacterial agents against resistant Gram-positive pathogens. , 2019, European journal of medicinal chemistry.

[66]  S. Mitragotri,et al.  Reply to Rogers and Gurau: Definitions of ionic liquids and deep eutectic solvents , 2018, Proceedings of the National Academy of Sciences.

[67]  R. Rogers,et al.  Is “choline and geranate” an ionic liquid or deep eutectic solvent system? , 2018, Proceedings of the National Academy of Sciences.

[68]  A. Detsi,et al.  2-Hydroxyethyl-1-ammonium 3-hydroxypropane-1-sulfonate: a biodegradable and recyclable ionic liquid for the one-pot synthesis of 2-amino-3-cyano-4H-pyrans , 2018, Journal of the Iranian Chemical Society.

[69]  S. Mitragotri,et al.  Transdermal insulin delivery using choline‐based ionic liquids (CAGE) , 2018, Journal of controlled release : official journal of the Controlled Release Society.

[70]  S. Mitragotri,et al.  Mechanism of Antibacterial Activity of Choline-Based Ionic Liquids (CAGE). , 2018, ACS biomaterials science & engineering.

[71]  E. Voutsas,et al.  Green biotransformations catalysed by enzyme-inorganic hybrid nanoflowers in environmentally friendly ionic solvents , 2018, Environmental science and pollution research international.

[72]  A. Detsi,et al.  Synthesis and characterization of silver nanoparticles using biodegradable protic ionic liquids , 2017 .

[73]  Sarah Kirchhecker,et al.  Amino acid based ionic liquids: A green and sustainable perspective , 2016 .

[74]  M. El-Harbawi,et al.  Understanding the physical properties, toxicities and anti-microbial activities of choline-amino acid-based salts: Low-toxic variants of ionic liquids , 2016 .

[75]  A. Detsi,et al.  Hydroxyl ammonium ionic liquids as media for biocatalytic oxidations , 2016 .

[76]  E. Voutsas,et al.  Synthesis of Biscoumarins Using Recyclable and Biodegradable Task-Specific Ionic Liquids , 2013 .

[77]  Robin D. Rogers,et al.  Understanding the Effects of Ionicity in Salts, Solvates, Co-Crystals, Ionic Co-Crystals, and Ionic Liquids, Rather than Nomenclature, Is Critical to Understanding Their Behavior , 2013 .