Scatter estimation scaling with all count use by employing discrete Data Consistency Conditions

A typical PET acquisition does not separate true coincidence events from scatter because of poor energy resolution. The Single Scatter Simulation (SSS) is used to estimate scatter distribution sequentially with emission activity image reconstruction. Due to unknown activity outside the field of view and approximation in the SSS itself, scatter distribution is scaled to measure data in a sinogram region where true activity projection is known to be zero. Such a region typically contains a small number of counts and tail of scatter distribution and this can result in errors in the scaling parameter estimation. In this work we present a method to scale known scatter distribution to measured data in regions where contributions from truly coincidence emission images can be expected. In other words, all counts are used in the scatter scaling problem. We explore a constraint where true coincidence sinogram distribution must be a projection of some activity image, the Data Consistency Conditions. An iterative algorithm is presented that reconstructs the emission image from available counts. Scatter scaling estimation is a by-product of this reconstruction. Initial results show that scaling parameters can be estimated in regions where both scatter and true coincidence events coexist.

[1]  M. Defrise,et al.  Time-of-flight PET data determine the attenuation sinogram up to a constant , 2012, Physics in medicine and biology.

[2]  A. R. De Pierro,et al.  On the relation between the ISRA and the EM algorithm for positron emission tomography , 1993, IEEE Trans. Medical Imaging.

[3]  C. C. Watson,et al.  New, faster, image-based scatter correction for 3D PET , 1999, 1999 IEEE Nuclear Science Symposium. Conference Record. 1999 Nuclear Science Symposium and Medical Imaging Conference (Cat. No.99CH37019).

[4]  H. Malcolm Hudson,et al.  Accelerated image reconstruction using ordered subsets of projection data , 1994, IEEE Trans. Medical Imaging.

[5]  Hakan Erdogan,et al.  Monotonic algorithms for transmission tomography , 2002, 5th IEEE EMBS International Summer School on Biomedical Imaging, 2002..

[6]  Patrick Dupont,et al.  Reducing loss of image quality because of the attenuation artifact in uncorrected PET whole-body images. , 2002, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[7]  C.C. Watson,et al.  Advances in scatter correction for 3D PET/CT , 2004, IEEE Symposium Conference Record Nuclear Science 2004..

[8]  F. Jansen,et al.  A new algorithm for scaling of PET scatter estimates using all coincidence events , 2007, 2007 IEEE Nuclear Science Symposium Conference Record.