Graphical knowledge acquisition for medical diagnostic expert systems

Like many textbook authors use text systems for writing their books, expert system authors should have easy to use knowledge acquisition systems for entering and testing their knowledge bases by themselves without much help from 'knowledge engineers'. In this paper, we report on a graphical knowledge acquisition tool (CLASSIKA) based on an expert system shell for heuristic classification (MED2) and designed for direct use by domain experts. We demonstrate how the system has been used for building a rather large expert system for diagnosing rheumatology diseases which is now being tested in clinical use.

[1]  Brian R. Gaines,et al.  Comparing conceptual structures: consensus, conflict, correspondence and contrast , 1989 .

[2]  H. J. Moens,et al.  Comparison of rheumatological diagnoses by a Bayesian program and by physicians. , 1991 .

[3]  Mark A. Musen,et al.  Conceptual models of interactive knowledge acquisition tools , 1989 .

[4]  Christopher K. Riesbeck,et al.  Experience, Memory and Reasoning , 1986 .

[5]  Bob J. Wielinga,et al.  KADS: a modelling approach to knowledge engineering , 1992 .

[6]  Gary S. Kahn,et al.  TEST: A Model-driven Application Shell , 1987, AAAI.

[7]  Jeffrey M. Bradshaw,et al.  Expertise Transfer and Complex Problems: Using AQUINAS as a Knowledge-Acquisition Workbench for Knowledge-Based Systems , 1987, Int. J. Man Mach. Stud..

[8]  F. Puppe,et al.  A Knowledge Representation Concept Facilitating Construction and Maintenance of Large Knowledge Bases , 1988, Methods of Information in Medicine.

[9]  Koton Phyllis,et al.  Using experience in learning and problem solving , 1988 .

[10]  Stefan Schewe,et al.  Patient's and Physician's Opinion about Computer Expert Systems , 1991, AIME.

[11]  Frank Puppe,et al.  Requirements for a classification expert system shell and their realization in Med 2 , 1987, Appl. Artif. Intell..

[12]  William J. Clancey,et al.  The Epistemology of a Rule-Based Expert System - A Framework for Explanation , 1981, Artif. Intell..

[13]  L. Kingsland,et al.  The AI/RHEUM knowledge-based computer consultant system in rheumatology. Performance in the diagnosis of 59 connective tissue disease patients from Japan. , 1988, Arthritis and rheumatism.

[14]  Mark A. Musen.  Automated generation of model-based knowledge acquisition tools , 1989 .

[15]  William J. Long,et al.  Flexible reasoning about patient management using multiple models , 1991, Artif. Intell. Medicine.

[16]  Edward H. Shortliffe,et al.  From certainty factors to belief networks , 1992, Artif. Intell. Medicine.

[17]  Larry J. Eshelman,et al.  MOLE: A Tenacious Knowledge-Acquisition Tool , 1987, Int. J. Man Mach. Stud..

[18]  William J. Clancey,et al.  Heuristic Classification , 1986, Artif. Intell..

[19]  Randall Davis,et al.  Interactive Transfer of Expertise: Acquisition of New Inference Rules , 1993, IJCAI.

[20]  Frank Puppe,et al.  Belief Revision in Diagnosis , 1987, GWAI.

[21]  John H. Boose,et al.  A Knowledge Acquisition Program for Expert Systems Based on Personal Construct Psychology , 1985, Int. J. Man Mach. Stud..

[22]  Perry L. Miller.  Medical Plan-Analysis: The Attending System , 1983, IJCAI.

[23]  Karsten Poeck,et al.  Common Ground and Differences of the KADS and Strong-Problem-Solving-Shell Approach , 1992, EKAW.

[24]  Frank Puppe,et al.  Systematic introduction to expert systems - knowledge representations and problem-solving methods , 2011 .

[25]  Judea Pearl,et al.  Probabilistic reasoning in intelligent systems - networks of plausible inference , 1991, Morgan Kaufmann series in representation and reasoning.

[26]  H. E. Pople,et al.  Internist-I, an Experimental Computer-Based Diagnostic Consultant for General Internal Medicine , 1982 .

[27]  E H Shortliffe,et al.  PUFF: an expert system for interpretation of pulmonary function data. , 1982, Computers and biomedical research, an international journal.

[28]  Lawrence M. Fagan,et al.  Use of a Domain Model to Drive an Interactive Knowledge-Editing Tool , 1987, Int. J. Man Mach. Stud..

[29]  Larry Eshelman,et al.  MOLE: A Knowledge-Acquisition Tool for Cover-and-Differentiate Systems , 1988 .

[30]  Sandra Marcus,et al.  Automating Knowledge Acquisition for Expert Systems , 1988 .

[31]  田中 穂積.  E.H.Shortliffe 著, "Computer-Based Medical Consultations : MYCIN", American Elsevier, A4判, 264ぺージ, \10,080, 1976 , 1978 .

[32]  Edward H. Shortliffe,et al.  The treatment advice of a computer-based cancer chemotherapy protocol advisor. , 1985, Annals of internal medicine.

[33]  Gary Kahn.  MORE: From Observing Knowledge Engineers to Automating Knowledge Acquisition , 1988 .

[34]  Randolph A. Miller,et al.  Towards computer-assisted maintenance of medical knowledge bases , 1990, Artif. Intell. Medicine.

[35]  Frank Puppe,et al.  Improving Case Based Classification with Expert Knowledge , 1991, GWAI.