Cardiolipin content is involved in liver mitochondrial energy wasting associated with cancer-induced cachexia without the involvement of adenine nucleotide translocase.

[1]  V. Baracos,et al.  Understanding the mechanisms and treatment options in cancer cachexia , 2013, Nature Reviews Clinical Oncology.

[2]  B. Liu,et al.  L-carnitine ameliorates cancer cachexia in mice by regulating the expression and activity of carnitine palmityl transferase , 2011, Cancer biology & therapy.

[3]  C. Couet,et al.  Efficiency of oxidative phosphorylation in liver mitochondria is decreased in a rat model of peritoneal carcinosis. , 2011, Journal of hepatology.

[4]  C. Couet,et al.  N-3 PUFA-Enriched Diet Delays the Occurrence of Cancer Cachexia in Rat With Peritoneal Carcinosis , 2010, Nutrition and cancer.

[5]  S. Claypool Cardiolipin, a critical determinant of mitochondrial carrier protein assembly and function. , 2009, Biochimica et biophysica acta.

[6]  M. Klingenberg Cardiolipin and mitochondrial carriers. , 2009, Biochimica et biophysica acta.

[7]  L. Mccargar,et al.  A viscerally driven cachexia syndrome in patients with advanced colorectal cancer: contributions of organ and tumor mass to whole-body energy demands. , 2009, The American journal of clinical nutrition.

[8]  P. Portincasa,et al.  Mitochondrial dysfunction in rat with nonalcoholic fatty liver Involvement of complex I, reactive oxygen species and cardiolipin. , 2007, Biochimica et biophysica acta.

[9]  P. Ritz,et al.  Adenine nucleotide translocator promotes oxidative phosphorylation and mild uncoupling in mitochondria after dexamethasone treatment. , 2007, American journal of physiology. Endocrinology and metabolism.

[10]  G. Paradies,et al.  Interaction of peroxidized cardiolipin with rat‐heart mitochondrial membranes: Induction of permeability transition and cytochrome c release , 2006, FEBS letters.

[11]  B. Cannon,et al.  Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2 may be responsible for basal and fatty-acid-induced uncoupling respectively. , 2006, The Biochemical journal.

[12]  J. Morley,et al.  Cachexia: pathophysiology and clinical relevance. , 2006, The American journal of clinical nutrition.

[13]  D. Wallace,et al.  The basal proton conductance of mitochondria depends on adenine nucleotide translocase content. , 2005, The Biochemical journal.

[14]  P. Shanthi,et al.  Energy-modulating vitamins – a new combinatorial therapy prevents cancer cachexia in rat mammary carcinoma , 2005, British Journal of Nutrition.

[15]  P. Ritz,et al.  Dexamethasone treatment specifically increases the basal proton conductance of rat liver mitochondria , 2003, FEBS letters.

[16]  G. Migliorati,et al.  Exogenous Phospholipids Specifically Affect Transmembrane Potential of Brain Mitochondria and Cytochrome cRelease* , 2002, The Journal of Biological Chemistry.

[17]  G. Nitenberg,et al.  Nutritional support of the cancer patient: issues and dilemmas. , 2000, Critical reviews in oncology/hematology.

[18]  G. Brown,et al.  Cellular energy utilization and molecular origin of standard metabolic rate in mammals. , 1997, Physiological reviews.

[19]  U. Muscatello,et al.  Effect of cardiolipin on functional properties of isolated rat liver mitochondria , 1997, Biochemistry and molecular biology international.

[20]  M. Rigoulet,et al.  Effect of polyunsaturated fatty acids deficiency on oxidative phosphorylation in rat liver mitochondria. , 1996, Biochimica et biophysica acta.

[21]  M. Burt,et al.  Depletion of high energy phosphate compouds in the tumor-bearing state and reversal after tumor resection. , 1996, Surgery.

[22]  M. Burt,et al.  Energy depletion in the liver and in isolated hepatocytes of tumor-bearing animals. , 1995, The Journal of surgical research.

[23]  M. Hayer‐Hartl,et al.  Molecular species of cardiolipin in relation to other mitochondrial phospholipids. Is there an acyl specificity of the interaction between cardiolipin and the ADP/ATP carrier? , 1991, European journal of biochemistry.

[24]  V. Skulachev,et al.  Inhibitors of the ATP/ADP antiporter suppress stimulation of mitochondrial respiration and H+ permeability by palmitate and anionic detergents , 1990, FEBS letters.

[25]  J. Duszyński,et al.  Relationship between the energy cost of ATP transport and ATP synthesis in mitochondria. , 1981, Biochimica et biophysica acta.

[26]  Joseph R. Bertino,et al.  Prognostic effect of weight loss prior to chemotherapy in cancer patients. Eastern Cooperative Oncology Group. , 1980, The American journal of medicine.

[27]  W. J. Dyer,et al.  A rapid method of total lipid extraction and purification. , 1959, Canadian journal of biochemistry and physiology.

[28]  G. Sparagna,et al.  Role of cardiolipin alterations in mitochondrial dysfunction and disease. , 2007, American journal of physiology. Cell physiology.

[29]  Shaoyu Zhou,et al.  Cumulative and irreversible cardiac mitochondrial dysfunction induced by doxorubicin. , 2001, Cancer research.