Electrospun palladium (IV)-doped copper oxide composite nanofibers for non-enzymatic glucose sensors

Pd (IV)-doped CuO oxide composite nanofibers (PCNFs) have been successfully fabricated via electrospinning and then employed to construct an amperometric non-enzymatic glucose sensor. The PCNFs based glucose sensors display distinctly enhanced electrocatalytic activity towards the oxidation of glucose, showing significantly lower overvoltage (0.32 V) and ultrafast (1 s) and ultrasensitive current (1061.4 μA mM−1 cm−2) response with a lower detection limit of 1.9 × 10−8 M (S/N = 3). Additionally, excellent selectivity, reproducibility and stability have also been obtained. These results indicate that PCNFs are promising candidates for amperometric non-enzymatic glucose detection.

[1]  Wei Zheng,et al.  Highly sensitive and stable humidity nanosensors based on LiCl doped TiO2 electrospun nanofibers. , 2008, Journal of the American Chemical Society.

[2]  Younan Xia,et al.  Electrospinning of Nanofibers: Reinventing the Wheel? , 2004 .

[3]  Peixiang Cai,et al.  A sensitive nonenzymatic glucose sensor in alkaline media with a copper nanocluster/multiwall carbon nanotube-modified glassy carbon electrode. , 2007, Analytical biochemistry.

[4]  Aicheng Chen,et al.  Amperometric glucose sensor based on platinum–iridium nanomaterials , 2008 .

[5]  B. Zeng,et al.  Mesoporous MnO2 as enzyme immobilization host for amperometric glucose biosensor construction , 2008 .

[6]  Wei Wang,et al.  Zinc oxide nanofiber gas sensors via electrospinning , 2008 .

[7]  Fen Xu,et al.  Glucose biosensor based on electrodeposition of platinum nanoparticles onto carbon nanotubes and immobilizing enzyme with chitosan-SiO(2) sol-gel. , 2008, Biosensors & bioelectronics.

[8]  Haoqing Hou,et al.  Electrospun Palladium Nanoparticle‐Loaded Carbon Nanofibers and Their Electrocatalytic Activities towards Hydrogen Peroxide and NADH , 2008 .

[9]  A. Turner,et al.  Home blood glucose biosensors: a commercial perspective. , 2005, Biosensors & bioelectronics.

[10]  A. Turner,et al.  Glucose oxidase: an ideal enzyme , 1992 .

[11]  In-Hyeong Yeo,et al.  Anodic response of glucose at copper-based alloy electrodes , 2000 .

[12]  A. Aboukaïs,et al.  Studies of the activation process over Pd perovskite-type oxides used for catalytic oxidation of toluene , 2007 .

[13]  Wei‐De Zhang,et al.  Nonenzymatic electrochemical glucose sensor based on MnO2/MWNTs nanocomposite , 2008 .

[14]  Wenbo Song,et al.  Preparation and Electrocatalytic Performance of Functionalized Copper-Based Nanoparticles Supported on the Gold Surface , 2006 .

[15]  Xin Li,et al.  Self-assembled microstructure of carbon nanotubes for enzymeless glucose sensor , 2009 .

[16]  Aicheng Chen,et al.  Nonenzymatic electrochemical glucose sensor based on nanoporous PtPb networks. , 2008, Analytical chemistry.

[17]  Sun-il Mho,et al.  Electrocatalytic response of carbohydrates at copper-alloy electrodes , 2001 .

[18]  Richard G. Compton,et al.  The use of copper(II) oxide nanorod bundles for the non-enzymatic voltammetric sensing of carbohydrates and hydrogen peroxide , 2008 .

[19]  Yu Lei,et al.  CuO Nanospheres Based Nonenzymatic Glucose Sensor , 2008 .

[20]  Bin Chen,et al.  A novel method for making CuO superfine fibres via an electrospinning technique , 2003 .