Constrained SPICE in Volterra-Laguerre modeling of human smooth pursuit

The Volterra model is a well-established option in nonlinear black-box system identification. However, the estimated model is often over-parametrized. This paper presents an approach to reducing the number of parameters of a Volterra model with the kernels parametrized in the orthonormal basis of Laguerre functions by estimating it with a sparse estimation algorithm subject to constraints. The resulting parameter estimates are scrutinized for parameter redundancy and functional dependence by principal component analysis. The benefits of this approach are illustrated by identifying the human smooth pursuit system. Previous studies have suggested that the Volterra model structure is suitable for modeling the human smooth pursuit system both in health and disease. The data sets are obtained by eye tracking in a study performed on 7 test subjects diagnosed with Parkinson's disease and 22 healthy control subjects. In terms of output error, the reduced model has similar performance to that of the full model.

[1]  Jan Swevers,et al.  Identification of nonlinear systems using Polynomial Nonlinear State Space models , 2010, Autom..

[2]  Lennart Ljung,et al.  Nonlinear black-box modeling in system identification: a unified overview , 1995, Autom..

[3]  Thomas B. Schön,et al.  System identification of nonlinear state-space models , 2011, Autom..

[4]  Alexander Medvedev,et al.  Mathematical modeling and grey-box identification of the human smooth pursuit mechanism , 2010, 2010 IEEE International Conference on Control Applications.

[5]  S. Billings Nonlinear System Identification: NARMAX Methods in the Time, Frequency, and Spatio-Temporal Domains , 2013 .

[6]  I. M. Wilkinson,et al.  The influence of drugs and alcohol upon human eye movement. , 1976, Proceedings of the Royal Society of Medicine.

[7]  E. Bai,et al.  Block Oriented Nonlinear System Identification , 2010 .

[8]  C Kennard,et al.  Ocular motor and manual tracking in Parkinson's disease and the effect of treatment. , 1987, Journal of neurology, neurosurgery, and psychiatry.

[9]  Peng Shi,et al.  Adaptive sparse Volterra system identification with ℓ0-norm penalty , 2011, Signal Process..

[10]  R. Tibshirani Regression Shrinkage and Selection via the Lasso , 1996 .

[11]  Alexander Medvedev,et al.  Visual stimulus design in parameter estimation of the human smooth pursuit system from eye-tracking data , 2013, 2013 American Control Conference.

[12]  Alexander Medvedev,et al.  Dynamic smooth pursuit gain estimation from eye tracking data , 2011, IEEE Conference on Decision and Control and European Control Conference.

[13]  Miriam Rodrigues Silvestre,et al.  Statistical Evaluation of Pruning Methods Applied in Hidden Neurons of the MLP Neural Network , 2006, IEEE Latin America Transactions.

[14]  G. O'driscoll,et al.  Smooth pursuit in schizophrenia: A meta-analytic review of research since 1993 , 2008, Brain and Cognition.

[15]  Georgios B. Giannakis,et al.  Sparsity-aware estimation of nonlinear Volterra kernels , 2009, 2009 3rd IEEE International Workshop on Computational Advances in Multi-Sensor Adaptive Processing (CAMSAP).

[16]  S. Marino,et al.  Quantitative Analysis of Pursuit Ocular Movements in Parkinson’s Disease by Using a Video-Based Eye Tracking System , 2007, European Neurology.

[17]  Petre Stoica,et al.  SPICE and LIKES: Two hyperparameter-free methods for sparse-parameter estimation , 2012, Signal Process..

[18]  Alexander Medvedev,et al.  Non-parametric analysis of eye-tracking data by anomaly detection , 2013, 2013 European Control Conference (ECC).

[19]  M. Schetzen The Volterra and Wiener Theories of Nonlinear Systems , 1980 .

[20]  J. Westin,et al.  Levodopa/carbidopa microtablets in Parkinson’s disease: a study of pharmacokinetics and blinded motor assessment , 2017, European Journal of Clinical Pharmacology.

[21]  Alexander Medvedev,et al.  Volterra modeling of the Smooth Pursuit System with application to motor symptoms characterization in Parkinson's disease , 2014, 2014 European Control Conference (ECC).

[22]  Georgios B. Giannakis,et al.  Sparse Volterra and Polynomial Regression Models: Recoverability and Estimation , 2011, IEEE Transactions on Signal Processing.

[23]  V. Marmarelis Identification of nonlinear biological systems using laguerre expansions of kernels , 1993, Annals of Biomedical Engineering.

[24]  Peter Thier,et al.  The neural basis of smooth pursuit eye movements in the rhesus monkey brain , 2008, Brain and Cognition.