SpheroidSim—Preliminary evaluation of a new computational tool to predict the influence of cell cycle time and phase fraction on spheroid growth

There is a relative paucity of research that integrates materials science and bioengineering with computational simulations to decipher the intricate processes promoting cancer progression. Therefore, a first‐generation computational model, SpheroidSim, was developed that includes a biological data set derived from a bioengineered spheroid model to obtain a quantitative description of cell kinetics.

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