Photo‐Assisted Multi‐Component Reactions (MCR): A New Entry to 2‐Pyrimidinethiones

[1]  Peter Wipf,et al.  Contributions of academic laboratories to the discovery and development of chemical biology tools. , 2013, Journal of medicinal chemistry.

[2]  P. Abdelnur,et al.  Ionic Liquid Effect over the Biginelli Reaction under Homogeneous and Heterogeneous Catalysis , 2013 .

[3]  J. Clark,et al.  The combined role of catalysis and solvent effects on the Biginelli reaction: improving efficiency and sustainability. , 2013, Chemistry.

[4]  Alexandre F. Gomes,et al.  The Biginelli reaction with an imidazolium-tagged recyclable iron catalyst: kinetics, mechanism, and antitumoral activity. , 2013, Chemistry.

[5]  Yanguang Wang,et al.  Highly enantioselective Biginelli reaction catalyzed by SPINOL-phosphoric acids. , 2012, Organic & biomolecular chemistry.

[6]  A. Minassi,et al.  Pietro Biginelli: The Man Behind the Reaction , 2011 .

[7]  J. N. Moorthy,et al.  Enantioselective organocatalytic Biginelli reaction: dependence of the catalyst on sterics, hydrogen bonding, and reinforced chirality. , 2011, The Journal of organic chemistry.

[8]  O. Rath,et al.  Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol. , 2010, Journal of medicinal chemistry.

[9]  J. Pandey,et al.  L-Proline catalyzed multicomponent reaction of 3,4-dihydro-(2H)-pyran, urea/thiourea, and aldehydes: diastereoselective synthesis of hexahydropyrano pyrimidinones (thiones) , 2009 .

[10]  L. Gong,et al.  Highly enantioselective organocatalytic Biginelli and Biginelli-like condensations: reversal of the stereochemistry by tuning the 3,3'-disubstituents of phosphoric acids. , 2009, Journal of the American Chemical Society.

[11]  Jie‐Ping Wan,et al.  Chemo-/regioselective synthesis of 6-unsubstituted dihydropyrimidinones, 1,3-thiazines and chromones via novel variants of Biginelli reaction. , 2009, Chemical communications.

[12]  Shaowu Wang,et al.  Synthesis of Substituted 5‐(Pyrrolidin‐2‐yl)tetrazoles and Their Application in the Asymmetric Biginelli Reaction , 2009 .

[13]  P. Wipf,et al.  A Precursor-specific Role for Hsp40/Hsc70 during Tail-anchored Protein Integration at the Endoplasmic Reticulum* , 2008, Journal of Biological Chemistry.

[14]  Xiaoming Feng,et al.  An enantioselective biginelli reaction catalyzed by a simple chiral secondary amine and achiral brønsted acid by a dual-activation route. , 2008, Chemistry.

[15]  L. Gong,et al.  Asymmetric organocatalytic Biginelli reactions: a new approach to quickly access optically active 3,4-dihydropyrimidin-2-(1H)-ones. , 2007, Chemistry.

[16]  Pierre Thuéry,et al.  Structure of Human Eg5 in Complex with a New Monastrol-based Inhibitor Bound in the R Configuration* , 2007, Journal of Biological Chemistry.

[17]  J. Kremsner,et al.  5-aroyl-3,4-dihydropyrimidin-2-one library generation via automated sequential and parallel microwave-assisted synthesis techniques. , 2007, Journal of combinatorial chemistry.

[18]  L. Gong,et al.  Highly enantioselective organocatalytic Biginelli reaction. , 2006, Journal of the American Chemical Society.

[19]  A. Wu,et al.  Two novel diastereoselective three-component reactions of alkenes or 3,4-dihydro-(2H)-pyran with urea/thiourea-aldehyde mixtures: [4 + 2] cycloaddition vs Biginelli-type reaction. , 2006, Organic letters.

[20]  Yijun Huang,et al.  Highly enantioselective Biginelli reaction using a new chiral ytterbium catalyst: asymmetric synthesis of dihydropyrimidines. , 2006, Journal of the American Chemical Society.

[21]  A. Wu,et al.  A novel three-component one-pot reaction involving alkynes, urea or thiourea, and aldehydes. , 2005, Organic letters.

[22]  I. Vernos,et al.  Development and Biological Evaluation of Potent and Specific Inhibitors of Mitotic Kinesin Eg5 , 2005, Chembiochem : a European journal of chemical biology.

[23]  Shenlin Huang,et al.  Highly Chemoselective Multicomponent Biginelli‐Type Condensations of Cycloalkanones, Urea or Thiourea and Aldehydes , 2005 .

[24]  P. Gans,et al.  Interaction of the mitotic inhibitor monastrol with human kinesin Eg5. , 2003, Biochemistry.

[25]  Timothy J Mitchison,et al.  Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5. , 2002, Chemistry & biology.

[26]  C. Kappe.  Recent advances in the Biginelli dihydropyrimidine synthesis. New tricks from an old dog. , 2000, Accounts of chemical research.

[27]  J. Barrow,et al.  In Vitro and in Vivo Evaluation of Dihydropyrimidinone C-5 Amides as Potent and Selective α1A Receptor Antagonists for the Treatment of Benign Prostatic Hyperplasia , 2000 .

[28]  A Hedberg,et al.  Dihydropyrimidine calcium channel blockers. 3. 3-Carbamoyl-4-aryl-1,2,3,4-tetrahydro-6-methyl-5-pyrimidinecarboxylic acid esters as orally effective antihypertensive agents. , 1991, Journal of medicinal chemistry.

[29]  E. Hurst.  EXPERIMENTAL CHEMOTHERAPY OF INFECTION WITH AGENTS OF THE PSITTACOSIS‐LYMPHOGRANULOMA‐TRACHOMA GROUP , 1962, Annals of the New York Academy of Sciences.