Glucosamine induces lipid accumulation and adipogenic change in C2C12 myoblasts.

[1]  F. Schick,et al.  Intramyocellular lipids and insulin resistance , 2004, Diabetes, obesity & metabolism.

[2]  G. Cartee,et al.  Prolonged incubation in PUGNAc results in increased protein O-Linked glycosylation and insulin resistance in rat skeletal muscle. , 2004, Diabetes.

[3]  R. Vigneri,et al.  Rats that are made insulin resistant by glucosamine treatment have impaired skeletal muscle insulin receptor phosphorylation. , 2003, Metabolism: clinical and experimental.

[4]  K. Kristiansen,et al.  Roles of peroxisome proliferator-activated receptors delta and gamma in myoblast transdifferentiation. , 2003, Experimental cell research.

[5]  G. Cooney,et al.  The role of intramuscular lipid in insulin resistance. , 2003, Acta physiologica Scandinavica.

[6]  G. Hart,et al.  O‐GlcNAc turns twenty: functional implications for post‐translational modification of nuclear and cytosolic proteins with a sugar , 2003, FEBS letters.

[7]  M. Matsuda,et al.  Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors. , 2003, Diabetes.

[8]  C. Dani,et al.  Inhibition of myogenesis enables adipogenic trans‐differentiation in the C2C12 myogenic cell line , 2001, FEBS letters.

[9]  I. G. Fantus,et al.  Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[10]  G. Hart,et al.  O-Glycosylation of Nuclear and Cytosolic Proteins , 2000, The Journal of Biological Chemistry.

[11]  G. Cooney,et al.  Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle. , 2000, American journal of physiology. Endocrinology and metabolism.

[12]  Xiaoyong Yang,et al.  Phosphorylation of Human Glutamine:Fructose-6-phosphate Amidotransferase by cAMP-dependent Protein Kinase at Serine 205 Blocks the Enzyme Activity* , 2000, The Journal of Biological Chemistry.

[13]  I. G. Fantus,et al.  Glucosamine activates the plasminogen activator inhibitor 1 gene promoter through Sp1 DNA binding sites in glomerular mesangial cells. , 2000, Diabetes.

[14]  C. Kahn,et al.  Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle. , 1999, Diabetes.

[15]  C. Burant,et al.  Effects of troglitazone on substrate storage and utilization in insulin-resistant rats. , 1999, The American journal of physiology.

[16]  Guoxun Chen,et al.  Tissue triglycerides, insulin resistance, and insulin production: implications for hyperinsulinemia of obesity. , 1997, The American journal of physiology.

[17]  J. Proietto,et al.  Increased flux through the hexosamine biosynthesis pathway inhibits glucose transport acutely by activation of protein kinase C. , 1997, The Biochemical journal.

[18]  M. Buse,et al.  Increased activity of the hexosamine synthesis pathway in muscles of insulin-resistant ob/ob mice. , 1997, The American journal of physiology.

[19]  S. Lillioja,et al.  Skeletal Muscle Triglyceride Levels Are Inversely Related to Insulin Action , 1997, Diabetes.

[20]  D. McClain,et al.  Hexosamines and Insulin Resistance , 1996, Diabetes.

[21]  B. Fielding,et al.  Intramuscular triglyceride and muscle insulin sensitivity: evidence for a relationship in nondiabetic subjects. , 1996, Metabolism: clinical and experimental.

[22]  R. DeFronzo,et al.  Increased Glutamine:Fructose-6-Phosphate Amidotransferase Activity in Skeletal Muscle of Patients With NIDDM , 1996, Diabetes.

[23]  M. Buse,et al.  Effects of Diabetes and Hyperglycemia on the Hexosamine Synthesis Pathway in Rat Muscle and Liver , 1995, Diabetes.

[24]  L. Teboul,et al.  Thiazolidinediones and Fatty Acids Convert Myogenic Cells into Adipose-like Cells (*) , 1995, The Journal of Biological Chemistry.

[25]  B. Spiegelman,et al.  Transdifferentiation of myoblasts by the adipogenic transcription factors PPAR gamma and C/EBP alpha. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[26]  B. Spiegelman,et al.  Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor , 1994, Cell.

[27]  B. Spiegelman,et al.  mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. , 1994, Genes & development.

[28]  M. Buse,et al.  Pre-Exposure to Glucosamine Induces Insulin Resistance of Glucose Transport and Glycogen Synthesis in Isolated Rat Skeletal Muscles: Study of Mechanisms in Muscle and in Rat-1 Fibroblasts Overexpressing the Human Insulin Receptor , 1993, Diabetes.

[29]  G. Reaven Role of Insulin Resistance in Human Disease , 1988, Diabetes.

[30]  S. Stearns Carnitine content of skeletal and cardiac muscle from genetically diabetic (db/db) and control mice. , 1983, Biochemical medicine.

[31]  D. McClain Hexosamines as mediators of nutrient sensing and regulation in diabetes. , 2002, Journal of diabetes and its complications.

[32]  R. Considine,et al.  Hexosamines regulate leptin production in 3T3-L1 adipocytes through transcriptional mechanisms. , 2002, Endocrinology.

[33]  J. McGarry,et al.  Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats. , 2001, Diabetes.