Tobacco and Alcohol Use and Clinical Staging of Head and Neck Tumors

Objective:  To determine the relationship between tobacco and alcohol consumption and staging of head and neck cancer in patients treated at a referral hospital for cancer treatment.  Material and Methods: This is a cross-sectional study based on medical records of patients with head and neck cancer treated between 2008 and 2015. The following variables were considered: gender, age, marital status, educational level, place of residence, profession, affected site, clinical staging of neoplasms, histopathological diagnosis, tobacco and alcohol consumption .  Results: Of the 154 medical records analyzed, there was predominance of male patients (72.7%), single (50%), with low education (88.1%), rural workers (38.3%), residents in the state countryside (70.2%) and aged 20-94 years. T3 and T4 size tumors prevailed. Significant correlation was found between alcohol use and tumor size (p=0.03) and presence of nodules (p<0.001), as well as between alcohol use and smoking with tumor size (p=0.04) and presence of nodules (p=0.019). No correlations were observed between tobacco use and injury staging. Conclusion:  There was strong significance between tumor size and presence of nodules, both with the use of alcohol alone and with tobacco, thus suggesting the existence of important carcinogenic action of this substance.

[1]  S. Ferreira,et al.  Smoking-Alcohol-Sex Exposure and Knowledge About Oral and Oropharyngeal Cancer Among Brazilian Adolescents: An Exploratory-Observational Approach , 2020 .

[2]  Y. Wimardhani,et al.  Oral Cancer Knowledge among a Sample of Elderly People in Depok City, West Java, Indonesia , 2018 .

[3]  W. Ahrens,et al.  The influence of smoking, age and stage at diagnosis on the survival after larynx, hypopharynx and oral cavity cancers in Europe: The ARCAGE study , 2018, International journal of cancer.

[4]  Marceli de Oliveira Santos Estimativa 2018: Incidência de Câncer no Brasil , 2018 .

[5]  Swati K. Patil,et al.  Influence of risk factors on patients suffering from potentially malignant disorders and oral cancer: A case–control study , 2017, Journal of oral and maxillofacial pathology : JOMFP.

[6]  M. Oliveira,et al.  Clinical and epidemiological study in patients with oral cancer in a period of thirteen years , 2016 .

[7]  Carlos Teles Santos,et al.  Associated factors with oral cancer: a study of case control in a population of the Brazil's Northeast. , 2015, Revista brasileira de epidemiologia = Brazilian journal of epidemiology.

[8]  F. Acurcio,et al.  Sobrevida de cinco anos e fatores associados ao câncer de boca para pacientes em tratamento oncológico ambulatorial pelo Sistema Único de Saúde, Brasil , 2014 .

[9]  F. Acurcio,et al.  [Specific 5-year oral cancer survival and associated factors in cancer outpatients in the Brazilian Unified National Health System]. , 2014, Cadernos de saude publica.

[10]  M. Sant,et al.  Álcool e Câncer Bucal: Considerações sobre os Mecanismos Relacionados Alcohol and Oral Cancer: Comments on Related Mechanisms , 2008 .

[11]  C. Scully,et al.  Recent advances in Oral Oncology 2007: epidemiology, aetiopathogenesis, diagnosis and prognostication. , 2008, Oral oncology.

[12]  Y. Juliano,et al.  Estudo de variáveis demográficas, ocupacionais e co-carcinogenéticas no carcinoma espinocelular da base de língua nas mulheres , 2003 .

[13]  Craig S. Miller,et al.  Disparities in risk of and survival from oropharyngeal squamous cell carcinoma. , 2003, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[14]  V. Wünsch-Filho,et al.  The epidemiology of oral and pharynx cancer in Brazil. , 2002, Oral oncology.

[15]  C. Torres-Pereira,et al.  [Strategies for management of oral cancer in primary and secondary healthcare services]. , 2012, Cadernos de saude publica.