Delivery and fate of oral mesalamine microgranules within the human small intestine.
暂无分享,去创建一个
U. Klotz | J. Keller | P. Layer | A. Dignass | H. Goebell | P. Layer | H. Goebell
[1] S. Hanauer. Medical therapy of ulcerative colitis , 1993, The Lancet.
[2] J. Teare,et al. The mode of action of the aminosalicylates in inflammatory bowel disease , 1993 .
[3] U. Klotz,et al. Oroileal transit of slow release 5-aminosalicylic acid. , 1993, Gut.
[4] S. Hanauer,et al. Mesalamine capsules for the treatment of active Crohn's disease: results of a 16-week trial. Pentasa Crohn's Disease Study Group. , 1993, Gastroenterology.
[5] G. May,et al. Sulfasalazine Revisited , 1993, Annals of Internal Medicine.
[6] R. Modigliani,et al. Oral mesalamine (Pentasa) as maintenance treatment in Crohn's disease: a multicenter placebo-controlled study. The Groupe d'Etudes Thérapeutiques des Affections Inflammatoires Digestives (GETAID) , 1993, Gastroenterology.
[7] V. Trimble,et al. Randomised comparison of olsalazine and mesalazine in prevention of relapses in ulcerative colitis , 1992, The Lancet.
[8] A. Fitton,et al. Olsalazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in inflammatory bowel disease. , 1991, Drugs.
[9] J. Rask-Madsen,et al. Disposition of 5-aminosalicylic acid by olsalazine and three mesalazine preparations in patients with ulcerative colitis: comparison of intraluminal colonic concentrations, serum values, and urinary excretion. , 1990, Gut.
[10] B. Norlander,et al. Pharmacokinetics of a 5‐aminosalicylic acid enteric‐coated tablet in patients with Crohn's disease or ulcerative colitis and in healthy volunteers , 1990, Alimentary pharmacology & therapeutics.
[11] S. Hansen,et al. Topical and systemic availability of 5‐amino‐salicylate: comparisons of three controlled release preparations in man , 1990, Alimentary pharmacology & therapeutics.
[12] D. Giesing,et al. Effect of food coadministration on 5‐aminosalicylic acid oral suspension bioavailability , 1990, Clinical pharmacology and therapeutics.
[13] P. Layer,et al. Feedback regulation of human pancreatic secretion. Effects of protease inhibition on duodenal delivery and small intestinal transit of pancreatic enzymes. , 1990, Gastroenterology.
[14] P. Layer,et al. Human pancreatic secretion and intestinal motility: effects of ileal nutrient perfusion. , 1990, The American journal of physiology.
[15] R. V. van Hogezand,et al. Disposition of 5-aminosalicylic acid from 5-aminosalicylic acid-delivering drugs during accelerated intestinal transit in healthy volunteers. , 1989, Scandinavian journal of gastroenterology.
[16] R. N. Brogden,et al. Mesalazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in chronic inflammatory bowel disease. , 1989, Drugs.
[17] B. Norlander,et al. Pharmacokinetics of a 5‐aminosalicylic acid enteric‐coated tablet and suppository dosage form , 1989, Alimentary pharmacology & therapeutics.
[18] U. Klotz,et al. Colonic N-acetylation of 5-aminosalicylic acid in inflammatory bowel disease. , 1989, Gastroenterology.
[19] H. Spiro. Inflammatory bowel diseases—Basic research and clinical implications , 1989 .
[20] Ami,et al. Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis: a randomised trial. , 1989, BMJ.
[21] S. Riley,et al. Delayed-release mesalazine (5-aminosalicylic acid): coat dissolution and excretion in ileostomy subjects. , 1988, British journal of clinical pharmacology.
[22] J. Hardcastle,et al. Measurement of gastrointestinal pH profiles in normal ambulant human subjects. , 1988, Gut.
[23] J. Elashoff,et al. Human postprandial gastric emptying of 1-3-millimeter spheres. , 1988, Gastroenterology.
[24] S. Riley,et al. Comparison of delayed-release 5-aminosalicylic acid (mesalazine) and sulfasalazine as maintenance treatment for patients with ulcerative colitis. , 1988, Gastroenterology.
[25] P. Wesseling,et al. Double‐blind comparison of 5‐aminosalicylic acid and acetyl‐5‐aminosalicylic acid suppositories in patients with idiopathic proctitis , 1988, Alimentary pharmacology & therapeutics.
[26] E. Dimagno,et al. Human pancreatic secretion during phase II antral motility of the interdigestive cycle. , 1988, The American journal of physiology.
[27] C. Deighton,et al. Effect of polymer coating on faecal recovery of ingested 5-amino salicylic acid in patients with ulcerative colitis. , 1987, Gut.
[28] J. Hardy,et al. Evaluation of an enteric‐coated delayed‐release 5‐aminosalicylic acid tablet in patients with inflammatory bowel disease , 1987, Alimentary pharmacology & therapeutics.
[29] J. Hardy,et al. Gastrointestinal transit of an enteric‐coated delayed‐release 5‐aminosalicylic acid tablet , 1987, Alimentary pharmacology & therapeutics.
[30] L. Sutherland,et al. 5-Aminosalicylic acid enema in the treatment of distal ulcerative colitis, proctosigmoiditis, and proctitis. , 1987, Gastroenterology.
[31] A. Richens,et al. Metabolism and urinary excretion of 5-amino salicylic acid in healthy volunteers when given intravenously or released for absorption at different sites in the gastrointestinal tract. , 1987, Gut.
[32] A. Zinsmeister,et al. Effects of decreasing intraluminal amylase activity on starch digestion and postprandial gastrointestinal function in humans. , 1986, Gastroenterology.
[33] U. Klotz,et al. Clinical Pharmacokinetics of Sulphasalazine, Its Metabolites and Other Prodrugs of 5-Aminosalicylic Acid , 1985, Clinical pharmacokinetics.
[34] S. Bondesen,et al. Kinetics of 5-aminosalicylic acid after jejunal instillation in man. , 1983, British journal of clinical pharmacology.
[35] U. Klotz,et al. Specific measurement of 5-aminosalicylic acid and its acetylated metabolite in human bile. , 1983, British journal of clinical pharmacology.
[36] S. Hansen,et al. 5-aminosalicylic acid in a slow-release preparation: bioavailability, plasma level, and excretion in humans. , 1982, Gastroenterology.
[37] U. Klotz,et al. Simplified high-performance liquid chromatographic method for 5-aminosalicylic acid in plasma and urine. , 1981, Journal of chromatography.
[38] S. Truelove,et al. AN EXPERIMENT TO DETERMINE THE ACTIVE THERAPEUTIC MOIETY OF SULPHASALAZINE , 1977, The Lancet.
[39] D. Wingate,et al. A comparison of stable and 14C-labelled polyethylene glycol as volume indicators in the human jejunum 1 , 1972, Gut.
[40] Raphael Ss,et al. Deaf-mutism and type-II hyperlipoproteinaemia. , 1970 .
[41] A. Hofmann,et al. Simultaneous measurements of total pancreatic, biliary, and gastric outputs in man using a perfusion technique. , 1970, Gastroenterology.
[42] D. Jewell,et al. Acetylation of 5-aminosalicylic acid by isolated human colonic epithelial cells. , 1990, Clinical science.
[43] M. Rijk,et al. Disposition of 5-aminosalicylic acid by 5-aminosalicylic acid-delivering compounds. , 1988, Scandinavian journal of gastroenterology.
[44] U. Klotz,et al. A new slow-release form of 5-aminosalicylic acid for the oral treatment of inflammatory bowel disease. Biopharmaceutic and clinical pharmacokinetic characteristics. , 1985, Arzneimittel-Forschung.