Effect of Purmorphamine on Osteogenic Differentiation of Human Mesenchymal Stem Cells in a Three-Dimensional Dynamic Culture System

[1]  M. Baghaban Eslaminejad,et al.  The effect of nano-scale topography on osteogenic differentiation of mesenchymal stem cells. , 2013, Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia.

[2]  K. Anselme,et al.  Role of culture conditions on in vitro transformation and cellular colonization of biomimetic HA-Col scaffolds , 2013, Biomatter.

[3]  A. Papadimitropoulos,et al.  A collagen network phase improves cell seeding of open‐pore structure scaffolds under perfusion , 2013, Journal of tissue engineering and regenerative medicine.

[4]  R. Nerem,et al.  Differentiation Patterns of Embryonic Stem Cells in Two- versus Three-Dimensional Culture , 2013, Cells Tissues Organs.

[5]  M. Najar,et al.  The effect of purmorphamine and sirolimus on osteogenic differentiation of human bone marrow-derived mesenchymal stem cells. , 2013, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[6]  A. Lindahl,et al.  Virtual Ligand-Based Screening Reveals Purmorphamine Analogs with the Capacity to Induce the Osteogenic Differentiation of Human Mesenchymal Stem Cells , 2012, Cells Tissues Organs.

[7]  Y. Kim,et al.  Characterization of different subpopulations from bone marrow-derived mesenchymal stromal cells by alkaline phosphatase expression. , 2012, Stem cells and development.

[8]  M. Beloti,et al.  Hedgehog signaling and osteoblast gene expression are regulated by purmorphamine in human mesenchymal stem cells , 2012, Journal of cellular biochemistry.

[9]  J. Reichelt,et al.  Two- and Three-Dimensional Culture of Keratinocyte Stem and Precursor Cells Derived from Primary Murine Epidermal Cultures , 2012, Stem Cell Reviews and Reports.

[10]  Ali Khademhosseini,et al.  SAM-based cell transfer to photopatterned hydrogels for microengineering vascular-like structures. , 2011, Biomaterials.

[11]  G. Lin,et al.  Tissue distribution of mesenchymal stem cell marker Stro-1. , 2011, Stem cells and development.

[12]  C. Dani,et al.  Activation of Hedgehog Signaling Inhibits Osteoblast Differentiation of Human Mesenchymal Stem Cells , 2009, Stem cells.

[13]  G. Hunter,et al.  Bone sialoprotein-collagen interaction promotes hydroxyapatite nucleation. , 2008, Matrix biology : journal of the International Society for Matrix Biology.

[14]  M. Karsdal,et al.  Bone turnover and bone collagen maturation in osteoporosis: effects of antiresorptive therapies , 2008, Osteoporosis International.

[15]  N. Riobo,et al.  Pathways of signal transduction employed by vertebrate Hedgehogs. , 2007, The Biochemical journal.

[16]  J. Klein-Nulend,et al.  Osteogenesis versus chondrogenesis by BMP-2 and BMP-7 in adipose stem cells. , 2006, Biochemical and biophysical research communications.

[17]  Maria Kasper,et al.  GLI transcription factors: mediators of oncogenic Hedgehog signalling. , 2006, European journal of cancer.

[18]  L. Griffith,et al.  Capturing complex 3D tissue physiology in vitro , 2006, Nature Reviews Molecular Cell Biology.

[19]  D. Prockop,et al.  Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. , 2006, Cytotherapy.

[20]  R. Sandberg,et al.  Gene expression perturbation in vitro--a growing case for three-dimensional (3D) culture systems. , 2005, Seminars in cancer biology.

[21]  M. Beloti,et al.  Purmorphamine enhances osteogenic activity of human osteoblasts derived from bone marrow mesenchymal cells , 2005, Cell biology international.

[22]  P. Schultz,et al.  Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway. , 2004, Chemistry & biology.

[23]  C. Maniatopoulos,et al.  Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats , 1988, Cell and Tissue Research.

[24]  D. Wendt,et al.  Oscillating perfusion of cell suspensions through three‐dimensional scaffolds enhances cell seeding efficiency and uniformity , 2003, Biotechnology and bioengineering.

[25]  A. Abbott.  Cell culture: Biology's new dimension , 2003, Nature.

[26]  J. Davies,et al.  Use of a biomimetic strategy to engineer bone. , 2003, Journal of biomedical materials research. Part A.

[27]  G. Reilly,et al.  BMP Responsiveness in Human Mesenchymal Stem Cells , 2003, Connective tissue research.

[28]  Robert A. Weinberg,et al.  Taking the Study of Cancer Cell Survival to a New Dimension , 2002, Cell.

[29]  Peter G Schultz,et al.  A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells. , 2002, Journal of the American Chemical Society.

[30]  Antonios G. Mikos,et al.  Fluid flow increases mineralized matrix deposition in 3D perfusion culture of marrow stromal osteoblasts in a dose-dependent manner , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[31]  J. Aubin,et al.  Individual osteoblasts in the developing calvaria express different gene repertoires. , 2001, Bone.

[32]  J. Screen,et al.  Further Characterization of Cells Expressing STRO‐1 in Cultures of Adult Human Bone Marrow Stromal Cells , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[33]  M. Pittenger,et al.  Multilineage potential of adult human mesenchymal stem cells. , 1999, Science.

[34]  S. Gronthos,et al.  Differential Cell Surface Expression of the STRO‐1 and Alkaline Phosphatase Antigens on Discrete Developmental Stages in Primary Cultures of Human Bone Cells , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[35]  J. Aubin,et al.  Advances in the osteoblast lineage. , 1998, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[36]  J. Aubin,et al.  Cell sorting enriches osteogenic populations in rat bone marrow stromal cell cultures. , 1997, Bone.

[37]  H. Ohuchi,et al.  Fibroblasts expressing Sonic hedgehog induce osteoblast differentiation and ectopic bone formation , 1997, FEBS letters.

[38]  S. Bruder,et al.  Osteogenic differentiation of purified, culture‐expanded human mesenchymal stem cells in vitro , 1997, Journal of cellular biochemistry.

[39]  A. Scutt,et al.  Bone marrow cells are targets for the anabolic actions of prostaglandin E2 on bone: Induction of a transition from nonadherent to adherent osteoblast precursors , 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[40]  K. Takaoka,et al.  Alterations in the expression of osteonectin, osteopontin and osteocalcin mRNAs during the development of skeletal tissues in vivo. , 1994, Bone and mineral.

[41]  P. Simmons,et al.  Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1. , 1991, Blood.

[42]  W. Butler,et al.  Developmental expression of 44-kDa bone phosphoprotein (osteopontin) and bone gamma-carboxyglutamic acid (Gla)-containing protein (osteocalcin) in calcifying tissues of rat. , 1988, Differentiation; research in biological diversity.

[43]  K. Lee.  Hard tissue growth, repair and remineralization , 1973 .