Prediction of Protein-Protein Interaction Sites Using Support Vector Machines

Protein-protein interactions play an important role in various biological processes. Over the past few years, several studies have been made on protein interface and those results enable us to obtain massive data on various aspects of protein interface. The problem that we have to consider next is predicting the interaction sites on the protein surface. Although several prediction methods are developed, there is still room for improvement. The purpose of this study is to develop a reliable prediction system of protein-protein interaction sites from their three-dimensional structure.