Screening of traditional medicinal plant extracts and compounds identifies a potent anti-leishmanial diarylheptanoid from Siphonochilus aethiopicus
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J. Igoli | R. Pandey | Ravi Jain | E. Madan | Jhalak Singhal | I. Ezenyi | A. Chakrabarti | N. Igoli | Shailja Singh | Gajala Deethamvali Ghousepeer | Amrita Chakrabarti
[1] P. Srivastava,et al. Host SUMOylation Pathway Negatively Regulates Protective Immune Responses and Promotes Leishmania donovani Survival , 2022, Frontiers in Cellular and Infection Microbiology.
[2] Jeremy D. DeBarry,et al. VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center , 2021, Nucleic Acids Res..
[3] N. Al-Tannak,et al. Antiplasmodial activity of a novel diarylheptanoid from Siphonochilus aethiopicus , 2020, Natural product research.
[4] Samuel Ehiabhi Okhale,et al. Ethnopharmacology-aided antiplasmodial evaluation of six selected plants used for malaria treatment in Nigeria. , 2020, Journal of ethnopharmacology.
[5] Vijeta Sharma,et al. Natural Product Inspired Novel Indole based Chiral Scaffold Kills Human Malaria Parasites via Ionic Imbalance Mediated Cell Death , 2019, Scientific Reports.
[6] U. Anand,et al. A Comprehensive Review on Medicinal Plants as Antimicrobial Therapeutics: Potential Avenues of Biocompatible Drug Discovery , 2019, Metabolites.
[7] R. Aebersold,et al. The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis , 2019, Cell.
[8] R. Madhubala,et al. The arginine sensing and transport binding sites are distinct in the human pathogen Leishmania , 2019, PLoS neglected tropical diseases.
[9] S. Pati,et al. Plasmodium palmitoylation machinery engineered in E. coli for high‐throughput screening of palmitoyl acyl‐transferase inhibitors , 2019, FEBS open bio.
[10] Muhammed Tilahun Muhammed,et al. Homology modeling in drug discovery: Overview, current applications, and future perspectives , 2018, Chemical biology & drug design.
[11] M. Locatelli,et al. A Review on the Dietary Flavonoid Tiliroside. , 2018, Comprehensive reviews in food science and food safety.
[12] D. Boakye,et al. In vitro antiprotozoan activity and mechanisms of action of selected Ghanaian medicinal plants against Trypanosoma, Leishmania, and Plasmodium parasites , 2018, Phytotherapy research : PTR.
[13] O. Ogbole,et al. Antimicrobial and antiprotozoal activities of twenty-four Nigerian medicinal plant extracts , 2018, South African Journal of Botany.
[14] Torsten Schwede,et al. SWISS-MODEL: homology modelling of protein structures and complexes , 2018, Nucleic Acids Res..
[15] W. Sippl,et al. Compounds from African Medicinal Plants with Activities Against Selected Parasitic Diseases: Schistosomiasis, Trypanosomiasis and Leishmaniasis , 2018, Natural Products and Bioprospecting.
[16] G. A. Gutiérrez-Rebolledo,et al. Natural compounds and extracts from Mexican medicinal plants with anti-leishmaniasis activity: An update. , 2017, Asian Pacific journal of tropical medicine.
[17] A. Nadhman,et al. Plants as Antileishmanial Agents: Current Scenario , 2016, Phytotherapy research : PTR.
[18] Z. Shinwari,et al. Ethnomedicines and anti-parasitic activities of Pakistani medicinal plants against Plasmodia and Leishmania parasites , 2016, Annals of Clinical Microbiology and Antimicrobials.
[19] O. Singh,et al. Current challenges in treatment options for visceral leishmaniasis in India: a public health perspective , 2016, Infectious Diseases of Poverty.
[20] A. Amaral,et al. Natural Products: Insights into Leishmaniasis Inflammatory Response , 2015, Mediators of inflammation.
[21] M. Idu,et al. Ethnomedicinal survey of plants used in the treatment of malaria in Southern Nigeria. , 2015, Journal of ethnopharmacology.
[22] P. Veras,et al. Advances in Development of New Treatment for Leishmaniasis , 2015, BioMed research international.
[23] N. Ghorai,et al. Protective effect of Croton caudatus Geisel leaf extract against experimental visceral leishmaniasis induces proinflammatory cytokines in vitro and in vivo. , 2015, Experimental parasitology.
[24] K. Otun,et al. Chemical Composition, Antioxidant and Antimicrobial Potentials of Icacina trichantha Oliv. Leaf Extracts , 2015 .
[25] M. Wilson,et al. Eosinophils and mast cells in leishmaniasis , 2014, Immunologic research.
[26] David J Newman,et al. Natural products: a continuing source of novel drug leads. , 2013, Biochimica et biophysica acta.
[27] B. Schmidt,et al. Structure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity , 2012, Nature Structural &Molecular Biology.
[28] N. Reiner,et al. Myeloid Cell IL-10 Production in Response to Leishmania Involves Inactivation of Glycogen Synthase Kinase-3β Downstream of Phosphatidylinositol-3 Kinase , 2012, The Journal of Immunology.
[29] Evan Bolton,et al. PubChem's BioAssay Database , 2011, Nucleic Acids Res..
[30] Yang Zhang,et al. Improving the physical realism and structural accuracy of protein models by a two-step atomic-level energy minimization. , 2011, Biophysical journal.
[31] V. Hannaert,et al. In vitro antitrypanosomal and antileishmanial activity of plants used in Benin in traditional medicine and bio-guided fractionation of the most active extract. , 2011, Journal of ethnopharmacology.
[32] A. Renslo,et al. Identification of Small Molecule Lead Compounds for Visceral Leishmaniasis Using a Novel Ex Vivo Splenic Explant Model System , 2011, PLoS neglected tropical diseases.
[33] Margarida Saraiva,et al. The regulation of IL-10 production by immune cells , 2010, Nature Reviews Immunology.
[34] M. Salvador,et al. Bioactivity of Flavonoids Isolated from Lychnophora markgravii against Leishmania amazonensis Amastigotes , 2009, Zeitschrift fur Naturforschung. C, Journal of biosciences.
[35] A. Giménez,et al. An Alkaloid Extract of Evanta, Traditionally Used as Anti‐leishmania Agent in Bolivia, Inhibits Cellular Proliferation and Interferon‐γ Production in Polyclonally Activated Cells , 2009, Scandinavian journal of immunology.
[36] Xiaohua Ma,et al. Mechanisms of drug combinations: interaction and network perspectives , 2009, Nature Reviews Drug Discovery.
[37] K. Ajibesin,et al. Ethnobotanical survey of Akwa Ibom State of Nigeria. , 2008, Journal of ethnopharmacology.
[38] E. von Stebut,et al. Distinct roles for IL-1 receptor type I signaling in early versus established Leishmania major infections. , 2006, The Journal of investigative dermatology.
[39] A. Celada,et al. Arginase and polyamine synthesis are key factors in the regulation of experimental leishmaniasis in vivo , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[40] Y. Belkaid,et al. Interleukin 1α Promotes Th1 Differentiation and Inhibits Disease Progression in Leishmania major–susceptible BALB/c Mice , 2003, The Journal of experimental medicine.
[41] Wan-Wan Lin,et al. Inhibition of cytokine‐induced JAK‐STAT signalling pathways by an endonuclease inhibitor aurintricarboxylic acid , 2002, British journal of pharmacology.
[42] D. Sacks,et al. The immunology of susceptibility and resistance to Leishmania major in mice , 2002, Nature Reviews Immunology.
[43] Wan-Wan Lin,et al. Aurintricarboxylic acid protects against cell death caused by lipopolysaccharide in macrophages by decreasing inducible nitric-oxide synthase induction via IkappaB kinase, extracellular signal-regulated kinase, and p38 mitogen-activated protein kinase inhibition. , 2002, Molecular pharmacology.
[44] B. Liu,et al. Role of Nitric Oxide in Inflammation‐Mediated Neurodegeneration , 2002, Annals of the New York Academy of Sciences.
[45] H. Rui,et al. Activation of the Jak2-Stat5 Signaling Pathway in Nb2 Lymphoma Cells by an Anti-apoptotic Agent, Aurintricarboxylic Acid* , 1998, The Journal of Biological Chemistry.
[46] R. G. Kemp,et al. Aurintricarboxylic acid is a potent inhibitor of phosphofructokinase. , 1989, The Biochemical journal.
[47] L. Gradoni,et al. The Leishmaniases: Old Neglected Tropical Diseases , 2018, Springer International Publishing.
[48] L. Liaudet,et al. Nitric oxide and peroxynitrite in health and disease. , 2007, Physiological reviews.
[49] S. Gordon. Alternative activation of macrophages , 2003, Nature Reviews Immunology.