Estimation of respiration rate from ECG, BP and PPG signals using empirical mode decomposition

Estimation of respiration rates from electrocardiogram (ECG), blood pressure (BP) and photoplethysmographic (PPG) signals would be an alternative approach for obtaining respiration related information. This process is useful in situations when, ECG, BP and PPG but not respiration is routinely monitored or in cases where, the cardiac arrhythmias are to be studied in correlation with respiratory information and is extremely important. There have been several efforts on ECG-Derived Respiration (EDR), BP-Derived Respiration (BDR) and PPG Derived Respiration (PDR). These methods are based on different signal processing techniques like filtering, wavelets and other statistical methods, which work by extraction of respiratory trend embedded into various physiological signals, as an additive component, or an amplitude modulated (AM) component or frequency modulated (FM) component. The proposed method is a robust, yet simple and makes use of derived Intrinsic Mode Functions (IMF) using Empirical Mode Decomposition (EMD). Test results on ECG, BP and PPG signals of the well known MIMIC database from Physiobank archive reveal that the proposed EMD method has efficiently extracted respiratory information from ECG, BP and PPG signals. The evaluated similarity parameters in both time and frequency domains for original and estimated respiratory rates have shown the superiority of the method.

[1]  W. Einthoven,et al.  On the direction and manifest size of the variations of potential in the human heart and on the influence of the position of the heart on the form of the electrocardiogram. , 1950, American heart journal.

[2]  B. Frey,et al.  Pulse oximetry for assessment of pulsus paradoxus: a clinical study in children , 2009, Intensive Care Medicine.

[3]  Thomas W. Calvert,et al.  A model to estimate respiration from vectorcardiogram measurements , 1974, Annals of Biomedical Engineering.

[4]  T. Findley,et al.  Derivation of respiration from electrocardiogram during heart rate variability studies , 1994, Computers in Cardiology 1994.

[5]  Yue-Der Lin,et al.  Coherence Analysis between Respiration and PPG Signal by Bivariate AR Model , 2009 .

[6]  L. Nilsson,et al.  Monitoring of respiratory rate in postoperative care using a new photoplethysmographic technique , 2004, Journal of Clinical Monitoring and Computing.

[7]  R. Pallàs-Areny,et al.  The effect of respiration-induced heart movements on the ECG , 1989, IEEE Transactions on Biomedical Engineering.

[8]  A. Johansson,et al.  Estimation of respiratory volumes from the photoplethysmographic signal. Part I: experimental results , 2006, Medical & Biological Engineering & Computing.

[9]  Daming Wei,et al.  Derivation of Respiratory Signal from Single- Channel ECGs Based on Source Statistics , 2004 .

[10]  N. Huang,et al.  The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis , 1998, Proceedings of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences.

[11]  M S Spach,et al.  Influence of respiration on recording cardiac potentials. Isopotential surface-mapping and vectorcardiographic studies. , 1967, The American journal of cardiology.

[12]  James McNames,et al.  Estimation of respiration from physiologic pressure signals , 2003, Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439).

[13]  P. Rautaharju,et al.  Body Position, Electrode Level, and Respiration Effects on the Frank Lead Electrocardiogram , 1976, Circulation.

[14]  T. Tamura,et al.  Photoplethysmographic measurement of heart and respiratory rates using digital filters , 1993, Proceedings of the 15th Annual International Conference of the IEEE Engineering in Medicine and Biology Societ.

[15]  George B. Moody,et al.  Derivation of Respiratory Signals from Multi-lead ECGs , 2008 .

[16]  Professor P. Å. Öberg,et al.  Estimation of respiratory volumes from the photoplethysmographic signal. Part 2: a model study , 2006, Medical & Biological Engineering & Computing.