Nonlinear Adaptive Signal Processing Improves the Diagnostic Quality of Transabdominal Fetal Electrocardiography

The abdominal fetal electrocardiogram (fECG) conveys valuable information that can aid clinicians with the diagnosis and monitoring of a potentially at risk fetus during pregnancy and in childbirth. This chapter primarily focuses on noninvasive (external and indirect) transabdominal fECG monitoring. Even though it is the preferred monitoring method, unlike its classical invasive (internal and direct) counterpart (transvaginal monitoring), it may be contaminated by a variety of undesirable signals that deteriorate its quality and reduce its value in reliable detection of hypoxic conditions in the fetus. A stronger maternal electrocardiogram (the mECG signal) along with technical and biological artifacts constitutes the main interfering signal components that diminish the diagnostic quality of the transabdominal fECG recordings. Currently, transabdominal fECG monitoring relies solely on the determination of the fetus’ pulse or heart rate (FHR) by detecting RR intervals and does not take into account the morphology and duration of the fECG waves (P, QRS, T), intervals, and segments, which collectively convey very useful diagnostic information in adult cardiology. The main reason for the exclusion of these valuable pieces of information in the determination of the fetus’ status from clinical practice is the fact that there are no sufficiently reliable and well-proven techniques for accurate extraction of fECG signals and robust derivation of these informative features. To address this shortcoming in fetal cardiology, we focus on adaptive signal processing methods and pay particular attention to nonlinear approaches that carry great promise in improving the quality of transabdominal fECG monitoring and consequently impacting fetal cardiolo‐ gy in clinical practice. Our investigation and experimental results by using clinicalquality synthetic data generated by our novel fECG signal generator suggest that adaptive neuro-fuzzy inference systems could produce a significant advancement in fetal monitoring during pregnancy and childbirth. The possibility of using a single device to © 2016 The Author(s). Licensee InTech. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. leverage two advanced methods of fetal monitoring, namely noninvasive cardiotocog‐ raphy (CTG) and ST segment analysis (STAN) simultaneously, to detect fetal hypoxic conditions is very promising.

[1]  Khaled Assaleh,et al.  Extraction of Fetal Electrocardiogram Using Adaptive Neuro-Fuzzy Inference Systems , 2007, IEEE Transactions on Biomedical Engineering.

[2]  Zayed M. Ramadan,et al.  Adaptive filtering primer with MATLAB , 2006 .

[3]  Changshui Zhang,et al.  Semi-blind source extraction for fetal electrocardiogram extraction by combining non-Gaussianity and time-correlation , 2007, Neurocomputing.

[4]  Andrew G. Favret,et al.  Computer matched filter location of fetalR-waves , 1968, Medical and biological engineering.

[5]  Lotfi A. Zadeh,et al.  Soft computing and fuzzy logic , 1994, IEEE Software.

[6]  T. Kailath,et al.  Fast, recursive-least-squares transversal filters for adaptive filtering , 1984 .

[7]  K. Nicolaides,et al.  Prenatal asphyxia, hyperlacticaemia, hypoglycaemia, and erythroblastosis in growth retarded fetuses. , 1987, British medical journal.

[8]  Radek Martinek,et al.  The Real Implementation of ANFIS Channel Equalizer on the System of Software-Defined Radio , 2014 .

[9]  K. Maršál,et al.  Cardiotocography only versus cardiotocography plus ST analysis of fetal electrocardiogram for intrapartum fetal monitoring: a Swedish randomised controlled trial , 2001, The Lancet.

[10]  R. E. Tainsh,et al.  Fetal heart rate monitoring. , 1983, American journal of obstetrics and gynecology.

[11]  A. Bousbia-Salah,et al.  Combination of a FIR filter with a Genetic algorithm for the extraction of a fetal ECG , 2010, 2010 Conference Record of the Forty Fourth Asilomar Conference on Signals, Systems and Computers.

[12]  Arnon Cohen,et al.  Detection of fetal ECG with IIR adaptive filtering and genetic algorithms , 1999, 1999 IEEE International Conference on Acoustics, Speech, and Signal Processing. Proceedings. ICASSP99 (Cat. No.99CH36258).

[13]  W. A. Coberly,et al.  ECG data compression techniques-a unified approach , 1990, IEEE Transactions on Biomedical Engineering.

[14]  Gustavo Camps-Valls,et al.  Foetal ECG recovery using dynamic neural networks , 2004, Artif. Intell. Medicine.

[15]  Piet Bergveld,et al.  A New Technique for the Suppression of the MECG , 1981, IEEE Transactions on Biomedical Engineering.

[16]  Zhaosheng Teng,et al.  Comparative Study of Influence of Noise on Power Frequency Estimation of Sine wave Using Interpolation FFT , 2014 .

[17]  Y. Datian,et al.  Application of wavelet analysis in detection of fetal ECG , 1996, Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[18]  B. Widrow,et al.  Adaptive noise cancelling: Principles and applications , 1975 .

[19]  Lotfi A. Zadeh,et al.  Fuzzy logic, neural networks, and soft computing , 1993, CACM.

[20]  G. Camps,et al.  Methods to evaluate the performance of fetal electrocardiogram extraction algorithms , 2001, Computers in Cardiology 2001. Vol.28 (Cat. No.01CH37287).

[21]  R. Swarnalath,et al.  A Novel Technique for Extraction of FECG using Multi Stage Adaptive Filtering , 2010 .

[22]  Radek Martinek,et al.  Use of adaptive filtering for noise reduction in communications systems , 2010, 2010 International Conference on Applied Electronics.

[23]  Deniz Erdogmus,et al.  Independent components analysis for fetal electrocardiogram extraction: a case for the data efficient Mermaid algorithm , 2003, 2003 IEEE XIII Workshop on Neural Networks for Signal Processing (IEEE Cat. No.03TH8718).

[24]  R. Martinek,et al.  A System for Improving the Diagnostic Quality of Fetal Electrocardiogram , 2012 .

[25]  Hung T. Nguyen,et al.  A First Course in Fuzzy and Neural Control , 2002 .

[26]  C. Jutten,et al.  Filtering noisy ECG signals using the extended kalman filter based on a modified dynamic ECG model , 2005, Computers in Cardiology, 2005.

[27]  Karim Faez,et al.  Fetal Electrocardiogram Signal Extraction by ANFIS Trained with PSO Method , 2012 .

[28]  José M. F. Moura,et al.  Biomedical Signal Processing , 2018, Series in BioEngineering.

[29]  E. Hon,et al.  Averaging techniques in fetal electrocardiography , 2006, Medical electronics and biological engineering.

[30]  A Al-Zaben,et al.  Extraction of foetal ECG by combination of singular value decomposition and neuro-fuzzy inference system , 2006, Physics in medicine and biology.

[31]  Reza Sameni,et al.  Extraction of Fetal Cardiac Signals from an Array of Maternal Abdominal Recordings , 2008 .

[32]  Radek Martinek,et al.  A novel LabVIEW-based multi-channel non-invasive abdominal maternal-fetal electrocardiogram signal generator , 2016, Physiological measurement.

[33]  M. Omair Ahmad,et al.  A high-throughput DLMS adaptive algorithm , 2005, 2005 IEEE International Symposium on Circuits and Systems.

[34]  Sami Ekici,et al.  An adaptive neuro-fuzzy inference system (ANFIS) model for wire-EDM , 2009, Expert Syst. Appl..

[35]  A. Immanuel Selvakumar,et al.  Issues and research on foetal electrocardiogram signal elicitation , 2014, Biomed. Signal Process. Control..

[36]  L. Burattini,et al.  Noninvasive Fetal Electrocardiography: An Overview of the Signal Electrophysiological Meaning, Recording Procedures, and Processing Techniques , 2015, Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.

[37]  Stanly Johnson Jeyaraj,et al.  Adaptive Neuro Fuzzy Inference System for Extraction of fECG , 2005, 2005 Annual IEEE India Conference - Indicon.

[38]  Christian Jutten,et al.  Fetal ECG Extraction by Extended State Kalman Filtering Based on Single-Channel Recordings , 2013, IEEE Transactions on Biomedical Engineering.

[39]  Petr Musílek,et al.  Harvesting-aware control of wireless sensor nodes using fuzzy logic and differential evolution , 2014, 2014 Eleventh Annual IEEE International Conference on Sensing, Communication, and Networking Workshops (SECON Workshops).

[40]  S. T. Alexander,et al.  Adaptive Signal Processing: Theory and Applications , 1986 .

[41]  Radek Martinek,et al.  Enhanced processing and analysis of multi-channel non-invasive abdominal foetal ECG signals during labor and delivery , 2015 .

[42]  Lotfi A. Zadeh,et al.  Fuzzy logic = computing with words , 1996, IEEE Trans. Fuzzy Syst..

[43]  E. Ifeachor,et al.  Techniques for optimal enhancement and feature extraction of fetal electrocardiogram , 1995 .

[44]  S. Suja Priyadharsini,et al.  An Efficient Soft-Computing Technique for Extracting Fetal ECG from Maternal ECG Signal , 2011 .

[45]  Radek Martinek,et al.  Refining the diagnostic quality of the abdominal fetal electrocardiogram using the techniques of artificial intelligence , 2012 .

[46]  R. Swarnalath,et al.  Maternal ECG Cancellation in Abdominal Signal Using ANFIS and Wavelets , 2010 .

[47]  Rabab Kreidieh Ward,et al.  Extraction of fetal ECG using adaptive Volterra filters , 2008, 2008 16th European Signal Processing Conference.

[48]  Yanjun Zeng,et al.  Research of fetal ECG extraction using wavelet analysis and adaptive filtering , 2013, Comput. Biol. Medicine.

[49]  Wei Zheng,et al.  Noninvasive fetal ECG estimation using adaptive comb filter , 2013, Comput. Methods Programs Biomed..

[50]  Joos Vandewalle,et al.  Fetal electrocardiogram extraction by blind source subspace separation , 2000, IEEE Transactions on Biomedical Engineering.

[51]  Radek Martinek,et al.  Virtual simulator for the generation of patho-physiological foetal ECGs during the prenatal period , 2015 .

[52]  C. Jutten,et al.  What ICA Provides for ECG Processing: Application to Noninvasive Fetal ECG Extraction , 2006, 2006 IEEE International Symposium on Signal Processing and Information Technology.

[53]  Zhaosheng Teng,et al.  Triangular Self-Convolution Window With Desirable Sidelobe Behaviors for Harmonic Analysis of Power System , 2010, IEEE Transactions on Instrumentation and Measurement.

[54]  Radek Martinek,et al.  Modelling of Fetal Hypoxic Conditions Based on Virtual Instrumentation , 2015, AECIA.

[55]  Jyh-Shing Roger Jang,et al.  ANFIS: adaptive-network-based fuzzy inference system , 1993, IEEE Trans. Syst. Man Cybern..

[56]  Radek Martinek,et al.  A Robust Approach For Acoustic Noise Suppression In Speech Using ANFIS , 2015 .

[57]  Shahriar Negahdaripour,et al.  A new method for the extraction of fetal ECG from the composite abdominal signal , 2000, IEEE Transactions on Biomedical Engineering.

[58]  Mamun Bin Ibne Reaz,et al.  Adaptive linear neural network filter for fetal ECG extraction , 2004, International Conference on Intelligent Sensing and Information Processing, 2004. Proceedings of.