Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level
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Ping Liu | Huanming Yang | Fei Wang | C. Lindskog | L. Bolund | Xiuqing Zhang | P. Carmeliet | J. Mulder | Xun Xu | Hui Jiang | F. Pontén | M. Uhlén | L. Fagerberg | E. Sjöstedt | Lihua Luo | Xue Liang | Lin Lin | Yonglun Luo | Max J. Karlsson | Joanna Kalucka | L. D. de Rooij | Jiacheng Zhu | Dongsheng Chen | Lin Xie | R. Helmig | Xiangning Ding | J. Haskó | Wendi Wu | Zhiyuan Lv | Haoyu Wang | Aiping Wu | Niels Jessen | Peiwen Ding | Yuting Yuan | C. Brandt | Saga Bolund | Lijing Zhang | Yanan Wei | Wandong Zhao | Runchu Li | Qiuyu Qin | Yi Jia | Min Pu | Fang Chen | J. Herold | N. Jessen | Linn Fagerberg
[1] Huanming Yang,et al. Genome-wide annotation of protein-coding genes in pig , 2022, BMC Biology.
[2] J. Houp,et al. First clinical‐grade porcine kidney xenotransplant using a human decedent model , 2022, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[3] Xiaochen Bo,et al. clusterProfiler 4.0: A universal enrichment tool for interpreting omics data , 2021, Innovation.
[4] V. Gladyshev,et al. A pig BodyMap transcriptome reveals diverse tissue physiologies and evolutionary dynamics of transcription , 2021, Nature Communications.
[5] P. Carmeliet,et al. Tumor vessel co-option probed by single-cell analysis. , 2021, Cell reports.
[6] Matthew S Macauley,et al. Regulation of microglia population dynamics throughout development, health, and disease , 2021, Glia.
[7] Ping Liu,et al. A high-resolution cell atlas of the domestic pig lung and an online platform for exploring lung single-cell data. , 2021, Journal of genetics and genomics = Yi chuan xue bao.
[8] Xun Xu,et al. Single-cell atlas of domestic pig cerebral cortex and hypothalamus. , 2021, Science bulletin.
[9] J. Lunney,et al. Reference Transcriptomes of Porcine Peripheral Immune Cells Created Through Bulk and Single-Cell RNA Sequencing , 2021, bioRxiv.
[10] Owen J. L. Rackham,et al. ShinyCell: simple and sharable visualization of single-cell gene expression data , 2021, Bioinform..
[11] Haixi Sun,et al. Cross-species single-cell transcriptomic analysis reveals pre-gastrulation developmental differences among pigs, monkeys, and humans , 2021, Cell Discovery.
[12] Y. Goo,et al. An experimental pig model with outer retinal degeneration induced by temporary intravitreal loading of N-methyl-N-nitrosourea during vitrectomy , 2021, Scientific reports.
[13] Hannah A. Pliner,et al. A human cell atlas of fetal gene expression , 2020, Science.
[14] C. Lindskog,et al. Enhanced Validation of Antibodies Enables the Discovery of Missing Proteins , 2020, Journal of proteome research.
[15] Owen J. L. Rackham,et al. ShinyCell: Simple and sharable visualisation of single-cell gene expression data , 2020, bioRxiv.
[16] Catherine L. Worth,et al. Cells of the adult human heart , 2020, Nature.
[17] Hiroki Asari,et al. Feedback from retinal ganglion cells to the inner retina , 2020, bioRxiv.
[18] Lihua Zhang,et al. Inference and analysis of cell-cell communication using CellChat , 2020, Nature Communications.
[19] Irving L. Weissman,et al. A single-cell transcriptomic atlas characterizes ageing tissues in the mouse , 2020, Nature.
[20] A single-cell approach to engineer CD8+ T cells targeting cytomegalovirus , 2020, Cellular & Molecular Immunology.
[21] M. Goumans,et al. TGF-β-Induced Endothelial to Mesenchymal Transition in Disease and Tissue Engineering , 2020, Frontiers in Cell and Developmental Biology.
[22] Huanming Yang,et al. Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis. , 2020, Cell metabolism.
[23] I. Amit,et al. Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program , 2020, Cell.
[24] Dan Zhang,et al. Construction of a human cell landscape at single-cell level , 2020, Nature.
[25] H. Kandori. Biophysics of rhodopsins and optogenetics , 2020, Biophysical Reviews.
[26] L. Bolund,et al. Single-Cell Transcriptome Atlas of Murine Endothelial Cells , 2020, Cell.
[27] J. I. Izpisúa Belmonte,et al. Single-Cell Transcriptomic Atlas of Primate Ovarian Aging , 2020, Cell.
[28] Tiffany M. Tang,et al. Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer’s Disease Brains , 2020, International journal of molecular sciences.
[29] Huanming Yang,et al. An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates. , 2020, Cancer cell.
[30] Mercedes Fernandez,et al. Interplay Between Macrophages and Angiogenesis: A Double-Edged Sword in Liver Disease , 2019, Front. Immunol..
[31] L. Bolund,et al. Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation. , 2019, Journal of the American Society of Nephrology : JASN.
[32] I. Amit,et al. Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program , 2019, Cell.
[33] Fenglin Liu,et al. Systematic comparative analysis of single-nucleotide variant detection methods from single-cell RNA sequencing data , 2019, Genome Biology.
[34] D. Sachs,et al. Transplanting organs from pigs to humans , 2019, Science Immunology.
[35] P. Carmeliet,et al. The metabolic engine of endothelial cells , 2019, Nature metabolism.
[36] Jonathan S. Packer,et al. A lineage-resolved molecular atlas of C. elegans embryogenesis at single-cell resolution , 2019, Science.
[37] A. Puliafito,et al. Dynamic Interplay between Pericytes and Endothelial Cells during Sprouting Angiogenesis , 2019, Cells.
[38] Masato Hoshi,et al. A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys , 2019, Nature Communications.
[39] E. Wolf,et al. Genetically modified pigs as donors of cells, tissues, and organs for xenotransplantation , 2019, Animal frontiers : the review magazine of animal agriculture.
[40] Xinran Dong,et al. Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis. , 2019, Cell stem cell.
[41] J. Bischoff. Endothelial-to-Mesenchymal Transition. , 2019, Circulation research.
[42] Geng Chen,et al. Single-Cell RNA-Seq Technologies and Related Computational Data Analysis , 2019, Front. Genet..
[43] S. Jimenez,et al. Endothelial to Mesenchymal Transition: Role in Physiology and in the Pathogenesis of Human Diseases. , 2019, Physiological reviews.
[44] Jonathan S. Packer,et al. A lineage-resolved molecular atlas of C. elegans embryogenesis at single-cell resolution , 2019, Science.
[45] Asghar Fallah,et al. Therapeutic targeting of angiogenesis molecular pathways in angiogenesis-dependent diseases. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[46] Hui Hu,et al. AnimalTFDB 3.0: a comprehensive resource for annotation and prediction of animal transcription factors , 2018, Nucleic Acids Res..
[47] Gary D Bader,et al. Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations , 2018, Nature Communications.
[48] C. Lindskog,et al. Enhanced validation of antibodies for research applications , 2018, Nature Communications.
[49] James T. Webber,et al. Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris , 2018, Nature.
[50] P. ten Dijke,et al. The therapeutic potential of targeting the endothelial-to-mesenchymal transition , 2018, Angiogenesis.
[51] P. Verstreken,et al. A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain , 2018, Cell.
[52] A. Chade,et al. A translational model of chronic kidney disease in swine. , 2018, American journal of physiology. Renal physiology.
[53] A. van Oudenaarden,et al. Single-Cell Sequencing of the Healthy and Diseased Heart Reveals Cytoskeleton-Associated Protein 4 as a New Modulator of Fibroblasts Activation , 2018, Circulation.
[54] Allon M. Klein,et al. Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo , 2018, Science.
[55] Fabian J Theis,et al. Cell type atlas and lineage tree of a whole complex animal by single-cell transcriptomics , 2018, Science.
[56] Shihua Li,et al. A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington’s Disease , 2018, Cell.
[57] B. Barres,et al. Microglia and macrophages in brain homeostasis and disease , 2017, Nature Reviews Immunology.
[58] S. Orkin,et al. Mapping the Mouse Cell Atlas by Microwell-Seq , 2018, Cell.
[59] P. ten Dijke,et al. TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases , 2017, International journal of molecular sciences.
[60] I. Amit,et al. Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner , 2017, Nature Communications.
[61] S. Tas,et al. Endothelial cells: From innocent bystanders to active participants in immune responses. , 2017, Autoimmunity reviews.
[62] Marenao Tanaka,et al. Ectopic Fatty Acid–Binding Protein 4 Expression in the Vascular Endothelium is Involved in Neointima Formation After Vascular Injury , 2017, Journal of the American Heart Association.
[63] Dylan Skola,et al. Transcriptional control of microglia phenotypes in health and disease. , 2017, The Journal of clinical investigation.
[64] E. Wolf,et al. Retinopathy with central oedema in an INSC94Y transgenic pig model of long-term diabetes , 2017, Diabetologia.
[65] Abhijeet R. Sonawane,et al. Understanding Tissue-Specific Gene Regulation , 2017, bioRxiv.
[66] E. Dejana,et al. The molecular basis of endothelial cell plasticity , 2017, Nature Communications.
[67] A. Saghatelian,et al. SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism. , 2017, Cell metabolism.
[68] W. Kiosses,et al. Macrophages form functional vascular mimicry channels in vivo , 2016, Scientific Reports.
[69] Rajesh Raju,et al. VEGF-A/VEGFR2 signaling network in endothelial cells relevant to angiogenesis , 2016, Journal of Cell Communication and Signaling.
[70] Evan Z. Macosko,et al. Comprehensive Classification of Retinal Bipolar Neurons by Single-Cell Transcriptomics , 2016, Cell.
[71] C. Tripodo,et al. C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation , 2016, Nature Communications.
[72] D. Ayares,et al. The role of genetically engineered pigs in xenotransplantation research , 2016, The Journal of pathology.
[73] M. Schwartz,et al. Endothelial-to-mesenchymal transition drives atherosclerosis progression. , 2015, The Journal of clinical investigation.
[74] M. Bacci,et al. In vitro differentiation of porcine aortic vascular precursor cells to endothelial and vascular smooth muscle cells. , 2015, American journal of physiology. Cell physiology.
[75] Jussi Taipale,et al. Conservation of transcription factor binding specificities across 600 million years of bilateria evolution , 2015, eLife.
[76] A. Regev,et al. Spatial reconstruction of single-cell gene expression , 2015, Nature Biotechnology.
[77] C. Patterson,et al. The role of BMPs in endothelial cell function and dysfunction , 2014, Trends in Endocrinology & Metabolism.
[78] N. Kostomitsopoulos,et al. A comparative anatomic and physiologic overview of the porcine heart. , 2014, Journal of the American Association for Laboratory Animal Science : JAALAS.
[79] Cole Trapnell,et al. Pseudo-temporal ordering of individual cells reveals dynamics and regulators of cell fate decisions , 2014, Nature Biotechnology.
[80] R. Virmani,et al. TGF-β Signaling Mediates Endothelial-to-Mesenchymal Transition (EndMT) During Vein Graft Remodeling , 2014, Science Translational Medicine.
[81] A. Orekhov,et al. Role of tumor associated macrophages in tumor angiogenesis and lymphangiogenesis , 2014, Front. Physiol..
[82] Hong Wang,et al. An evolving new paradigm: endothelial cells – conditional innate immune cells , 2013, Journal of Hematology & Oncology.
[83] N. Van Rooijen,et al. Macrophages play a key role in angiogenesis and adipogenesis in a mouse tissue engineering model. , 2013, Tissue engineering. Part A.
[84] R. Prather,et al. Advancing swine models for human health and diseases. , 2013, Missouri medicine.
[85] R. Prather,et al. Genetically engineered pig models for human diseases. , 2013, Annual review of animal biosciences.
[86] Lars Bolund,et al. Familial Hypercholesterolemia and Atherosclerosis in Cloned Minipigs Created by DNA Transposition of a Human PCSK9 Gain-of-Function Mutant , 2013, Science Translational Medicine.
[87] Bronwen L. Aken,et al. Analyses of pig genomes provide insight into porcine demography and evolution , 2012, Nature.
[88] M. Iruela-Arispe,et al. Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages. , 2012, Blood.
[89] J. Doudna,et al. A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , 2012, Science.
[90] T. Pannabecker. Structure and function of the thin limbs of the loop of Henle. , 2012, Comprehensive Physiology.
[91] A. Dudley,et al. Vascular Mimicry: Concepts and Implications for Anti-Angiogenic Therapy. , 2012, Current angiogenesis.
[92] G. Shi,et al. CD31: beyond a marker for endothelial cells. , 2012, Cardiovascular research.
[93] F. Clubb,et al. Swine as Models in Biomedical Research and Toxicology Testing , 2012, Veterinary pathology.
[94] Ian M. Donaldson,et al. iRefR: an R package to manipulate the iRefIndex consolidated protein interaction database , 2011, BMC Bioinformatics.
[95] Gabriel Kreiman,et al. Conservation of transcription factor binding events predicts gene expression across species , 2011, Nucleic acids research.
[96] N. Chatauret,et al. Contribution of Large Pig for Renal Ischemia-Reperfusion and Transplantation Studies: The Preclinical Model , 2011, Journal of biomedicine & biotechnology.
[97] P. Geurts,et al. Inferring Regulatory Networks from Expression Data Using Tree-Based Methods , 2010, PloS one.
[98] Sheldon Middleton,et al. Porcine ophthalmology. , 2010, The Veterinary clinics of North America. Food animal practice.
[99] Juan M. Vaquerizas,et al. A census of human transcription factors: function, expression and evolution , 2009, Nature Reviews Genetics.
[100] Surbhi Jain,et al. AIF-1 expression regulates endothelial cell activation, signal transduction, and vasculogenesis. , 2009, American journal of physiology. Cell physiology.
[101] Marie-José Goumans,et al. TGF-β signaling in vascular biology and dysfunction , 2009, Cell Research.
[102] David K. Meyerholz,et al. Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs , 2008, Science.
[103] R. Kalluri,et al. The role of endothelial-to-mesenchymal transition in cancer progression , 2008, British Journal of Cancer.
[104] M. Tansey,et al. Regulator of G-Protein Signaling 10 Promotes Dopaminergic Neuron Survival via Regulation of the Microglial Inflammatory Response , 2008, The Journal of Neuroscience.
[105] M. Rehli,et al. Expression of CD68 in Non‐Myeloid Cell Types , 2008, Scandinavian journal of immunology.
[106] Michael J. Berry,et al. Sophisticated temporal pattern recognition in retinal ganglion cells. , 2008, Journal of neurophysiology.
[107] L. Bolund,et al. Piglets born from handmade cloning, an innovative cloning method without micromanipulation. , 2007, Theriogenology.
[108] Xueli Yuan,et al. Endothelial-to-mesenchymal transition contributes to cardiac fibrosis , 2007, Nature Medicine.
[109] E. Dejana,et al. Immune Regulation by Microvascular Endothelial Cells: Directing Innate and Adaptive Immunity, Coagulation, and Inflammation1 , 2007, The Journal of Immunology.
[110] K. Red-Horse,et al. Endothelium-microenvironment interactions in the developing embryo and in the adult. , 2007, Developmental cell.
[111] D. Mukhopadhyay,et al. The porcine remnant kidney model of chronic renal insufficiency. , 2006, The Journal of surgical research.
[112] Hirohisa Yano,et al. Angiogenesis in Cancer , 2006, Vascular health and risk management.
[113] Peter Vajkoczy,et al. Combined inhibition of VEGF‐ and PDGF‐signaling enforces tumor vessel regression by interfering with pericyte‐mediated endothelial cell survival mechanisms , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[114] Benjamin D. Sachs,et al. RORα Coordinates Reciprocal Signaling in Cerebellar Development through Sonic hedgehog and Calcium-Dependent Pathways , 2003, Neuron.
[115] P. Carmeliet. Angiogenesis in health and disease , 2003, Nature Medicine.
[116] P. Newman,et al. Signal transduction pathways mediated by PECAM-1: new roles for an old molecule in platelet and vascular cell biology. , 2003, Arteriosclerosis, thrombosis, and vascular biology.
[117] John Savill,et al. Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment , 2002, Nature.
[118] R. McClellan,et al. Swine in biomedical research. , 1966, Science.