Changes in the Incidence of Gestational Trophoblastic Disease - 2000-2010 - Our Experience

Changes in the Incidence of Gestational Trophoblastic Disease - 2000-2010 - Our Experience Gestational trophoblastic disease (GTD) is a group of rare tumors that involve abnormal growth of cells inside a woman's uterus. The aim of the paper was to report the incidence of GTD in the University Hospital Center during a ten-year period. The retrospective analysis involved all medical records of women who were treated for GTD in our clinic. Histopathologic report of abortion specimen with gestational trophoblastic disease was registered and we calculated the incidence of births, abortions and total pregnancies. There were 104 patients who were treated in our clinic. The overall incidence of GTD was 1,26 per 1000 deliveries. According to our experience, a lower socio economic status may be a risk factor for GTD, apart from younger age, at least one delivery and more abortions in anamnesis. Trend kretanja incidence gestacijskih trofoblastnih bolesti u periodu 2000-2010 - naše iskustvo Gestacijske trofoblastne bolesti (GTB) predstavljaju grupu retkih tumora koji nastaju abnormalnim rastom trofoblasta. Cilj rada je da se utvrdi kolika je incidenca GTB u desetogodišnjem periodu u Univerzitetskoj klinici za ginekologiju i akušerstvo. Retrospektivnom studijom obuhvaćene su sve bolesnice koje su lečene od GTD u našoj klinici u desetogodišnjem periodu. Analizom je obuhvaćena godišnja incidenca i ukupna incidenca u odnosu na broj porođaja. Ukupno su lečene 104 bolesnice. Incidenca GTB bila je 1,26 na 1000 porođaja. Na osnovu našeg iskustva, faktori rizika za nastanak GTB su niži socioekonomski status, godine starosti i barem jedan porođaj i veći broj pobačaja u anamnezi.