A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog
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H. Lassmann | J. Selfridge | J. Zezula | P. Matthias | J. Knoblich | C. Seiser | G. Brosch | Alexandra Leopoldi | M. Schlederer | C. Schöfer | Astrid Hagelkruys | S. Lagger | O. Pusch | Yunli Xie | M. Artaker | Simon Weissmann | Julia Krahmer | Jurgen Knoblich | Matthias Artaker
[1] P. Matthias,et al. Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis , 2013, The EMBO journal.
[2] B. Cairns,et al. Histone deacetylases 1 and 2 maintain S-phase chromatin and DNA replication fork progression , 2013, Epigenetics & Chromatin.
[3] L. Tsai,et al. SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons , 2013, Nature Neuroscience.
[4] A. Bird,et al. Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor , 2013, Nature Neuroscience.
[5] L. Wessels,et al. Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function. , 2013, Blood.
[6] R. Schultz,et al. Histone Deacetylase 2 (HDAC2) Regulates Chromosome Segregation and Kinetochore Function via H4K16 Deacetylation during Oocyte Maturation in Mouse , 2013, PLoS genetics.
[7] M. Lu,et al. Development and regeneration of Sox2+ endoderm progenitors are regulated by a Hdac1/2-Bmp4/Rb1 regulatory pathway. , 2013, Developmental cell.
[8] O. Dovey,et al. Histone deacetylase (HDAC) 1 and 2 are essential for normal T cell development and genomic stability in mice , 2013, Clinical Epigenetics.
[9] M. Leitges,et al. Expression pattern of protein kinase C δ during mouse embryogenesis , 2013, BMC Developmental Biology.
[10] R. Stewart,et al. Protein Kinase C Mediated Extraembryonic Endoderm Differentiation of Human Embryonic Stem Cells , 2012, Stem cells.
[11] P. Matthias,et al. Multiple roles of class I HDACs in proliferation, differentiation, and development , 2012, Cellular and Molecular Life Sciences.
[12] Chad E. Grueter,et al. Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice , 2012, Proceedings of the National Academy of Sciences.
[13] E. Olson,et al. Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development , 2012, Proceedings of the National Academy of Sciences.
[14] G. M. Wilson,et al. Protein Kinase C (PKC) δ Suppresses Keratinocyte Proliferation by Increasing p21Cip1 Level by a KLF4 Transcription Factor-dependent Mechanism* , 2011, The Journal of Biological Chemistry.
[15] Ueli Suter,et al. HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells , 2011, Nature Neuroscience.
[16] P. Grandi,et al. Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes , 2011, Nature Biotechnology.
[17] K. Nave,et al. HDAC-mediated Deacetylation of NF-κB is Critical for Schwann cell Myelination , 2011, Nature Neuroscience.
[18] A. Kanthasamy,et al. α-Synuclein Negatively Regulates Protein Kinase Cδ Expression to Suppress Apoptosis in Dopaminergic Neurons by Reducing p300 Histone Acetyltransferase Activity , 2011, The Journal of Neuroscience.
[19] L. Kenner,et al. Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis , 2011, Cell cycle.
[20] E. Flory,et al. PKCδ‐Induced PU.1 Phosphorylation Promotes Hematopoietic Stem Cell Differentiation to Dendritic Cells , 2011, Stem cells.
[21] J. Epstein,et al. Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. , 2010, Developmental cell.
[22] C. Simone,et al. Physical and Functional HAT/HDAC Interplay Regulates Protein Acetylation Balance , 2010, Journal of biomedicine & biotechnology.
[23] A. Cataldi,et al. PKC-δ signalling pathway is involved in H9c2 cells differentiation. , 2010, Differentiation; research in biological diversity.
[24] L. Kenner,et al. Crucial function of histone deacetylase 1 for differentiation of teratomas in mice and humans , 2010, The EMBO journal.
[25] S. Jackson,et al. Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining , 2010, Nature Structural &Molecular Biology.
[26] M. Nitti,et al. PKC delta and NADPH oxidase in retinoic acid-induced neuroblastoma cell differentiation. , 2010, Cellular signalling.
[27] W. Wurst,et al. The specific role of histone deacetylase 2 in adult neurogenesis. , 2010, Neuron glia biology.
[28] Amit N. Patel,et al. PKC-delta induces cardiomyogenic gene expression in human adipose-derived stem cells. , 2010, Biochemical and biophysical research communications.
[29] H. Kohler,et al. Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression. , 2010, Genes & development.
[30] P. Kinchington,et al. Histone Deacetylases 1 and 2 Are Phosphorylated at Novel Sites during Varicella-Zoster Virus Infection , 2009, Journal of Virology.
[31] Dustin E. Schones,et al. Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes , 2009, Cell.
[32] E. Olson,et al. Histone Deacetylases 1 and 2 Form a Developmental Switch That Controls Excitatory Synapse Maturation and Function , 2009, The Journal of Neuroscience.
[33] E. Olson,et al. Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development , 2009, Proceedings of the National Academy of Sciences.
[34] E. Olson,et al. Genetic dissection of histone deacetylase requirement in tumor cells , 2009, Proceedings of the National Academy of Sciences.
[35] S. Haggarty,et al. HDAC2 negatively regulates memory formation and synaptic plasticity , 2009, Nature.
[36] C. Seiser,et al. Histone deacetylase HDAC1/HDAC2-controlled embryonic development and cell differentiation. , 2009, International Journal of Developmental Biology.
[37] Hans Clevers,et al. HDAC1 and HDAC2 Regulate Oligodendrocyte Differentiation By Disrupting β-Catenin-TCF Interaction , 2009, Nature Neuroscience.
[38] L. Thompson,et al. Therapeutic application of histone deacetylase inhibitors for central nervous system disorders , 2008, Nature Reviews Drug Discovery.
[39] Jun Qin,et al. Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells , 2008, Nature Cell Biology.
[40] W. Wurst,et al. Reduced body size and decreased intestinal tumor rates in HDAC2-mutant mice. , 2007, Cancer research.
[41] A. Kanthasamy,et al. Neuroprotective Effect of Protein Kinase Cδ Inhibitor Rottlerin in Cell Culture and Animal Models of Parkinson's Disease , 2007, Journal of Pharmacology and Experimental Therapeutics.
[42] Xiaoxia Qi,et al. Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility. , 2007, Genes & development.
[43] Jessica E. Bolden,et al. Anticancer activities of histone deacetylase inhibitors , 2006, Nature Reviews Drug Discovery.
[44] P. Majumder,et al. Protein kinase C delta inhibits Caco-2 cell proliferation by selective changes in cell cycle and cell death regulators , 2006, Oncogene.
[45] E. Seto,et al. Acetylation and deacetylation of non-histone proteins. , 2005, Gene.
[46] M. Beal,et al. Remodeling chromatin and stress resistance in the central nervous system: histone deacetylase inhibitors as novel and broadly effective neuroprotective agents. , 2005, Current drug targets. CNS and neurological disorders.
[47] A. Bird,et al. MeCP2 Behaves as an Elongated Monomer That Does Not Stably Associate with the Sin3a Chromatin Remodeling Complex* , 2004, Journal of Biological Chemistry.
[48] Jean YH Yang,et al. Bioconductor: open software development for computational biology and bioinformatics , 2004, Genome Biology.
[49] Gordon K Smyth,et al. Statistical Applications in Genetics and Molecular Biology Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments , 2011 .
[50] A. Bird,et al. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals , 2003, Nature Genetics.
[51] H. Matsuzaki,et al. Protein Kinase Cδ (PKCδ): Activation Mechanisms and Functions , 2002 .
[52] B. Schuettengruber,et al. Activation of the Mouse Histone Deacetylase 1 Gene by Cooperative Histone Phosphorylation and Acetylation , 2002, Molecular and Cellular Biology.
[53] E. Seto,et al. Regulation of Histone Deacetylase 2 by Protein Kinase CK2* , 2002, The Journal of Biological Chemistry.
[54] D. O’Carroll,et al. Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression , 2002, The EMBO journal.
[55] R. Eckert,et al. Calcium-dependent Involucrin Expression Is Inversely Regulated by Protein Kinase C (PKC)α and PKCδ* , 2002, The Journal of Biological Chemistry.
[56] K. Nakayama,et al. Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cδ , 2002, Nature.
[57] P. Brehm,et al. Regulation of Neuronal Traits by a Novel Transcriptional Complex , 2001, Neuron.
[58] F. Umansky,et al. Protein Kinase Cα and Protein Kinase Cδ Play Opposite Roles in the Proliferation and Apoptosis of Glioma Cells , 2001 .
[59] M. Posch,et al. Homo-oligomerisation and nuclear localisation of mouse histone deacetylase 1. , 2001, Journal of molecular biology.
[60] B. Schuettengruber,et al. Molecular cloning and characterization of the mouse histone deacetylase 1 gene: integration of a retrovirus in 129SV mice. , 1999, Biochimica et biophysica acta.
[61] O. Kretz,et al. Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety , 1999, Nature Genetics.
[62] Ya-Li Yao,et al. Cloning and characterization of the mouse histone deacetylase-2 gene. , 1998, The Journal of biological chemistry.
[63] C. Seiser,et al. Histone H4 acetylation during interleukin‐2 stimulation of mouse T cells , 1998, FEBS letters.
[64] S. Fukumoto,et al. Protein Kinase C δ Inhibits the Proliferation of Vascular Smooth Muscle Cells by Suppressing G1 Cyclin Expression* , 1997, The Journal of Biological Chemistry.
[65] Wen‐Ming Yang,et al. Histone Deacetylases Associated with the mSin3 Corepressor Mediate Mad Transcriptional Repression , 1997, Cell.
[66] D. Reinberg,et al. Histone Deacetylases and SAP18, a Novel Polypeptide, Are Components of a Human Sin3 Complex , 1997, Cell.
[67] C. Glass,et al. A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression , 1997, nature.
[68] L. Chin,et al. Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression , 1997, nature.
[69] K. Kent,et al. Enhancement of Migration by Protein Kinase Cα and Inhibition of Proliferation and Cell Cycle Progression by Protein Kinase Cδ in Capillary Endothelial Cells* , 1997, The Journal of Biological Chemistry.
[70] W. Kolch,et al. Overexpression of protein kinase C-delta and -epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity. , 1993, The Journal of biological chemistry.
[71] Y. Nishizuka,et al. Cell division arrest induced by phorbol ester in CHO cells overexpressing protein kinase C-delta subspecies. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[72] D. Ann,et al. PKC delta signaling: a dual role in regulating hypoxic stress-induced autophagy and apoptosis. , 2009, Autophagy.
[73] Brent A Reynolds,et al. Isolation, expansion, and differentiation of adult Mammalian neural stem and progenitor cells using the neurosphere assay. , 2009, Methods in molecular biology.
[74] Wolfgang Wurst,et al. Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity. , 2007, Nature medicine.
[75] H. Matsuzaki,et al. Protein kinase C delta (PKC delta): activation mechanisms and functions. , 2002, Journal of biochemistry.
[76] R. Eckert,et al. Calcium-dependent involucrin expression is inversely regulated by protein kinase C (PKC)alpha and PKCdelta. , 2002, The Journal of biological chemistry.
[77] F. Umansky,et al. Protein kinase Calpha and protein kinase Cdelta play opposite roles in the proliferation and apoptosis of glioma cells. , 2001, Cancer research.
[78] K. Kent,et al. Enhancement of migration by protein kinase Calpha and inhibition of proliferation and cell cycle progression by protein kinase Cdelta in capillary endothelial cells. , 1997, The Journal of biological chemistry.
[79] C. A. Thomas,et al. Molecular cloning. , 1977, Advances in pathobiology.
[80] T.W.T. Dillon,et al. What Is a Complex , 1943 .