Pediatric Eosinophilic Granuloma in the Skull after Minor Head Trauma: A Case Report

Corresponding author: Hee Sup Shin Department of Neurosurgery, KyungHee University Hospital at Gangdong, Kyung Hee University School of Medicine, 892 Dongnam-ro, Gangdong-gu, Seoul 05278, Republic of Korea Tel: +82-2-440-6090 Fax: +82-2-440-8404 E-mail: realeponym@hanmail.net Here, we report a case of eosinophilic granuloma (EG) of the skull in a pediatric patient after minor head trauma without hemorrhage or fracture. A 15-year-old boy presented with a soft mass on the left side of his forehead. The mass was 2 cm in size and was associated with tenderness. It had grown rapidly in 1 month. He had been hit by a baseball on the left side of his forehead 9 months before. Cerebral computed tomography revealed a 2-cm-sized mass in the frontal bone region on the left side with a lytic bony defect. This mass was wellenhanced on cerebral magnetic resonance imaging, and the margin was well-demarcated without intracerebral infiltration. The mass was removed surgically. Total excision was performed through craniectomy around the mass, and the bony defect was reconstructed using bone cement. Three years postoperatively, there was no local or distant recurrence. Minor trauma without hemorrhage or fracture can trigger the development of EG. In pediatric patients, clinicians should be aware of a possible association between solitary EG of the skull and minor head trauma.

[1]  K. Jo,et al.  Rapid Growing Eosinophilic Granuloma in Skull after Minor Trauma , 2015, Korean journal of neurotrauma.

[2]  J. Ragheb,et al.  Nonoperative management of solitary eosinophilic granulomas of the calvaria. , 2013, Journal of neurosurgery. Pediatrics.

[3]  A. Hasturk,et al.  Multifocal extradural and intradural eosinophilic granuloma. , 2013, The Journal of craniofacial surgery.

[4]  I. Pajić-Penavić,et al.  Eosinophilic granuloma of the temporal bone in an adult: controversies in the management. , 2012, Collegium antropologicum.

[5]  D. Prayer,et al.  Incidence and pattern of radiological central nervous system Langerhans cell histiocytosis in children: A population based study , 2011, Pediatric blood & cancer.

[6]  N. Gupta,et al.  Eosinophilic granuloma of skull bone , 2009, Journal of cytology.

[7]  J. Smirniotopoulos,et al.  From the Archives of the AFIP. Pediatric orbit tumors and tumorlike lesions: osseous lesions of the orbit. , 2008, Radiographics : a review publication of the Radiological Society of North America, Inc.

[8]  Yong-sook Park,et al.  Eosinophilic granuloma presenting as an epidural hematoma and cyst. , 2008, Journal of Korean Neurosurgical Society.

[9]  Seong-Hyun Park,et al.  Eosinophilic Granuloma of the Skull: A Retrospective Analysis , 2007, Pediatric Neurosurgery.

[10]  B. Sandstedt,et al.  Long‐term follow‐up of Langerhans cell histiocytosis: 39 years’ experience at a single centre , 2005 .

[11]  G. Saigal,et al.  Langerhans’ cell histiocytosis: pathology, imaging and treatment of skeletal involvement , 2005, Pediatric Radiology.

[12]  J. Martínez-Lage,et al.  Solitary eosinophilic granuloma of the pediatric skull and spine , 1991, Child's Nervous System.

[13]  John Wu,et al.  Spontaneous Resolution of Calvarial Eosinophilic Granuloma in Children , 2003, Pediatric Neurosurgery.

[14]  M. Guelfguat,et al.  Langerhans' cell histiocytosis , 2003, The Lancet.

[15]  J. Martínez-Lage,et al.  Epidural hematoma from a cranial eosinophilic granuloma , 2002, Child's Nervous System.

[16]  C. Zuppan,et al.  Langerhans' cell histiocytosis presenting with an intracranial epidural hematoma , 2000, Pediatric Radiology.

[17]  R. Wilkins,et al.  Solitary eosinophilic granuloma of the skull. , 1984, Neurosurgery.

[18]  C. Arseni,et al.  Cranial eosinophilic granuloma. , 1977, Neurochirurgia.

[19]  S. Manaka,et al.  Skull tumor simulating sinus pericranii. Case report. , 1977, Journal of neurosurgery.

[20]  R. Knighton,et al.  Diagnosis and treatment of eosinophilic granuloma of skull. , 1956 .