Ureteroscopic biopsy of upper tract urothelial carcinoma and role of urinary biomarkers

Ureteroscopic biopsy is an integral part of diagnosis of urothelial carcinoma of the upper urinary tract. It can be a technical challenge, but diagnostic rates have improved remarkably with refinements in surgical technique and specimen processing. Cytology aids with diagnosis and other urinary biomarkers continue to evolve, which may help further stratify patients for treatment. The current literature on the ureteroscopic biopsy and role of urinary biomarkers is reviewed and summarized below.

[1]  A. Chinnaiyan,et al.  The utility of upper urinary tract urine cytology before and after application of the Paris system , 2018, Diagnostic cytopathology.

[2]  G. Netto,et al.  Diagnostic potential of TERT promoter and FGFR3 mutations in urinary cell‐free DNA in upper tract urothelial carcinoma , 2019, Cancer science.

[3]  M. Miyake,et al.  Emerging biomarkers for the diagnosis and monitoring of urothelial carcinoma , 2018, Research and reports in urology.

[4]  A. Breda,et al.  Comparison of biopsy devices in upper tract urothelial carcinoma , 2018, World Journal of Urology.

[5]  Chien-Feng Li,et al.  The diagnostic ureteroscopy before radical nephroureterectomy in upper urinary tract urothelial carcinoma is not associated with higher intravesical recurrence , 2018, World Journal of Surgical Oncology.

[6]  Xueying Li,et al.  Detection of urothelial carcinoma, upper tract urothelial carcinoma, bladder carcinoma, and urothelial carcinoma with gross hematuria using selected urine-DNA methylation biomarkers: A prospective, single-center study. , 2018, Urologic oncology.

[7]  V. Margulis,et al.  Multi-institutional Evaluation of Upper Urinary Tract Biopsy Using Backloaded Cup Biopsy Forceps, a Nitinol Basket, and Standard Cup Biopsy Forceps. , 2018, Urology.

[8]  J. Heymann,et al.  Improved correlation of urinary cytology specimens using The Paris System in biopsy‐proven upper tract urothelial carcinomas , 2018, Cancer cytopathology.

[9]  V. Margulis,et al.  Discordance between Ureteroscopic Biopsy and Final Pathology for Upper Tract Urothelial Carcinoma , 2018, The Journal of urology.

[10]  Xuesong Li,et al.  Impact of ureteroscopy before radical nephroureterectomy for upper tract urothelial carcinomas on oncological outcomes: a meta‐analysis , 2018, BJU international.

[11]  D. Chhieng,et al.  The Paris System for urine cytology in upper tract urothelial specimens: A comparative analysis with biopsy and surgical resection , 2018, Cytopathology : official journal of the British Society for Clinical Cytology.

[12]  M. Babjuk,et al.  European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2017 Update. , 2015, European urology.

[13]  C. Lallas,et al.  Endoscopic Treatment of Upper Tract Urothelial Carcinoma , 2017, Current Urology Reports.

[14]  S. Bhayani,et al.  Diagnostic Utility of Selective Upper Tract Urinary Cytology: A Systematic Review and Meta-analysis of the Literature. , 2016, Urology.

[15]  M. Quek,et al.  The Paris System for Reporting Urinary Cytology: The Quest to Develop a Standardized Terminology , 2016, Acta Cytologica.

[16]  S. Bhayani,et al.  Is Ureteroscopy Needed Prior to Nephroureterectomy? An Evidence-Based Algorithmic Approach. , 2016, Urology.

[17]  K. Ahrar,et al.  Safety and diagnostic accuracy of percutaneous biopsy in upper tract urothelial carcinoma , 2015, BJU international.

[18]  M. Grasso,et al.  Upper Urinary Tract Urothelial Carcinoma , 2015 .

[19]  L. Antunes,et al.  Accurate detection of upper tract urothelial carcinoma in tissue and urine by means of quantitative GDF15, TMEFF2 and VIM promoter methylation. , 2014, European journal of cancer.

[20]  A. Shabsigh,et al.  Utility and diagnostic accuracy of ureteroscopic biopsy in upper tract urothelial carcinoma. , 2013, Archives of pathology & laboratory medicine.

[21]  M. Bibbo,et al.  Ureteroscopic biopsy of upper tract urothelial carcinoma: comparison of basket and forceps. , 2013, Journal of endourology.

[22]  M. Bibbo,et al.  Voided urine fluorescence in situ hybridization testing for upper tract urothelial carcinoma surveillance. , 2010, The Journal of urology.

[23]  N. Theocharopoulos,et al.  Performance of computed tomographic urography in diagnosis of upper urinary tract urothelial carcinoma, in patients presenting with hematuria: Systematic review and meta-analysis. , 2010, European journal of radiology.

[24]  F. Algaba,et al.  Utility of fluorescence in situ hybridization as a non-invasive technique in the diagnosis of upper urinary tract urothelial carcinoma. , 2007, European urology.

[25]  M. Grasso,et al.  Advanced ureteroscopy: wireless and sheathless. , 2006, Journal of endourology.

[26]  Richard H Cohan,et al.  MDCT urography of upper tract urothelial neoplasms. , 2005, AJR. American journal of roentgenology.

[27]  R. Jenkins,et al.  The development of a multitarget, multicolor fluorescence in situ hybridization assay for the detection of urothelial carcinoma in urine. , 2000, The Journal of molecular diagnostics : JMD.

[28]  M. Bibbo,et al.  Ureteroscopic biopsy: technique and specimen preparation. , 1997, Urology.

[29]  M. Bibbo,et al.  Diagnostic accuracy of ureteroscopic biopsy in upper tract transitional cell carcinoma. , 1997, The Journal of urology.