Annotation: Psychopathology in Children with Intellectual Disability

Recent advances are reviewed in understanding the heightened prevalence of psychopathology and maladaptive behavior among children with intellectual disability. Researchers have traditionally emphasized measurement and prevalence issues, using either psychiatric assessments or rating scales to identify the prevalence of various problems in children with intellectual disability. Yet the time is ripe to shift directions, and identify more precisely why children are at increased risk for psychopathology to begin with. Although several “bio- psycho-social” hypotheses are reviewed, a particularly promising line of work links psychopathology to genetic intellectual disability syndromes. Psychiatric vulnerabilities in several syndromes are reviewed, as are the advantages of phenotypic work for understanding psychopathology among children with intellectual disability more generally.

[1]  B. Tonge,et al.  Population prevalence of psychopathology in children and adolescents with intellectual disability: II. Epidemiological findings. , 1996, Journal of intellectual disability research : JIDR.

[2]  R. Hodapp,et al.  Mental retardation's two cultures of behavioral research. , 1994, American journal of mental retardation : AJMR.

[3]  C. Donnelly Handbook of Neurodevelopmental and Genetic Disorders in Children , 2002 .

[4]  A. Brereton,et al.  Manual for the Developmental Behaviour Checklist: Primary Carer Version (DBC-P) and Teacher Version (DBC-T) (2nd ed.) , 2002 .

[5]  J. Matson,et al.  Depression in mentally retarded children. , 1988, Research in developmental disabilities.

[6]  E. Dykens Measuring behavioral phenotypes: provocations from the "new genetics". , 1995, American journal of mental retardation : AJMR.

[7]  B. Wolf,et al.  Psychomotor development in 65 home-reared children with cri-du-chat syndrome. , 1980, The Journal of pediatrics.

[8]  P. Howlin,et al.  Independence and adaptive behavior in adults with Williams syndrome. , 1997, American journal of medical genetics.

[9]  P. Sturmey,et al.  Validity of the Reiss Screen for Maladaptive Behavior. , 1994, American journal of mental retardation : AJMR.

[10]  B. Tonge,et al.  Behavioral and emotional disturbance in individuals with Williams syndrome. , 1997, American journal of mental retardation : AJMR.

[11]  A. Gath Down syndrome children and their families. , 2005, American journal of medical genetics. Supplement.

[12]  F. Volkmar,et al.  Annotation: childhood disorders in DSM-IV. , 1996, Journal of child psychology and psychiatry, and allied disciplines.

[13]  A. H. Reid,et al.  Psychiatric disorders in mentally handicapped children: a clinical and follow-up study. , 2008, Journal of mental deficiency research.

[14]  S. Greenspan,et al.  Reconsidering the construct of mental retardation: implications of a model of social competence. , 1992, American journal of mental retardation : AJMR.

[15]  R. Hodapp,et al.  Stress and coping in families of children with Smith-Magenis syndrome. , 2002, Journal of intellectual disability research : JIDR.

[16]  J. Jacobson Do some mental disorders occur less frequently among persons with mental retardation? , 1990, American journal of mental retardation : AJMR.

[17]  H. Boer,et al.  Problem behaviors associated with deletion Prader-Willi, Smith-Magenis, and cri du chat syndromes. , 1998, American journal of mental retardation : AJMR.

[18]  M. Feldman,et al.  Stress in Mothers with Intellectual Disabilities , 1997 .

[19]  Bengt Muthén,et al.  LONGITUDINAL STUDIES OF ACHIEVEMENT GROWTH USING LATENT VARIABLE MODELING , 1998 .

[20]  D. Dawson,et al.  Behavior problems of young girls with fragile X syndrome: factor scores on the Conners' Parent's Questionnaire. , 1994, American journal of medical genetics.

[21]  B. King Self-injury by people with mental retardation: a compulsive behavior hypothesis. , 1993, American journal of mental retardation : AJMR.

[22]  L. Koegel,et al.  Positive Behavioral Support: Including People with Difficult Behavior in the Community. , 1996 .

[23]  K. Cornish,et al.  Developmental and behavioural characteristics of cri du chat syndrome. , 1996, Archives of disease in childhood.

[24]  M. Aman Assessing Psychopathology and Behavior Problems in Persons with Mental Retardation: A Review of Available Instruments. , 1991 .

[25]  D. Harris,et al.  Evidence for a distinct region causing a cat-like cry in patients with 5p deletions. , 1995, American journal of human genetics.

[26]  Patricia Spallone,et al.  Hemizygosity at the elastin locus in a developmental disorder, Williams syndrome , 1993, Nature Genetics.

[27]  S. Larson,et al.  Challenging behaviors among persons with mental retardation in residential settings: Implications for policy, research, and practice , 1994 .

[28]  B. Pennington,et al.  Dimensions of shyness in fragile X females , 1995 .

[29]  M. Rutter,et al.  Research report: Isle of Wight Studies, 1964-1974. , 1976, Psychological medicine.

[30]  S. Reiss,et al.  Psychosocial correlates of depression in mentally retarded adults: I. Minimal social support and stigmatization. , 1985, American journal of mental deficiency.

[31]  B. Oostra,et al.  FMRP expression as a potential prognostic indicator in fragile X syndrome. , 1999, American journal of medical genetics.

[32]  B. King,et al.  Obsessive-compulsive symptoms in Prader-Willi and "Prader-Willi-Like" patients. , 1999, Journal of the American Academy of Child and Adolescent Psychiatry.

[33]  E. Dykens,et al.  Correlates of maladaptive behavior in individuals with 5p‐(cri du chat) syndrome , 1997, Developmental medicine and child neurology.

[34]  M Davies,et al.  Adults with Williams syndrome , 1998, British Journal of Psychiatry.

[35]  R. Hodapp,et al.  Craniofacial maturity and perceived personality in children with Down syndrome. , 1999, American journal of mental retardation : AJMR.

[36]  R. Archilla [Epilepsy and learning disabilities]. , 1997, Revista de neurologia.

[37]  R. Göstason Psychiatric Illness Among the Mentally Retarded: A Swedish population study , 1985, Acta Psychiatrica Scandinavica Supplementum.

[38]  F. Greenberg,et al.  Sleep disturbance in Smith-Magenis syndrome (del 17 p11.2). , 1998, American journal of medical genetics.

[39]  E. K. Turner,et al.  FETAL ALCOHOL SYNDROME , 1978, Paediatrics & child health.

[40]  G N Siperstein,et al.  The quality of friendships between children with and without learning problems. , 1997, American journal of mental retardation : AJMR.

[41]  J. Jacobson Problem behavior and psychiatric impairment within a developmentally disabled population I: behavior frequency. , 1982, Applied research in mental retardation.

[42]  D. Clarke Prader-Willi syndrome and psychotic symptoms: 2. A preliminary study of prevalence using the Psychopathology Assessment Schedule for Adults with Developmental Disability checklist. , 1998, Journal of Intellectual Disability Research.

[43]  E. Dykens Direct Effects of Genetic Mental Retardation Syndromes: Maladaptive Behavior and Psychopathology , 1999 .

[44]  E. Haan,et al.  Clinical features in four patients with Angelman syndrome resulting from paternal uniparental disomy. , 1997, Journal of medical genetics.

[45]  A. Reiss,et al.  The neurobiology of fragile X syndrome , 1995 .

[46]  S. Cooper,et al.  Differential Rates of Psychiatric Disorders in Adults with Down's Syndrome Compared with Other Mentally Handicapped Adults , 1992, British Journal of Psychiatry.

[47]  B. Finucane,et al.  The Spasmodic Upper‐body Squeeze: a Chalacteristic Behavior in Smith‐Magenis Syndrome , 1994, Developmental medicine and child neurology.

[48]  R. Sovner Limiting factors in the use of DSM-III criteria with mentally ill/mentally retarded persons. , 1986, Psychopharmacology bulletin.

[49]  A L Reiss,et al.  Specification of the neurobehavioral phenotype in males with fragile X syndrome. , 1995, Pediatrics.

[50]  R. Hodapp,et al.  Families of Children with Prader-Willi Syndrome: Stress-Support and Relations to Child Characteristics , 1997, Journal of autism and developmental disorders.

[51]  E. Dykens,et al.  Refining behavioral phenotypes: personality-motivation in Williams and Prader-Willi syndromes. , 1999, American journal of mental retardation : AJMR.

[52]  S. Cooper,et al.  Affective psychosis and Prader-Willi syndrome. , 1998, Journal of intellectual disability research : JIDR.

[53]  M. Rutter,et al.  Genetics and child psychiatry: II Empirical research findings. , 1999, Journal of child psychology and psychiatry, and allied disciplines.

[54]  C. Kasari,et al.  Maladaptive behavior in children with Prader-Willi syndrome, Down syndrome, and nonspecific mental retardation. , 1997, American journal of mental retardation : AJMR.

[55]  Karen Wills Neuropsychological Functioning in Children With Spina Bifida and/or Hydrocephalus , 1993 .

[56]  C. Kasari,et al.  Friendships in Children with Developmental Disabilities. , 1998 .

[57]  J. Bregman,et al.  Current developments in the understanding of mental retardation. Part II: Psychopathology. , 1991, Journal of the American Academy of Child and Adolescent Psychiatry.

[58]  J. Leckman,et al.  Obsessions and compulsions in Prader-Willi syndrome. , 1996, Journal of child psychology and psychiatry, and allied disciplines.

[59]  K. Cornish,et al.  Face recognition and emotion perception in boys with fragile-X syndrome. , 1998, Journal of intellectual disability research : JIDR.

[60]  B. Tonge,et al.  Diagnosis of Mental Disorders in People with Mental Retardation , 1998 .

[61]  S. Reiss Prevalence of dual diagnosis in community-based day programs in the Chicago metropolitan area. , 1990, American journal of mental retardation : AJMR.

[62]  Winston R. Sieck,et al.  Maltreatment in psychiatrically hospitalized children and adolescents with developmental disabilities: prevalence and correlates. , 1994, Journal of the American Academy of Child and Adolescent Psychiatry.

[63]  N. Schupf,et al.  Aging and Alzheimer Disease in People with Mental Retardation , 1993 .

[64]  P. Hindley Psychiatric aspects of hearing impairments. , 1997, Journal of child psychology and psychiatry, and allied disciplines.

[65]  S. Pueschel,et al.  Psychiatric Disorders in Persons with Down Syndrome , 1991, The Journal of nervous and mental disease.

[66]  R. Hodapp Development and Disabilities: Intellectual, Sensory and Motor Impairments , 1998 .

[67]  D. Goldberg,et al.  Respondent and informant accounts of psychiatric symptoms in a sample of patients with learning disability. , 1996, Journal of intellectual disability research : JIDR.

[68]  R. Hodapp,et al.  Families of children with 5p‐ (cri du chat) syndrome: familial stress and sibling reactions , 1997, Developmental medicine and child neurology.

[69]  David H. Warren,et al.  Blindness and children: Social–emotional and communicative development in infancy , 1994 .

[70]  R. Eyman,et al.  Who are the dually diagnosed? , 1990, American journal of mental retardation : AJMR.

[71]  R. Hodapp,et al.  Treatment issues in genetic mental retardation syndromes. , 1997 .

[72]  M. Gulley,et al.  Neurobehavioral characteristics of CGG amplification status in fragile X females. , 1994, American journal of medical genetics.

[73]  Michelle G. Craske,et al.  Anxiety Disorders: Psychological Approaches To Theory And Treatment , 1998 .

[74]  A. Gosch,et al.  Personality characteristics and behaviour problems in individuals of different ages with Williams syndrome , 1997, Developmental medicine and child neurology.

[75]  J. Leckman,et al.  Behavior and Development in Fragile X Syndrome , 1993 .

[76]  E. Dykens,et al.  Distinctiveness and correlates of maladaptive behaviour in children and adolescents with Smith-Magenis syndrome. , 1998, Journal of intellectual disability research : JIDR.