A Pyridine-Containing Cu2+-Selective Probe Based on Naphthalimide Derivative

A new fluorescent probe P derived from naphthalimide bearing a pyridine group has been synthesized and characterized. The proposed probe P shows high selectivity and sensitivity to Cu2+ in aqueous media. Under optimized conditions, the linear response of P (2 μM) toward Cu2+ was 0.05–0.9 μM in ethanol-water solution (3:2, v:v, 50 mM HEPES, pH 7.4), and the detection limit was 0.03 μM.

[1]  David R. Spring,et al.  Ratiometric fluorescent and colorimetric sensors for Cu2+ based on 4,5-disubstituted-1,8-naphthalimide and sensing cyanide via Cu2+ displacement approach , 2010 .

[2]  Limin Wang,et al.  Highly selective fluorescence turn-on chemosensor based on naphthalimide derivatives for detection of copper(II) ions. , 2013, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

[3]  Jun Zhang,et al.  Synthesis of a Cu2+-Selective Probe Derived from Rhodamine and Its Application in Cell Imaging , 2014, Sensors.

[4]  Jun Zhang,et al.  Fluorescent probe for copper(II) ion based on a rhodamine spirolactame derivative, and its application to fluorescent imaging in living cells , 2011 .

[5]  Xiaofeng Zhu,et al.  A BODIPY-based "turn-on" fluorescent and colorimetric sensor for selective detection of Cu2+ in aqueous media and its application in cell imaging , 2014 .

[6]  Lei Ding,et al.  Sulfonyl rhodamine hydrazide: A sensitive and selective chromogenic and fluorescent chemodosimeter for copper ion in aqueous media , 2011 .

[7]  Xin Lv,et al.  Highly sensitive and selective turn-on fluorescent and chromogenic probe for Cu2+ and ClO- based on a N-picolinyl rhodamine B-hydrazide derivative. , 2011, Organic & biomolecular chemistry.

[8]  Feng Liu,et al.  Copper ion-selective fluorescent sensor based on the inner filter effect using a spiropyran derivative. , 2005, Analytical chemistry.

[9]  Suk-Kyu Chang,et al.  The synthesis of crown ether-appended dichlorofluoresceins and their selective Cu2+ chemosensing , 2009 .

[10]  Carl Redshaw,et al.  Rhodamine-Triazine Based Probes for Cu2+ in Aqueous Media and Living Cells. , 2014 .

[11]  Jun Zhang,et al.  Copper(II)‐Responsive “Off‐On” Chemosensor Based on a Naphthalimide Derivative , 2014 .

[12]  Gopal Das,et al.  NIR- and FRET-based sensing of Cu2+ and S2- in physiological conditions and in live cells. , 2013, Inorganic chemistry.

[13]  Mingming Hu,et al.  A fluorescent ratiometric chemodosimeter for Cu2+ based on TBET and its application in living cells. , 2013, Organic letters.

[14]  Juyoung Yoon,et al.  A naphthalimide-calixarene as a two-faced and highly selective fluorescent chemosensor for Cu2+ or F- , 2007 .

[15]  Lin Xu,et al.  A naphthalimide-based bifunctional fluorescent probe for the differential detection of Hg²⁺ and Cu²⁺ in aqueous solution. , 2014, Dalton transactions.

[16]  Min Xu,et al.  A new rhodamine-based chemosensor for Cu2+ and the study of its behaviour in living cells. , 2010, Dalton transactions.

[17]  Jun Zhang,et al.  A selective fluorescent chemosensor with 1, 2, 4-triazole as subunit for Cu (II) and its application in imaging Cu (II) in living cells , 2012 .

[18]  Dylan W Domaille,et al.  Metals in neurobiology: probing their chemistry and biology with molecular imaging. , 2008, Chemical reviews.

[19]  Fang Wang,et al.  Fluorescence turn on of coumarin derivatives by metal cations: a new signaling mechanism based on C=N isomerization. , 2007, Organic letters.

[20]  Sun Young Park,et al.  FRET-derived ratiometric fluorescence sensor for Cu2+ , 2008 .

[21]  Juyoung Yoon,et al.  New fluorescent and colorimetric chemosensors bearing rhodamine and binaphthyl groups for the detection of Cu2 , 2009 .

[22]  Guo-Li Shen,et al.  Highly sensitive and selective colorimetric and off-on fluorescent chemosensor for Cu2+ in aqueous solution and living cells. , 2009, Analytical chemistry.

[23]  Lin Yuan,et al.  Construction of fluorescent probes via protection/deprotection of functional groups: a ratiometric fluorescent probe for Cu2+. , 2009, Chemistry.

[24]  Yu Zhou,et al.  A colorimetric probe for copper(II) ion based on 4-amino-1,8-naphthalimide , 2012 .

[25]  Jun Zhang,et al.  "Off-On" based fluorescent chemosensor for Cu2+ in aqueous media and living cells. , 2011, Talanta.

[26]  Jun Zhang,et al.  Highly sensitive and selective colorimetric and off-on fluorescent probe for Cu(2+) based on rhodamine derivative. , 2010, Organic & biomolecular chemistry.

[27]  Feng Feng,et al.  A Coumarin-Derived Fluorescence Chemosensors Selective for Copper(II) , 2008 .