Epthelial Myoepithelial Carcinoma : A Rare Salivary Gland Neoplasm

Objective: Epithelial-Myoepithelial Carcinoma is a rare entity with an incidence of <0.5% of all salivary gland neoplasms. Parotid gland is the commonest affected site(75%) followed by submandibular gland(12%) and minor glands in palate(7%). Women, usually in seventh decade of life, are commonly affected. These tumors can recur locally following resection. Epithelial-Myoepithelial carcinoma presents as a solitary, bulky mass which gradually enlarges over several months. This tumor is biphasic; composed of double layered ducts having an inner lining of small cuboidal or low columnar cells i.e. epithelial component and an outer mantle of clear cells i.e. myoepithelial component. Epithelial-Myoepithelial Carcinoma of salivary gland is a low-grade malignancy with distinct morphological features, and requires a wider recognition for better management. Case Report: We describe a case of male patient who presented with a swelling behind the left ear and was clinically diagnosed as Pleomorphic adenoma of the parotid gland. On FNAC, a differential of Adenoid Cystic Carcinoma or Epithelial-Myoepithelial Carcinoma of parotid gland were given. Histo-pathology revealed Epithelial-Myoepithelial Carcinoma which was corroborated with Immunohistochemistry. Conclusion: Epithelial-Myoepithelial Carcinoma is often misdiagnosed. Hence, a thorough pathological work-up is essential for establishing definite diagnosis so as to enable to execute appropriate and complete treatment.