Strategies to identify ion channel modulators: current and novel approaches to target neuropathic pain.
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L. Dekker | Phillip J Birch | Lodewijk V Dekker | Iain F James | Andrew Southan | David Cronk | P. J. Birch | I. James | A. Southan | D. Cronk
[1] W. Stühmer,et al. Calcium channel characteristics conferred on the sodium channel by single mutations , 1992, Nature.
[2] W. Catterall. Structure and function of voltage-gated ion channels. , 1995, Annual review of biochemistry.
[3] L. Sivilotti,et al. A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons , 1996, Nature.
[4] P. Powers,et al. Absence of the β subunit (cchb1) of the skeletal muscle dihydropyridine receptor alters expression of the α1 subunit and eliminates excitation-contraction coupling , 1996 .
[5] K. Bley,et al. Tetrodotoxin inhibits neuropathic ectopic activity in neuromas, dorsal root ganglia and dorsal horn neurons , 1997, PAIN.
[6] R Y Tsien,et al. Improved indicators of cell membrane potential that use fluorescence resonance energy transfer. , 1997, Chemistry & biology.
[7] S. McMahon,et al. Regulation of Expression of the Sensory Neuron-Specific Sodium Channel SNS in Inflammatory and Neuropathic Pain , 1997, Molecular and Cellular Neuroscience.
[8] R. Eglen,et al. Distribution of the Tetrodotoxin-Resistant Sodium Channel PN3 in Rat Sensory Neurons in Normal and Neuropathic Conditions , 1998, The Journal of Neuroscience.
[9] B. Chait,et al. The structure of the potassium channel: molecular basis of K+ conduction and selectivity. , 1998, Science.
[10] Brian Cox,et al. HTS approaches to voltage-gated ion channel drug discovery , 1998 .
[11] R. LaMotte,et al. Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain , 1999, PAIN®.
[12] E. Mccleskey. Calcium Channel Permeation: A Field in Flux , 1999, The Journal of general physiology.
[13] J. Jen. Calcium channelopathies in the central nervous system , 1999, Current Opinion in Neurobiology.
[14] G. Terstappen,et al. Functional analysis of native and recombinant ion channels using a high-capacity nonradioactive rubidium efflux assay. , 1999, Analytical biochemistry.
[15] S. Boyce,et al. The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways , 1999, Nature Neuroscience.
[16] T. Carlstedt,et al. Immunolocalization of SNS/PN3 and NaN/SNS2 sodium channels in human pain states , 2000, Pain.
[17] W. Catterall. Structure and regulation of voltage-gated Ca2+ channels. , 2000, Annual review of cell and developmental biology.
[18] Gail Mandel,et al. Nomenclature of Voltage-Gated Sodium Channels , 2000, Neuron.
[19] K Mizuguchi,et al. beta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[20] S. Waxman,et al. The neuron as a dynamic electrogenic machine: modulation of sodium-channel expression as a basis for functional plasticity in neurons. , 2000, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
[21] S. McMahon,et al. A role for the TTX-resistant sodium channel Nav 1.8 in NGF-induced hyperalgesia, but not neuropathic pain , 2001, Neuroreport.
[22] B. Hille,et al. Ionic channels of excitable membranes , 2001 .
[23] Lei Wu,et al. Ion-channel assay technologies: quo vadis? , 2001, Drug discovery today.
[24] R. Greenberg,et al. Phylogeny of ion channels: clues to structure and function. , 2001, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.
[25] J. Chung,et al. The changes in expression of three subtypes of TTX sensitive sodium channels in sensory neurons after spinal nerve ligation. , 2001, Brain research. Molecular brain research.
[26] L. Isom. Sodium Channel β Subunits: Anything but Auxiliary , 2001 .
[27] Roderick MacKinnon,et al. Energetic optimization of ion conduction rate by the K+ selectivity filter , 2001, Nature.
[28] G. Tomaselli,et al. Molecular Architecture of the Voltage-Dependent Na Channel , 2001, The Journal of general physiology.
[29] M. Gold,et al. Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8 , 2002, Pain.
[30] E. Stefani,et al. Aging, ion channel expression, and vascular function. , 2002, Vascular pharmacology.
[31] M. Chao,et al. Annexin II light chain regulates sensory neuron-specific sodium channel expression , 2002, Nature.
[32] Andreas Sewing,et al. High-Throughput Screening for Ion Channel Modulators , 2002, Journal of biomolecular screening.
[33] C. Woolf,et al. Progressive tactile hypersensitivity after a peripheral nerve crush: non-noxious mechanical stimulus-induced neuropathic pain , 2002, Pain.
[34] Youxing Jiang,et al. The open pore conformation of potassium channels , 2002, Nature.
[35] S. Dib-Hajj,et al. Diverse functions and dynamic expression of neuronal sodium channels. , 2002, Novartis Foundation symposium.
[36] Youxing Jiang,et al. Crystal structure and mechanism of a calcium-gated potassium channel , 2002, Nature.
[37] William A Catterall,et al. Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel β2-subunits , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[38] C. Peers. Hypoxic regulation of ion channel function and expression , 2002, Experimental physiology.
[39] Samuel F. Berkovic,et al. Channelopathies as a genetic cause of epilepsy. , 2003 .
[40] Youxing Jiang,et al. The principle of gating charge movement in a voltage-dependent K+ channel , 2003, Nature.
[41] S. Waxman,et al. Upregulation of Sodium Channel Nav1.3 and Functional Involvement in Neuronal Hyperexcitability Associated with Central Neuropathic Pain after Spinal Cord Injury , 2003, The Journal of Neuroscience.
[42] P. Christophersen,et al. High throughput electrophysiology: new perspectives for ion channel drug discovery. , 2003, Receptors & channels.
[43] Derek J Trezise,et al. IonWorks™ HT: A New High-Throughput Electrophysiology Measurement Platform , 2003, Journal of biomolecular screening.
[44] Rafael J. Taboryski,et al. Upscaling and Automation of Electrophysiology: Toward High Throughput Screening in Ion Channel Drug Discovery , 2003 .
[45] U. Warrior,et al. Functional analysis of large conductance Ca2(+)-activated K(+) channels: ion flux studies by atomic absorption spectrometry. , 2003, Assay and drug development technologies.
[46] P. Chatelain,et al. Comparative Study of Membrane Potential-Sensitive Fluorescent Probes and their Use in Ion Channel Screening Assays , 2003, Journal of biomolecular screening.
[47] P. Distefano,et al. Sodium Channel β4, a New Disulfide-Linked Auxiliary Subunit with Similarity to β2 , 2003, The Journal of Neuroscience.
[48] D. Weinreich,et al. Redistribution of NaV1.8 in Uninjured Axons Enables Neuropathic Pain , 2003, The Journal of Neuroscience.
[49] M. Cadene,et al. X-ray structure of a voltage-dependent K+ channel , 2003, Nature.
[50] K. Campbell,et al. Auxiliary subunits: essential components of the voltage-gated calcium channel complex , 2003, Current Opinion in Neurobiology.
[51] Clay W Scott,et al. A medium-throughput functional assay of KCNQ2 potassium channels using rubidium efflux and atomic absorption spectrometry. , 2003, Analytical biochemistry.
[52] B. Zhorov,et al. Potassium, sodium, calcium and glutamate‐gated channels: pore architecture and ligand action , 2004, Journal of neurochemistry.