Trial and error. How to avoid commonly encountered limitations of published clinical trials.
暂无分享,去创建一个
[1] J. Wittes,et al. Analysis and interpretation of treatment effects in subgroups of patients in randomized clinical trials. , 1991, JAMA.
[2] Lawrence Joseph,et al. Placing trials in context using bayesian analysis: GUSTO revisited by Reverend Bayes , 1995 .
[3] D. Sackett,et al. The number needed to treat: a clinically useful measure of treatment effect , 1995, BMJ.
[4] M J Campbell,et al. Clinical significance not statistical significance: a simple Bayesian alternative to p values. , 1998, Journal of epidemiology and community health.
[5] Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction. , 1998, The New England journal of medicine.
[6] S. Goodman. Toward Evidence-Based Medical Statistics. 1: The P Value Fallacy , 1999, Annals of Internal Medicine.
[7] S. Yusuf,et al. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. , 2000 .
[8] S. Assmann,et al. Subgroup analysis and other (mis)uses of baseline data in clinical trials , 2000, The Lancet.
[9] C D Naylor,et al. Subgroups, treatment effects, and baseline risks: some lessons from major cardiovascular trials. , 2000, American heart journal.
[10] E. Braunwald,et al. Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein IIb/IIIa inhibitor tirofiban. , 2001, The New England journal of medicine.
[11] Jonathan A C Sterne,et al. Sifting the evidence—what's wrong with significance tests? , 2001, BMJ : British Medical Journal.
[12] The Time Investigators. Trial of invasive versus medical therapy in elderly patients with chronic symptomatic coronary-artery disease (TIME): a randomised trial , 2001, The Lancet.
[13] D. DeMets,et al. Principles from clinical trials relevant to clinical practice: Part I. , 2002, Circulation.
[14] Carl J Pepine,et al. ACC/AHA guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction--2002: summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients , 2002, Circulation.
[15] E. Boersma,et al. Platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: a meta-analysis of all major randomised clinical trials ☆ , 2002 .
[16] Robert M Califf,et al. Lessons learned from recent cardiovascular clinical trials: Part I. , 2002, Circulation.
[17] Catherine Sudlow,et al. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients , 2002, BMJ : British Medical Journal.
[18] Nick Freemantle,et al. Composite outcomes in randomized trials: greater precision but with greater uncertainty? , 2003, JAMA.
[19] Jeffrey W Moses,et al. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. , 2003, The New England journal of medicine.
[20] Sanjay Kaul,et al. Prior convictions: Bayesian approaches to the analysis and interpretation of clinical megatrials. , 2004, Journal of the American College of Cardiology.
[21] R. Califf,et al. Enoxaparin vs unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndromes managed with an intended early invasive strategy: primary results of the SYNERGY randomized trial. , 2004, JAMA.
[22] P. Rothwell. Subgroup analysis in randomised controlled trials: importance, indications, and interpretation , 2005, The Lancet.
[23] J. Tijssen,et al. Early invasive versus selectively invasive management for acute coronary syndromes. , 2005, The New England journal of medicine.
[24] G. Guyatt,et al. Validity of composite end points in clinical trials , 2005, BMJ : British Medical Journal.
[25] Marc A Pfeffer,et al. The charisma of subgroups and the subgroups of CHARISMA. , 2006, The New England journal of medicine.
[26] J. Habbema,et al. Subgroup analyses in therapeutic cardiovascular clinical trials: are most of them misleading? , 2006, American heart journal.
[27] S. Lagakos. The challenge of subgroup analyses--reporting without distorting. , 2006, The New England journal of medicine.
[28] Stephen W Lagakos,et al. Statistics in medicine--reporting of subgroup analyses in clinical trials. , 2007, The New England journal of medicine.
[29] E. Antman,et al. Prasugrel versus clopidogrel in patients with acute coronary syndromes. , 2007, The New England journal of medicine.
[30] J. Gebel. The CAPRIE-like subgroups of CHARISMA: a CAPRIEciously biased analysis of an unCHARISMAtic truth. , 2007, Journal of the American College of Cardiology.
[31] G. Guyatt,et al. Methodologic discussions for using and interpreting composite endpoints are limited, but still identify major concerns. , 2007, Journal of clinical epidemiology.
[32] X. Álvarez,et al. Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events , 2007 .
[33] Gordon H Guyatt,et al. Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled trials , 2007, BMJ : British Medical Journal.
[34] E. Antman,et al. A perspective on the efficacy and safety of intensive antiplatelet therapy in the trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel-thrombolysis in myocardial infarction 38. , 2008, The American journal of cardiology.
[35] E. Lesaffre. Superiority, equivalence, and non-inferiority trials. , 2008, Bulletin of the NYU hospital for joint diseases.
[36] Demosthenes B Panagiotakos,et al. The Value of p-Value in Biomedical Research , 2008, The open cardiovascular medicine journal.
[37] A. Rabinstein. Patients With Prior Myocardial Infarction, Stroke, or Symptomatic Peripheral Arterial Disease in the CHARISMA Trial , 2008 .
[38] D. Altman,et al. Composite Outcomes in Cardiovascular Research: A Survey of Randomized Trials , 2008, Annals of Internal Medicine.
[39] P. Teirstein. Percutaneous Revascularization Is the Preferred Strategy for Patients With Significant Left Main Coronary Stenosis , 2009, Circulation.
[40] B. Gersh,et al. The Problem With Composite End Points in Cardiovascular Studies: The Story of Major Adverse Cardiac Events and Percutaneous Coronary Intervention , 2009 .
[41] Seung‐Jung Park,et al. Percutaneous Coronary Intervention With Stent Implantation Versus Coronary Artery Bypass Surgery for Treatment of Left Main Coronary Artery Disease: Is It Time to Change Guidelines? , 2009, Circulation. Cardiovascular interventions.