The framework of toxicology information.

The scientific and societal underpinnings of toxicology are reviewed, as is the structure and flow of its information. Historical sources are presented, followed by a summary of patterns of publication in and access to the periodical, monographic, and special report literature. Computerized information is stressed and specialized systems such as TOXNET and CIS are described. Other innovative electronic projects, including micro-CSIN and the ANSWER workstation are touched upon. Important organizations active in the toxicology field are highlighted and information applications in the legislative, regulatory, and judicial areas are discussed. Finally, the work of international organizations is reviewed and new directions in toxicology information are explored.

[1]  D. Raitt,et al.  The evolution and development of the International Online Information Meetings , 1989 .

[2]  A. Cawkell.  Evolution of an information society , 1987 .

[3]  Robert Lee Chartrand.  Public laws and public access , 1987, Inf. Soc..

[4]  Philip Wexler,et al.  Toxicology information systems: a historical perspective , 1985, J. Chem. Inf. Comput. Sci..

[5]  D K Burns,et al.  The HSE National Exposure Database--(NEDB). , 1989, The Annals of occupational hygiene.

[6]  David Bawden,et al.  Chemical toxicology databanks , 1988 .

[7]  H. Frumkin,et al.  The right to know about toxic exposures. Implications for physicians. , 1985, The New England journal of medicine.

[8]  Philip Wexler.  Information resources in toxicology , 1988 .

[9]  T. Litovitz,et al.  1986 annual report of the American Association of Poison Control Centers National Data Collection System. , 1987, The American journal of emergency medicine.

[10]  Michael D. Waters,et al.  The GENE-TOX Program: genetic activity evaluation , 1981, J. Chem. Inf. Comput. Sci..

[11]  K. Rest,et al.  Clinical industrial toxicology. An approach to information retrieval. , 1985, Annals of internal medicine.

[12]  R W O'Connor,et al.  Managing data quality through automation. , 1987, Toxicology.

[13]  R J Soto,et al.  Data base management system for tracking occupational health. , 1983, American Industrial Hygiene Association journal.

[14]  Legal standards of causation in chemical exposure litigation. , 1987, Regulatory toxicology and pharmacology : RTP.

[15]  D. M. Cipra,et al.  Safety: A guide to nearly 50 databases containing occupational, personal and other safety-related information , 1985 .

[16]  J. J. Fitzsimmons.  CommentThe information millennium , 1987, Inf. Soc..

[17]  T. Litovitz,et al.  1988 annual report of the American Association of Poison Control Centers National Data Collection System. , 1989, The American journal of emergency medicine.

[18]  W. Eckert.  Historical aspects of poisoning and toxicology. , 1981, The American journal of forensic medicine and pathology.

[19]  B Black,et al.  Evolving legal standards for the admissibility of scientific evidence. , 1988, Science.

[20]  Toby Adams.  Information technology R&D: Critical trends and issues: U.S. Office of Technology Assessment Washington, D.C.: U. S. Government Printing Office, 1985, 341 pages, $9.50 Y 3.T 22/2: 2In 3/3. S/N 052-003-00976-5. LC 84-601150 , 1986 .

[21]  T. Litovitz,et al.  Poison information providers: an assessment of proficiency. , 1984, The American journal of emergency medicine.

[22]  B. Källén.  Search for teratogenic risks with the aid of malformation registries. , 1987, Teratology.

[23]  B. J. Kostrewski,et al.  An evaluation of information sources in household product poisoning , 1986, J. Inf. Sci..

[24]  N. D. Agnish.  Design and Validation of Computer Software for Teratology and Reproductive Toxicology Studies , 1986 .

[25]  Krenzelok Ep,et al.  Microfiche vs. computerized Poisindex: the impact on time management. , 1988 .

[26]  K. Keeler.  Can we guarantee the safety of genetically engineered organisms in the environment? , 1988, Critical reviews in biotechnology.

[27]  J M Hushon.  Response to chemical emergencies. , 1986, Environmental science & technology.

[28]  Lisella Fs,et al.  Promising biotechnology industry raises unique safety, health issues. , 1988 .

[29]  B S Dean,et al.  Quality assurance: how it can help a poison information center. , 1988, Veterinary and human toxicology.

[30]  J M Frazier,et al.  Alternatives to animals in toxicity testing. , 1989, Scientific American.

[31]  A. Scialli.  A Computerized Consultation Service in Reproductive Toxicology: Summary of the First Five Years , 1988, Obstetrics and gynecology.

[32]  E. J. Burger.  Scientific information in judicial and administrative systems. , 1988, Social science & medicine.

[33]  Judith M. Hushon.  Expert systems for environmental problems , 1987 .

[34]  D M Halton.  Computerized Information Resources in Toxicology and Industrial Health-a Review , 1986, Toxicology and industrial health.

[35]  B L Oser,et al.  Toxicology then and now. , 1987, Regulatory toxicology and pharmacology : RTP.

[36]  H S Rosenkranz,et al.  Case, the Computer-Automated Structure Evaluation System, as an Alternative To Extensive Animal Testing , 1988, Toxicology and industrial health.

[37]  Reiner Luckenbach.  The free flow of information: an utopia? Ways to improve scientific and technological information and its international exchange , 1988, J. Chem. Inf. Comput. Sci..

[38]  E. Krenzelok,et al.  Personnel requirements of a poison information center. , 1987, American journal of hospital pharmacy.

[39]  J. S. Wassom,et al.  Use of selected toxicology information resources in assessing relationships between chemical structure and biological activity. , 1985, Environmental health perspectives.

[40]  S G Hadden.  Providing citizens with information about health effects of hazardous chemicals. , 1989, Journal of occupational medicine. : official publication of the Industrial Medical Association.