Stochastic Sensitivity Analysis for a Competitive Turbidostat Model with Inhibitory Nutrients

A stochastic model of turbidostat in which two microorganism species compete for an inhibitory growth-limiting nutrient is considered. In the deterministic case, the model has rich dynamics: a coexistence equilibrium and the washout equilibrium can be simultaneously stable, and a stable limit cycle may exist. In the stochastic case, a phenomenon of noise-induced extinction occurs. Namely, the stochastic trajectory near the deterministic coexistence equilibrium will tend to the washout equilibrium. Based on the stochastic sensitivity function technique, in this paper, we construct the confidence ellipse and then estimate the critical value of the intensity for noise generating a transition from coexistence to extinction. We also construct the confidence band to find the configurational arrangement of the stochastic cycle.

[1]  L. Ryashko,et al.  Stochastic sensitivity analysis of noise-induced excitement in a prey–predator plankton system , 2011 .

[2]  Irina Bashkirtseva,et al.  Stochastic Bifurcations and Noise-Induced Chaos in a Dynamic Prey-Predator Plankton System , 2014, Int. J. Bifurc. Chaos.

[3]  Sanling Yuan,et al.  Critical result on the break-even concentration in a single-species stochastic chemostat model , 2016 .

[4]  John F. Andrews,et al.  A mathematical model for the continuous culture of microorganisms utilizing inhibitory substrates , 1968 .

[5]  Jean-Luc Gouzé,et al.  Feedback control for nonmonotone competition models in the chemostat , 2005 .

[6]  Mark I. Nelson,et al.  A fundamental analysis of continuous flow bioreactor models and membrane reactor models to process industrial wastewaters , 2008 .

[7]  Competition between plasmid-bearing and plasmid-free organisms in a chemostat with nutrient recycling and an inhibitor. , 2006, Mathematical biosciences.

[8]  Paul Waltman,et al.  A survey of mathematical models of competition with an inhibitor. , 2004, Mathematical biosciences.

[9]  Paul Waltman,et al.  Competition between plasmid-bearing and plasmid-free organisms in a chemostat with an inhibitor , 2011, 2011 6th IEEE Joint International Information Technology and Artificial Intelligence Conference.

[10]  S. Ruan,et al.  Oscillations in plankton models with nutrient recycling. , 2001, Journal of theoretical biology.

[11]  Huaxing Xia,et al.  Transient oscillations induced by delayed growth response in the chemostat , 2005, Journal of mathematical biology.

[12]  L Ryashko,et al.  Sensitivity Analysis of Stochastic Attractors and Noise-induced Transitions for Population Model with Allee Effect Additional Information on Chaos Sensitivity Analysis of Stochastic Attractors and Noise-induced Transitions for Population Model with Allee Effect , 2022 .

[13]  L. Ryashko,et al.  Constructive analysis of noise-induced transitions for coexisting periodic attractors of the Lorenz model. , 2009, Physical review. E, Statistical, nonlinear, and soft matter physics.

[14]  D. Jiang,et al.  Competitive exclusion in a stochastic chemostat model with Holling type II functional response , 2016, Journal of Mathematical Chemistry.

[15]  G. Mil’shtein,et al.  A first approximation of the quasipotential in problems of the stability of systems with random non-degenerate perturbations , 1995 .

[16]  Tonghua Zhang,et al.  Asymptotic Behavior of a Chemostat Model with Stochastic Perturbation on the Dilution Rate , 2013 .

[17]  N. Panikov,et al.  Microbial Growth Kinetics , 1995 .

[18]  Yongli Song,et al.  Oscillations in a plasmid turbidostat model with delayed feedback control , 2011 .

[19]  Sanling Yuan,et al.  An analogue of break-even concentration in a simple stochastic chemostat model , 2015, Appl. Math. Lett..

[20]  Gail S. K. Wolkowicz,et al.  Competition in the Chemostat: A Distributed Delay Model and Its Global Asymptotic Behavior , 1997, SIAM J. Appl. Math..

[22]  Tewfik Sari,et al.  Global dynamics of the chemostat with different removal rates and variable yields. , 2011, Mathematical biosciences and engineering : MBE.

[23]  Donal O'Regan,et al.  The periodic solutions of a stochastic chemostat model with periodic washout rate , 2016, Commun. Nonlinear Sci. Numer. Simul..

[24]  Fabien Campillo,et al.  Stochastic modeling of the chemostat , 2011 .

[25]  Bingtuan Li Competition in a turbidostat for an inhibitory nutrient , 2008, Journal of biological dynamics.

[26]  W. Sokol,et al.  Kinetics of phenol oxidation by washed cells , 1981 .

[27]  Paul Waltman,et al.  The Theory of the Chemostat , 1995 .

[28]  Tonghua Zhang,et al.  Global analysis of continuous flow bioreactor and membrane reactor models with death and maintenance , 2012, Journal of Mathematical Chemistry.

[29]  Sergei S. Pilyugin,et al.  Feedback-mediated coexistence and oscillations in the chemostat , 2007 .

[30]  Tadayuki Hara,et al.  Delayed feedback control for a chemostat model. , 2006, Mathematical biosciences.

[31]  Dynamics of a plasmid chemostat model with periodic nutrient input and delayed nutrient recycling , 2012 .

[32]  Hal L. Smith,et al.  How Many Species Can Two Essential Resources Support? , 2001, SIAM J. Appl. Math..

[33]  Competition between microorganisms for a single limiting resource with cell quota structure and spatial variation , 2012, Journal of mathematical biology.

[34]  Shigui Ruan,et al.  Global Stability in Chemostat-Type Competition Models with Nutrient Recycling , 1998, SIAM J. Appl. Math..

[35]  Hal L. Smith,et al.  Feedback control for chemostat models , 2003, Journal of mathematical biology.

[36]  Irina A. Bashkirtseva,et al.  Confidence Domains in the Analysis of Noise-Induced Transition to Chaos for Goodwin Model of Business Cycles , 2014, Int. J. Bifurc. Chaos.

[37]  Sze-Bi Hsu,et al.  A Mathematical Model of the Chemostat with Periodic Washout Rate , 1985 .

[38]  L. Imhofa,et al.  Exclusion and persistence in deterministic and stochastic chemostat models , 2005 .

[39]  Bingtuan Li,et al.  Global Asymptotic Behavior of the Chemostat: General Response Functions and Different Removal Rates , 1998, SIAM J. Appl. Math..

[40]  Osamu Tagashira Permanent coexistence in chemostat models with delayed feedback control , 2009 .

[41]  Xinxin Wang,et al.  Competitive Exclusion in Delayed Chemostat Models with Differential Removal Rates , 2014, SIAM J. Appl. Math..

[42]  Guanrong Chen,et al.  Analysis of noise-induced transitions from regular to chaotic oscillations in the Chen system. , 2012, Chaos.