Near‐field photothermal microspectroscopy for adult stem‐cell identification and characterization

The identification of stem cells in adult tissue is a challenging problem in biomedicine. Currently, stem cells are identified by individual epitopes, which are generally tissue specific. The discovery of a stem‐cell marker common to other adult tissue types could open avenues in the development of therapeutic stem‐cell strategies.

[1]  Olav M. Kvalheim,et al.  Introduction to Factor‐Based Approaches , 2006 .

[2]  D. Powe,et al.  Morphological characteristics of the limbal epithelial crypt , 2006, British Journal of Ophthalmology.

[3]  J P Freyer,et al.  FTIR spectroscopy demonstrates biochemical differences in mammalian cell cultures at different growth stages. , 2003, Biophysical journal.

[4]  N. Koizumi,et al.  Amniotic Membrane as a Substrate for Cultivating Limbal Corneal Epithelial Cells for Autologous Transplantation in Rabbits , 2000, Cornea.

[5]  Jean Susini,et al.  Fourier Transform Infrared Microspectroscopy Identifies Symmetric PO2− Modifications as a Marker of the Putative Stem Cell Region of Human Intestinal Crypts , 2008, Stem cells.

[6]  Francis L Martin,et al.  Characterization of putative stem cell populations in the cornea using synchrotron infrared microspectroscopy. , 2006, Investigative ophthalmology & visual science.

[7]  Henry H. Mantsch,et al.  Infrared spectroscopy of biomolecules , 1996 .

[8]  W. Halliday,et al.  In situ characterization of beta-amyloid in Alzheimer's diseased tissue by synchrotron Fourier transform infrared microspectroscopy. , 1996, Biophysical journal.

[9]  W. McKinney,et al.  IR spectroscopic characteristics of cell cycle and cell death probed by synchrotron radiation based Fourier transform IR spectromicroscopy. , 2000, Biopolymers.

[10]  F. Watt,et al.  Stem cells: the generation and maintenance of cellular diversity. , 1989, Development.

[11]  G. Wilson,et al.  The effect of a shear force on the cell shedding rate of the corneal epithelium. , 2009, Acta ophthalmologica Scandinavica.

[12]  Hubert M. Pollock,et al.  Characterization of human corneal stem cells by synchrotron infrared micro-spectroscopy , 2007, Molecular vision.

[13]  T. Sun,et al.  Corneal epithelial stem cells: past, present, and future. , 2004, The journal of investigative dermatology. Symposium proceedings.

[14]  H. Pollock,et al.  Highly localized thermal, mechanical, and spectroscopic characterization of polymers using miniaturized thermal probes , 2000 .

[15]  A. Riggs,et al.  Dynamic reorganization of chromatin structure and selective DNA demethylation prior to stable enhancer complex formation during differentiation of primary hematopoietic cells in vitro. , 2004, Blood.

[16]  Tom Misteli,et al.  Chromatin in pluripotent embryonic stem cells and differentiation , 2006, Nature Reviews Molecular Cell Biology.

[17]  H. Meier,et al.  Spectroscopic Methods in Organic Chemistry , 2007 .

[18]  F. Keilmann Vibrational-infrared near-field microscopy , 2002 .

[19]  K. Georgopoulos Haematopoietic cell-fate decisions, chromatin regulation and ikaros , 2002, Nature Reviews Immunology.

[20]  Francis L Martin,et al.  Monitoring cell cycle distributions in MCF-7 cells using near-field photothermal microspectroscopy. , 2005, Biophysical journal.

[21]  Arun Brahma,et al.  Development of a three-dimensional organ culture model for corneal wound healing and corneal transplantation. , 2006, Investigative ophthalmology & visual science.

[22]  T. Inatomi,et al.  The use of autologous serum in the development of corneal and oral epithelial equivalents in patients with Stevens-Johnson syndrome. , 2006, Investigative ophthalmology & visual science.

[23]  T. Inatomi,et al.  Phenotypic investigation of human eyes with transplanted autologous cultivated oral mucosal epithelial sheets for severe ocular surface diseases. , 2007, Ophthalmology.

[24]  Francis L Martin,et al.  Infrared spectroscopy with multivariate analysis potentially facilitates the segregation of different types of prostate cell. , 2006, Biophysical journal.