A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region.
暂无分享,去创建一个
[1] B. Hemmings,et al. Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[2] B. Kemp,et al. Protein kinase recognition sequence motifs. , 1990, Trends in biochemical sciences.
[3] B. Mayer,et al. Binding of transforming protein, P47gag-crk, to a broad range of phosphotyrosine-containing proteins. , 1990, Science.
[4] H. Hanafusa,et al. Activation of the proto-oncogene p60c-src by point mutations in the SH2 domain , 1990, Molecular and cellular biology.
[5] B. Mayer,et al. Association of the v-crk oncogene product with phosphotyrosine-containing proteins and protein kinase activity. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[6] H. Varmus,et al. Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src , 1990, Molecular and cellular biology.
[7] M. Moran,et al. Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases , 1990, Nature.
[8] S. Smith,et al. Characterization of the breakpoint of a t(14;14)(q11.2;q32) from the leukemic cells of a patient with T-cell acute lymphoblastic leukemia. , 1990, Cancer genetics and cytogenetics.
[9] G. Martin,et al. Linker insertion-deletion mutagenesis of the v-src gene: isolation of host- and temperature-dependent mutants , 1989, Journal of virology.
[10] S. Klinken,et al. v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[11] T. Pawson,et al. Non-catalytic domains of cytoplasmic protein-tyrosine kinases: regulatory elements in signal transduction. , 1988, Oncogene.
[12] Irving S. Sigal,et al. Cloning of bovine GAP and its interaction with oncogenic ras p21 , 1988, Nature.
[13] T. Hunter,et al. The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. , 1988, Science.
[14] Y. Nishizuka,et al. The structure, expression, and properties of additional members of the protein kinase C family. , 1988, The Journal of biological chemistry.
[15] B. Mayer,et al. A novel viral oncogene with structural similarity to phospholipase C , 1988, Nature.
[16] R. Kriz,et al. Sequence similarity of phospholipase C with the non-catalytic region of src , 1988, Nature.
[17] J. Hartley,et al. Thymic lymphoma induction by the AKT8 murine retrovirus , 1988, The Journal of experimental medicine.
[18] C. Croce,et al. The AKT1 proto-oncogene maps to human chromosome 14, band q32. , 1988, Genomics.
[19] S. Staal. Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[20] H. Kawasaki,et al. Tissue-specific expression of three distinct types of rabbit protein kinase C , 1987, Nature.
[21] T Pawson,et al. A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps , 1986, Molecular and cellular biology.
[22] A. Ullrich,et al. Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways. , 1986, Science.
[23] J. Devereux,et al. A comprehensive set of sequence analysis programs for the VAX , 1984, Nucleic Acids Res..
[24] E. Reddy,et al. Gene product of v-fgr onc: hybrid protein containing a portion of actin and a tyrosine-specific protein kinase. , 1984, Science.
[25] D. Moscatelli,et al. Increased capillary endothelial cell protease activity in response to angiogenic stimuli in vitro. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[26] J. Hartley,et al. Isolation of transforming murine leukemia viruses from mice with a high incidence of spontaneous lymphoma. , 1977, Proceedings of the National Academy of Sciences of the United States of America.