Designing improved active peptides for therapeutic approaches against infectious diseases.
暂无分享,去创建一个
Axel Hollmann | N. Santos | M. T. Augusto | O. L. Franco | Mário R Felício | S. Gonçalves | Sónia Gonçalves | Nuno C Santos | Bárbara Gomes | A. Hollmann | Bárbara Gomes | Marcelo T Augusto | Octávio L Franco | Marcelo T. Augusto | Sónia Gonçalves
[1] Guangshun Wang,et al. Anti-Human Immunodeficiency Virus Type 1 Activities of Antimicrobial Peptides Derived from Human and Bovine Cathelicidins , 2008, Antimicrobial Agents and Chemotherapy.
[2] N. Santos,et al. Psd1 Effects on Candida albicans Planktonic Cells and Biofilms , 2017, Front. Cell. Infect. Microbiol..
[3] R. Nagaraj,et al. N-Terminal fatty acylation of peptides spanning the cationic C-terminal segment of bovine β-defensin-2 results in salt-resistant antibacterial activity. , 2015, Biophysical chemistry.
[4] M. Kumar,et al. HIPdb: A Database of Experimentally Validated HIV Inhibiting Peptides , 2013, PloS one.
[5] Philipp M. Cromm,et al. Protease-Resistant and Cell-Permeable Double-Stapled Peptides Targeting the Rab8a GTPase. , 2016, ACS chemical biology.
[6] Maarten Danial,et al. Site-specific PEGylation of HR2 peptides: effects of PEG conjugation position and chain length on HIV-1 membrane fusion inhibition and proteolytic degradation. , 2012, Bioconjugate chemistry.
[7] Michael Otto,et al. Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance , 2017, Nature Reviews Drug Discovery.
[8] A. Pini,et al. d-Amino acids incorporation in the frog skin-derived peptide esculentin-1a(1-21)NH2 is beneficial for its multiple functions , 2015, Amino Acids.
[9] R. Nagaraj,et al. Antimicrobial activity of human α‐defensin 6 analogs: insights into the physico‐chemical reasons behind weak bactericidal activity of HD6 in vitro , 2015, Journal of peptide science : an official publication of the European Peptide Society.
[10] M. Mckenna,et al. Antibiotic resistance: The last resort , 2013, Nature.
[11] D. Andreu,et al. Kinetic uptake profiles of cell penetrating peptides in lymphocytes and monocytes. , 2013, Biochimica et biophysica acta.
[12] D. Fuchs,et al. Importance of the N-Distal AP-2 Binding Element in Nef for Simian Immunodeficiency Virus Replication and Pathogenicity in Rhesus Macaques , 2006, Journal of Virology.
[13] I. Toth,et al. Immunostimulation by Synthetic Lipopeptide-Based Vaccine Candidates: Structure-Activity Relationships , 2013, Front. Immunol..
[14] Vladimir B. Bajic,et al. DAMPD: a manually curated antimicrobial peptide database , 2011, Nucleic Acids Res..
[15] R. Hancock,et al. Alternative mechanisms of action of cationic antimicrobial peptides on bacteria , 2007, Expert review of anti-infective therapy.
[16] K. Lee,et al. Effect of D-amino acid substitution on the stability, the secondary structure, and the activity of membrane-active peptide. , 1999, Biochemical pharmacology.
[17] R. Weissleder,et al. Arginine containing peptides as delivery vectors. , 2003, Advanced drug delivery reviews.
[18] Mie Kristensen,et al. Applications and Challenges for Use of Cell-Penetrating Peptides as Delivery Vectors for Peptide and Protein Cargos , 2016, International journal of molecular sciences.
[19] Suzana M. Ribeiro,et al. A polyalanine peptide derived from polar fish with anti-infectious activities , 2016, Scientific Reports.
[20] M. Saviano,et al. Determination of the secondary structure of peptides in the presence of Gram positive bacterium S. epidermidis cells , 2016 .
[21] Alan J. Waring,et al. Activities of LL-37, a Cathelin-Associated Antimicrobial Peptide of Human Neutrophils , 1998, Antimicrobial Agents and Chemotherapy.
[22] S. Joo. Cyclic Peptides as Therapeutic Agents and Biochemical Tools , 2012, Biomolecules & therapeutics.
[23] Ram Samudrala,et al. Structural Optimization and De Novo Design of Dengue Virus Entry Inhibitory Peptides , 2010, PLoS neglected tropical diseases.
[24] A. Gamarnik,et al. Dengue Virus Capsid Protein Usurps Lipid Droplets for Viral Particle Formation , 2009, PLoS pathogens.
[25] J. Levy,et al. Long-Term Specific Immune Responses Induced in Humans by a Human Immunodeficiency Virus Type 1 Lipopeptide Vaccine: Characterization of CD8+-T-Cell Epitopes Recognized , 2003, Journal of Virology.
[26] G. Płaza,et al. Antimicrobial, antiadhesive and antibiofilm potential of lipopeptides synthesised by Bacillus subtilis, on uropathogenic bacteria. , 2015, Acta biochimica Polonica.
[27] H. Vogel,et al. Tryptophan- and arginine-rich antimicrobial peptides: structures and mechanisms of action. , 2006, Biochimica et biophysica acta.
[28] O. Franco,et al. The next generation of antimicrobial peptides (AMPs) as molecular therapeutic tools for the treatment of diseases with social and economic impacts , 2016, Drug Discovery Today.
[29] John P. Moore,et al. Addition of a cholesterol group to an HIV-1 peptide fusion inhibitor dramatically increases its antiviral potency , 2009, Proceedings of the National Academy of Sciences.
[30] R. Nagaraj,et al. Antimicrobial activity of human α-defensin 5 and its linear analogs: N-terminal fatty acylation results in enhanced antimicrobial activity of the linear analogs , 2015, Peptides.
[31] Hongliang Lan,et al. Design and mechanism of action of a novel bacteria-selective antimicrobial peptide from the cell-penetrating peptide Pep-1. , 2006, Biochemical and biophysical research communications.
[32] H. Saito,et al. Conformation and dynamics of melittin bound to magnetically oriented lipid bilayers by solid-state (31)P and (13)C NMR spectroscopy. , 2000, Biophysical journal.
[33] Matthew T. Weinstock,et al. Protease‐resistant peptide design—empowering nature's fragile warriors against HIV , 2012, Biopolymers.
[34] J. Reichert,et al. Future directions for peptide therapeutics development. , 2013, Drug discovery today.
[35] N. Santos,et al. Defensins: antifungal lessons from eukaryotes , 2014, Front. Microbiol..
[36] O. Franco,et al. Structural and functional evaluation of the palindromic alanine-rich antimicrobial peptide Pa-MAP2. , 2016, Biochimica et biophysica acta.
[37] M. Porotto,et al. Fatal Measles Virus Infection Prevented by Brain-Penetrant Fusion Inhibitors , 2013, Journal of Virology.
[38] Florian Krammer,et al. An Amphibian Host Defense Peptide Is Virucidal for Human H1 Hemagglutinin‐Bearing Influenza Viruses , 2017, Immunity.
[39] P. Verhaert,et al. The emergence of peptides in the pharmaceutical business: From exploration to exploitation , 2014 .
[40] Olivier Taboureau,et al. Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus , 2005, Nature.
[41] D. Gantz,et al. Human Neutrophil Defensins Increase Neutrophil Uptake of Influenza A Virus and Bacteria and Modify Virus-Induced Respiratory Burst Responses , 2007, The Journal of Immunology.
[42] J. York,et al. Development of a candidate HLA A*0201 restricted peptide-based vaccine against human cytomegalovirus infection. , 1997, Blood.
[43] David Andreu,et al. New Potent Membrane-Targeting Antibacterial Peptides from Viral Capsid Proteins , 2017, Front. Microbiol..
[44] Pilju Youn,et al. A Myristoylated Cell-Penetrating Peptide Bearing a Transferrin Receptor-Targeting Sequence for Neuro-Targeted siRNA Delivery , 2014, Molecular pharmaceutics.
[45] Kai Hilpert,et al. High-throughput generation of small antibacterial peptides with improved activity , 2005, Nature Biotechnology.
[46] O. Teschke,et al. Effects of the antimicrobial peptide PGLa on live Escherichia coli. , 2003, Biochimica et biophysica acta.
[47] Gisbert Schneider,et al. Designing antimicrobial peptides: form follows function , 2012, Nature Reviews Drug Discovery.
[48] Manoj Kumar,et al. AVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses , 2013, Nucleic Acids Res..
[49] N. Santos,et al. Evaluation of the membrane lipid selectivity of the pea defensin Psd1. , 2012, Biochimica et biophysica acta.
[50] B. Murray,et al. Antibiotic-resistant bugs in the 21st century--a clinical super-challenge. , 2009, The New England journal of medicine.
[51] D. Nayak,et al. Lipid Raft Disruption by Cholesterol Depletion Enhances Influenza A Virus Budding from MDCK Cells , 2007, Journal of Virology.
[52] Yoonkyung Park,et al. The therapeutic applications of antimicrobial peptides (AMPs): a patent review , 2017, Journal of Microbiology.
[53] K. Hilpert,et al. Antimicrobial peptides: Cell Membrane and Microbial Surface Interactions. , 2016, Biochimica et biophysica acta.
[54] Maria Luisa Mangoni,et al. Effect of natural L- to D-amino acid conversion on the organization, membrane binding, and biological function of the antimicrobial peptides bombinins H. , 2006, Biochemistry.
[55] Derek Macmillan,et al. The Human Cathelicidin LL-37 Has Antiviral Activity against Respiratory Syncytial Virus , 2013, PloS one.
[56] J. Fox. Rare-disease drugs boosted by new Prescription Drug User Fee Act , 2012, Nature Biotechnology.
[57] C. Rousselle,et al. New advances in the transport of doxorubicin through the blood-brain barrier by a peptide vector-mediated strategy. , 2000, Molecular pharmacology.
[58] D. Andreu,et al. Uptake and cellular distribution of nucleolar targeting peptides (NrTPs) in different cell types , 2015, Biopolymers.
[59] Kumardeep Chaudhary,et al. Cell Penetrating Peptides , 2016 .
[60] Laura M. Palermo,et al. In Vivo Efficacy of Measles Virus Fusion Protein-Derived Peptides Is Modulated by the Properties of Self-Assembly and Membrane Residence , 2016, Journal of Virology.
[61] A. O. Carvalho,et al. PvD1 defensin, a plant antimicrobial peptide with inhibitory activity against Leishmania amazonensis , 2015, Bioscience reports.
[62] F. Chisari,et al. A virocidal amphipathic α-helical peptide that inhibits hepatitis C virus infection in vitro , 2008, Proceedings of the National Academy of Sciences.
[63] A. Pessi. Cholesterol‐conjugated peptide antivirals: a path to a rapid response to emerging viral diseases† , 2014, Journal of peptide science : an official publication of the European Peptide Society.
[64] R. Nagaraj,et al. Effect of Selectively Introducing Arginine and D-Amino Acids on the Antimicrobial Activity and Salt Sensitivity in Analogs of Human Beta-Defensins , 2013, PloS one.
[65] M. Cytryńska,et al. Defense peptides: recent developments , 2015, Biomolecular concepts.
[66] M. Zasloff. Antimicrobial peptides of multicellular organisms , 2002, Nature.
[67] G. Maccari,et al. BaAMPs: the database of biofilm-active antimicrobial peptides , 2015, Biofouling.
[68] R. Hancock,et al. Structure and Mechanism of Action of an Indolicidin Peptide Derivative with Improved Activity against Gram-positive Bacteria* , 2001, The Journal of Biological Chemistry.
[69] Josias H. Hamman,et al. Oral Delivery of Peptide Drugs , 2012, BioDrugs.
[70] Carol S. Lim,et al. Basics and recent advances in peptide and protein drug delivery. , 2013, Therapeutic delivery.
[71] R. Hancock,et al. Antibiofilm Peptides: Potential as Broad-Spectrum Agents , 2016, Journal of bacteriology.
[72] D. Rossi,et al. Cell-Penetrating Peptides: From Basic Research to Clinics. , 2017, Trends in pharmacological sciences.
[73] Miguel A R B Castanho,et al. Cell-penetrating peptides and antimicrobial peptides: how different are they? , 2006, The Biochemical journal.
[74] Abid Qureshi,et al. AVCpred: an integrated web server for prediction and design of antiviral compounds , 2016, Chemical biology & drug design.
[75] Kaiqun Li,et al. New influenza A Virus Entry Inhibitors Derived from the Viral Fusion Peptides , 2015, PloS one.
[76] M. Maharajan,et al. Zika Virus Infection: Current Concerns and Perspectives , 2016, Clinical Reviews in Allergy & Immunology.
[77] O. Franco,et al. Linear antimicrobial peptides with activity against herpes simplex virus 1 and Aichi virus , 2017, Biopolymers.
[78] J. Ferlay,et al. Recent trends in incidence of five common cancers in 26 European countries since 1988: Analysis of the European Cancer Observatory. , 2015, European journal of cancer.
[79] T. Schwartz,et al. High molecular weight PEGylation of human pancreatic polypeptide at position 22 improves stability and reduces food intake in mice , 2016, British journal of pharmacology.
[80] W. James,et al. HIV entry in macrophages is dependent on intact lipid rafts , 2009, Virology.
[81] G. Maisetta,et al. Antimicrobial peptides and their interaction with biofilms of medically relevant bacteria. , 2016, Biochimica et biophysica acta.
[82] Robert E W Hancock,et al. Rational Design of α-Helical Antimicrobial Peptides with Enhanced Activities and Specificity/Therapeutic Index* , 2005, Journal of Biological Chemistry.
[83] R. Wubbolts,et al. Fungicidal Mechanisms of Cathelicidins LL-37 and CATH-2 Revealed by Live-Cell Imaging , 2014, Antimicrobial Agents and Chemotherapy.
[84] R. Hammami,et al. BACTIBASE second release: a database and tool platform for bacteriocin characterization , 2010, BMC Microbiology.
[85] V. Smith,et al. Antimicrobial proteins: From old proteins, new tricks. , 2015, Molecular immunology.
[86] V. Uversky,et al. Antimicrobial potentials and structural disorder of human and animal defensins. , 2016, Cytokine & growth factor reviews.
[87] C. Lavoie,et al. Macrocyclic cell penetrating peptides: a study of structure-penetration properties. , 2015, Bioconjugate chemistry.
[88] Suzana M. Ribeiro,et al. Selective amino acid substitution reduces cytotoxicity of the antimicrobial peptide mastoparan. , 2016, Biochimica et biophysica acta.
[89] A. Schmidtchen,et al. Evaluation of Strategies for Improving Proteolytic Resistance of Antimicrobial Peptides by Using Variants of EFK17, an Internal Segment of LL-37 , 2008, Antimicrobial Agents and Chemotherapy.
[90] Ju Hyun Cho,et al. De novo generation of short antimicrobial peptides with enhanced stability and cell specificity. , 2014, The Journal of antimicrobial chemotherapy.
[91] S. Gellman,et al. Inhibition of Herpes Simplex Virus Type 1 Infection by Cationic β-Peptides , 2008, Antimicrobial Agents and Chemotherapy.
[92] E. Romanowski,et al. A Review of Antimicrobial Peptides and Their Therapeutic Potential as Anti-Infective Drugs , 2005, Current eye research.
[93] A. Rinaldi,et al. Antimicrobial Peptides , 2010, Methods in Molecular Biology.
[94] G. Bulaj,et al. Converting peptides into drug leads by lipidation. , 2012, Current medicinal chemistry.
[95] F. Albericio,et al. Short AntiMicrobial Peptides (SAMPs) as a class of extraordinary promising therapeutic agents , 2016, Journal of peptide science : an official publication of the European Peptide Society.
[96] R. Cortese,et al. A General Strategy to Endow Natural Fusion-protein-Derived Peptides with Potent Antiviral Activity , 2012, PloS one.
[97] I. Hamley. PEG-peptide conjugates. , 2014, Biomacromolecules.
[98] I. Martins,et al. The disordered N-terminal region of dengue virus capsid protein contains a lipid-droplet-binding motif. , 2012, The Biochemical journal.
[99] C. Mant,et al. Role of Peptide Hydrophobicity in the Mechanism of Action of α-Helical Antimicrobial Peptides , 2006, Antimicrobial Agents and Chemotherapy.
[100] A. Perkins,et al. Partial D-amino acid substitution: Improved enzymatic stability and preserved Ab recognition of a MUC2 epitope peptide. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[101] Graham Bell,et al. Experimental evolution of resistance to an antimicrobial peptide , 2006, Proceedings of the Royal Society B: Biological Sciences.
[102] M. X. Fernandes,et al. Escherichia coli Cell Surface Perturbation and Disruption Induced by Antimicrobial Peptides BP100 and pepR* , 2010, The Journal of Biological Chemistry.
[103] D. Craik,et al. The Future of Peptide‐based Drugs , 2013, Chemical biology & drug design.
[104] R. Cortese,et al. Dramatic Potentiation of the Antiviral Activity of HIV Antibodies by Cholesterol Conjugation* , 2014, The Journal of Biological Chemistry.
[105] M. Khrestchatisky,et al. Synthetic therapeutic peptides: science and market. , 2010, Drug discovery today.
[106] S. Futaki,et al. Arginine-rich Peptides , 2001, The Journal of Biological Chemistry.
[107] A. Beck‐Sickinger,et al. Peptides and peptide conjugates: therapeutics on the upward path. , 2012, Future medicinal chemistry.
[108] C. Tung,et al. Lipo-oligoarginines as effective delivery vectors to promote cellular uptake. , 2010, Molecular bioSystems.
[109] C. Ireland,et al. Anti-Parasitic Compounds from Streptomyces sp. Strains Isolated from Mediterranean Sponges , 2010, Marine drugs.
[110] George L. Drusano,et al. Antimicrobial pharmacodynamics: critical interactions of 'bug and drug' , 2004, Nature Reviews Microbiology.
[111] K. Sandvig,et al. Cell-Penetrating Peptides: Possibilities and Challenges for Drug Delivery in Vitro and in Vivo , 2015, Molecules.
[112] Miguel A. R. B. Castanho,et al. HIV-1 Fusion Inhibitor Peptides Enfuvirtide and T-1249 Interact with Erythrocyte and Lymphocyte Membranes , 2010, PloS one.
[113] B. Bechinger,et al. The structure, dynamics and orientation of antimicrobial peptides in membranes by multidimensional solid-state NMR spectroscopy. , 1999, Biochimica et biophysica acta.
[114] Li Tang,et al. Translocation of HIV TAT peptide and analogues induced by multiplexed membrane and cytoskeletal interactions , 2011, Proceedings of the National Academy of Sciences.
[115] Henrik Franzyk,et al. Cell-Penetrating Antimicrobial Peptides – Prospectives for Targeting Intracellular Infections , 2015, Pharmaceutical Research.
[116] B. Meibohm,et al. Pharmacokinetic aspects of biotechnology products. , 2004, Journal of pharmaceutical sciences.
[117] Michael V. Liga,et al. Antimicrobial nanomaterials for water disinfection and microbial control: potential applications and implications. , 2008, Water research.
[118] C. Heinis,et al. Strategies to prolong the plasma residence time of peptide drugs , 2010 .
[119] M. Mura,et al. The effect of amidation on the behaviour of antimicrobial peptides , 2016, European Biophysics Journal.
[120] Min Lu,et al. Inhibition of Nipah Virus Infection In Vivo: Targeting an Early Stage of Paramyxovirus Fusion Activation during Viral Entry , 2010, PLoS pathogens.
[121] N. Santos,et al. Role of amphipathicity and hydrophobicity in the balance between hemolysis and peptide-membrane interactions of three related antimicrobial peptides. , 2016, Colloids and surfaces. B, Biointerfaces.
[122] Soon-Cheol Hong,et al. Structural diversity of marine cyclic peptides and their molecular mechanisms for anticancer, antibacterial, antifungal, and other clinical applications , 2017, Peptides.
[123] C. B. Park,et al. Mechanism of action of the antimicrobial peptide buforin II: buforin II kills microorganisms by penetrating the cell membrane and inhibiting cellular functions. , 1998, Biochemical and biophysical research communications.
[124] Katsumi Matsuzaki,et al. Control of cell selectivity of antimicrobial peptides. , 2009, Biochimica et biophysica acta.
[125] S. Kim,et al. Cell penetrating peptide conjugated liposomes as transdermal delivery system of Polygonum aviculare L. extract. , 2015, International journal of pharmaceutics.
[126] Benhur Lee,et al. Broad-spectrum antivirals against viral fusion , 2015, Nature Reviews Microbiology.
[127] C. Heinis,et al. Principal references used in Chemical Society Publications as from January, 1960 , 1959 .
[128] B. Bishop,et al. Helical cationic antimicrobial peptide length and its impact on membrane disruption. , 2015, Biochimica et biophysica acta.
[129] Junguang Jiang,et al. Antimicrobial potency and selectivity of simplified symmetric-end peptides. , 2014, Biomaterials.
[130] N. Santos,et al. Lipid composition is a determinant for human defensin HNP1 selectivity. , 2012, Biopolymers.
[131] Kelly K. Lee,et al. Capturing a Fusion Intermediate of Influenza Hemagglutinin with a Cholesterol-conjugated Peptide, a New Antiviral Strategy for Influenza Virus* , 2011, The Journal of Biological Chemistry.
[132] N. Santos,et al. Lipid selectivity in novel antimicrobial peptides: Implication on antimicrobial and hemolytic activity. , 2017, Colloids and surfaces. B, Biointerfaces.
[133] N. Somia,et al. The Nature of the N-Terminal Amino Acid Residue of HIV-1 RNase H Is Critical for the Stability of Reverse Transcriptase in Viral Particles , 2014, Journal of Virology.
[134] K. Pärn,et al. The Antimicrobial and Antiviral Applications of Cell-Penetrating Peptides , 2015, Methods in molecular biology.
[135] M. N. Melo,et al. Antimicrobial peptides: linking partition, activity and high membrane-bound concentrations , 2009, Nature Reviews Microbiology.
[136] G. Rádis-Baptista,et al. Efficient cellular delivery of β-galactosidase mediated by NrTPs, a new family of cell-penetrating peptides. , 2011, Bioconjugate chemistry.
[137] Erin E. Gill,et al. The immunology of host defence peptides: beyond antimicrobial activity , 2016, Nature Reviews Immunology.
[138] H. Nishimasu,et al. Crystal structure of the plant receptor-like kinase TDR in complex with the TDIF peptide , 2016, Nature Communications.
[139] R. H. Baltz,et al. Daptomycin: from the mountain to the clinic, with essential help from Francis Tally, MD. , 2010, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[140] G. Rádis-Baptista,et al. Molecular characterization of the interaction of crotamine-derived nucleolar targeting peptides with lipid membranes. , 2012, Biochimica et biophysica acta.
[141] E. Disalvo,et al. Role of guanidinium group in the insertion of l-arginine in DMPE and DMPC lipid interphases. , 2010, Biochimica et biophysica acta.
[142] Youhua Li,et al. A general method for making peptide therapeutics resistant to serine protease degradation: application to dipeptidyl peptidase IV substrates. , 2013, Journal of medicinal chemistry.
[143] N. Santos,et al. Antiviral Lipopeptide-Cell Membrane Interaction Is Influenced by PEG Linker Length , 2017, Molecules.
[144] J. Söderlund,et al. The antimicrobial peptide LL-37 inhibits HIV-1 replication. , 2007, Current HIV research.
[145] N. Santos,et al. Lipophilicity is a key factor to increase the antiviral activity of HIV neutralizing antibodies. , 2016, Colloids and surfaces. B, Biointerfaces.
[146] Krishna Kumar,et al. Antimicrobial activity and protease stability of peptides containing fluorinated amino acids. , 2007, Journal of the American Chemical Society.
[147] Sakshi Sachdeva. Peptides as ‘Drugs’: The Journey so Far , 2016, International Journal of Peptide Research and Therapeutics.
[148] H. Sahl,et al. The Lantibiotic Mersacidin Inhibits Peptidoglycan Synthesis by Targeting Lipid II , 1998, Antimicrobial Agents and Chemotherapy.
[149] Karen G. N. Oshiro,et al. Antimicrobial Peptides from Fruits and Their Potential Use as Biotechnological Tools—A Review and Outlook , 2017, Front. Microbiol..
[150] Gianluca Pollastri,et al. CPPpred: prediction of cell penetrating peptides , 2013, Bioinform..
[151] S. Maurer-Stroh,et al. Understanding Dengue Virus Capsid Protein Interaction with Key Biological Targets , 2015, Scientific Reports.
[152] Mário R. Felício,et al. Peptides with Dual Antimicrobial and Anticancer Activities , 2017, Front. Chem..
[153] D. Andreu,et al. siRNA‐cell‐penetrating peptides complexes as a combinatorial therapy against chronic myeloid leukemia using BV173 cell line as model , 2017, Journal of controlled release : official journal of the Controlled Release Society.
[154] F. Albericio,et al. A comparative study of different presentation strategies for an HIV peptide immunogen. , 2004, Bioconjugate chemistry.
[155] Xiangdong Gao,et al. Genetic fusion of human FGF21 to a synthetic polypeptide improves pharmacokinetics and pharmacodynamics in a mouse model of obesity , 2016, British journal of pharmacology.
[156] V. Adam,et al. Perspective of Use of Antiviral Peptides against Influenza Virus , 2015, Viruses.
[157] Dong Ryul Lee,et al. Cell-penetrating peptide (CPP)-conjugated proteins is an efficient tool for manipulation of human mesenchymal stromal cells , 2014, Scientific Reports.
[158] Luis M. De Leon-Rodriguez,et al. Effect of antimicrobial peptides derived from human cathelicidin LL-37 on Entamoeba histolytica trophozoites. , 2013, Experimental parasitology.
[159] N. Fotouhi. 1. Peptide Therapeutics , 2015 .
[160] Andrew Gould,et al. Cyclotides, a novel ultrastable polypeptide scaffold for drug discovery. , 2011, Current pharmaceutical design.
[161] H. Riezman,et al. Distribution and functions of sterols and sphingolipids. , 2011, Cold Spring Harbor perspectives in biology.
[162] Marco M. Domingues,et al. Understanding dengue virus capsid protein disordered N-Terminus and pep14-23-based inhibition. , 2015, ACS chemical biology.
[163] N. Carballeira,et al. Biological and structural effects of the conjugation of an antimicrobial decapeptide with saturated, unsaturated, methoxylated and branched fatty acids , 2017, Journal of peptide science : an official publication of the European Peptide Society.
[164] Avinash Sonawane,et al. Antimicrobial peptides and proteins in mycobacterial therapy: current status and future prospects. , 2014, Tuberculosis.
[165] L. Gentilucci,et al. Chemical modifications designed to improve peptide stability: incorporation of non-natural amino acids, pseudo-peptide bonds, and cyclization. , 2010, Current pharmaceutical design.
[166] G. Molle,et al. Structure and mechanism of action of the antimicrobial peptide piscidin. , 2007, Biochemistry.
[167] Laura M. Palermo,et al. Broad spectrum antiviral activity for paramyxoviruses is modulated by biophysical properties of fusion inhibitory peptides , 2017, Scientific Reports.
[168] A. Barron,et al. Vipericidins: a novel family of cathelicidin-related peptides from the venom gland of South American pit vipers , 2014, Amino Acids.
[169] N. Santos,et al. Biophysical Properties and Antiviral Activities of Measles Fusion Protein Derived Peptide Conjugated with 25-Hydroxycholesterol , 2017, Molecules.
[170] C. Subbalakshmi,et al. Mechanism of antimicrobial action of indolicidin. , 1998, FEMS microbiology letters.
[171] Xia Li,et al. APD3: the antimicrobial peptide database as a tool for research and education , 2015, Nucleic Acids Res..
[172] J. Bode,et al. Rethinking amide bond synthesis , 2011, Nature.
[173] Suzana M. Ribeiro,et al. An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities , 2016, Scientific Reports.
[174] Jing He,et al. Mechanism Matters: A Taxonomy of Cell Penetrating Peptides. , 2015, Trends in biochemical sciences.
[175] John S. Brownstein,et al. The global distribution and burden of dengue , 2013, Nature.
[176] J. A. Vosloo,et al. Antifungal peptides: To be or not to be membrane active. , 2016, Biochimie.
[177] Y. Shai,et al. Ultrashort Peptide Bioconjugates Are Exclusively Antifungal Agents and Synergize with Cyclodextrin and Amphotericin B , 2011, Antimicrobial Agents and Chemotherapy.
[178] K. Chandran,et al. C-peptide inhibitors of Ebola virus glycoprotein-mediated cell entry: effects of conjugation to cholesterol and side chain-side chain crosslinking. , 2013, Bioorganic & medicinal chemistry letters.
[179] A. Schmidtchen,et al. Effect of hydrophobic modifications in antimicrobial peptides. , 2014, Advances in colloid and interface science.
[180] A. Nesburn,et al. A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challenge , 2009, Mucosal Immunology.
[181] R. Hancock,et al. D-enantiomeric peptides that eradicate wild-type and multidrug-resistant biofilms and protect against lethal Pseudomonas aeruginosa infections. , 2015, Chemistry & biology.
[182] Miguel A. R. B. Castanho,et al. Dengue Virus Capsid Protein Binding to Hepatic Lipid Droplets (LD) Is Potassium Ion Dependent and Is Mediated by LD Surface Proteins , 2011, Journal of Virology.
[183] H. Jenssen,et al. Anti‐HSV activity of lactoferrin and lactoferricin is dependent on the presence of heparan sulphate at the cell surface , 2004, Journal of medical virology.
[184] R. Hancock,et al. Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies , 2006, Nature Biotechnology.
[185] L. Otvos. Peptide-based drug design: here and now. , 2008, Methods in molecular biology.
[186] E. Dufourc. Sterols and membrane dynamics , 2008, Journal of chemical biology.
[187] Gajendra P. S. Raghava,et al. CPPsite 2.0: a repository of experimentally validated cell-penetrating peptides , 2015, Nucleic Acids Res..
[188] Marco M. Domingues,et al. Antimicrobial protein rBPI21-induced surface changes on Gram-negative and Gram-positive bacteria. , 2014, Nanomedicine : nanotechnology, biology, and medicine.
[189] A. Pini,et al. Esculentin-1a-Derived Peptides Promote Clearance of Pseudomonas aeruginosa Internalized in Bronchial Cells of Cystic Fibrosis Patients and Lung Cell Migration: Biochemical Properties and a Plausible Mode of Action , 2016, Antimicrobial Agents and Chemotherapy.
[190] Roger Beuerman,et al. Defensins knowledgebase: a manually curated database and information source focused on the defensins family of antimicrobial peptides , 2006, Nucleic Acids Res..
[191] Lee Whitmore,et al. The Peptaibol Database: a database for sequences and structures of naturally occurring peptaibols , 2004, Nucleic Acids Res..
[192] D. Craik,et al. Cyclization of the Antimicrobial Peptide Gomesin with Native Chemical Ligation: Influences on Stability and Bioactivity , 2013, Chembiochem : a European journal of chemical biology.
[193] Robert F. Garry,et al. Peptide entry inhibitors of enveloped viruses: The importance of interfacial hydrophobicity☆ , 2014, Biochimica et Biophysica Acta (BBA) - Biomembranes.
[194] T. Weiss,et al. Neutron off-plane scattering of aligned membranes. I. Method Of measurement. , 1998, Biophysical journal.
[195] M. Sugita,et al. Lipopeptides: a novel antigen repertoire presented by major histocompatibility complex class I molecules , 2016, Immunology.
[196] K. Brogden. Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? , 2005, Nature Reviews Microbiology.
[197] Matthew A. Cooper,et al. Contribution of Amphipathicity and Hydrophobicity to the Antimicrobial Activity and Cytotoxicity of β-Hairpin Peptides , 2016, ACS infectious diseases.
[198] N. Santos,et al. Conjugation of Cholesterol to HIV-1 Fusion Inhibitor C34 Increases Peptide-Membrane Interactions Potentiating Its Action , 2013, PloS one.
[199] N. Høiby,et al. Pseudomonas aeruginosa biofilms in cystic fibrosis. , 2010, Future microbiology.
[200] A. Schmidtchen,et al. End-Tagging of Ultra-Short Antimicrobial Peptides by W/F Stretches to Facilitate Bacterial Killing , 2009, PloS one.
[201] N. Santos,et al. Decoding distinct membrane interactions of HIV-1 fusion inhibitors using a combined atomic force and fluorescence microscopy approach. , 2013, Biochimica et biophysica acta.
[202] James J. Cunningham,et al. Physicochemical and Formulation Developability Assessment for Therapeutic Peptide Delivery—A Primer , 2014, The AAPS Journal.
[203] G. Schneider,et al. Designing antimicrobial peptides: form follows function , 2011, Nature Reviews Drug Discovery.
[204] K. Chou,et al. Prediction of Antimicrobial Peptides Based on Sequence Alignment and Feature Selection Methods , 2011, PloS one.
[205] V. D. de Lima,et al. Acute bacterial infection negatively impacts cancer specific survival of colorectal cancer patients. , 2014, World journal of gastroenterology.
[206] V. H. Maier,et al. Functional characterization of codCath, the mature cathelicidin antimicrobial peptide from Atlantic cod (Gadus morhua) , 2011, Peptides.
[207] N. Santos,et al. Improvement of HIV fusion inhibitor C34 efficacy by membrane anchoring and enhanced exposure. , 2014, The Journal of antimicrobial chemotherapy.
[208] I. Martins,et al. Dengue virus capsid protein interacts specifically with very low-density lipoproteins. , 2014, Nanomedicine : nanotechnology, biology, and medicine.
[209] Miguel A. R. B. Castanho,et al. Prediction of Antibacterial Activity from Physicochemical Properties of Antimicrobial Peptides , 2011, PloS one.
[210] K. Freeman,et al. Potent in vitro and in vivo antifungal activity of a small molecule host defense peptide mimic through a membrane-active mechanism , 2017, Scientific Reports.
[211] Rohana Yusof,et al. Identification of natural antimicrobial agents to treat dengue infection: In vitro analysis of latarcin peptide activity against dengue virus , 2014, BMC Microbiology.
[212] D. Raucher,et al. Cell-penetrating peptides: strategies for anticancer treatment. , 2015, Trends in molecular medicine.
[213] R. Nagaraj,et al. Engineering of a linear inactive analog of human β‐defensin 4 to generate peptides with potent antimicrobial activity , 2015, Journal of peptide science : an official publication of the European Peptide Society.
[214] O. Franco,et al. Structural and Functional Characterization of a Multifunctional Alanine-Rich Peptide Analogue from Pleuronectes americanus , 2012, PloS one.
[215] Rakesh Kumar,et al. dPABBs: A Novel in silico Approach for Predicting and Designing Anti-biofilm Peptides , 2016, Scientific Reports.
[216] W. Shafer,et al. Degradation of Human Antimicrobial Peptide LL-37 by Staphylococcus aureus-Derived Proteinases , 2004, Antimicrobial Agents and Chemotherapy.
[217] C. Chi,et al. Critical effect of peptide cyclization on the potency of peptide inhibitors against Dengue virus NS2B-NS3 protease. , 2012, Journal of medicinal chemistry.
[218] Mário R. Felício,et al. New frontiers for anti-biofilm drug development. , 2016, Pharmacology & therapeutics.
[219] Gajendra P. S. Raghava,et al. PEPlife: A Repository of the Half-life of Peptides , 2016, Scientific Reports.
[220] U. Pesonen,et al. Novel Delivery Systems for Improving the Clinical Use of Peptides , 2015, Pharmacological Reviews.
[221] Gajendra P. S. Raghava,et al. AntiBP2: improved version of antibacterial peptide prediction , 2010, BMC Bioinformatics.
[222] O L Franco,et al. Computational tools for exploring sequence databases as a resource for antimicrobial peptides. , 2017, Biotechnology advances.
[223] E. Ramsburg,et al. A mastoparan-derived peptide has broad-spectrum antiviral activity against enveloped viruses , 2013, Peptides.
[224] Faiza Hanif Waghu,et al. CAMPR3: a database on sequences, structures and signatures of antimicrobial peptides , 2015, Nucleic Acids Res..
[225] N. Santos,et al. Unravelling the molecular basis of the selectivity of the HIV-1 fusion inhibitor sifuvirtide towards phosphatidylcholine-rich rigid membranes. , 2010, Biochimica et biophysica acta.
[226] R. Hancock,et al. Sublethal Concentrations of Pleurocidin-Derived Antimicrobial Peptides Inhibit Macromolecular Synthesis in Escherichia coli , 2002, Antimicrobial Agents and Chemotherapy.
[227] M. Castanho,et al. Cell‐penetrating peptides: A tool for effective delivery in gene‐targeted therapies , 2014, IUBMB life.
[228] J. Ortín,et al. Mutations in the N-Terminal Region of Influenza Virus PB2 Protein Affect Virus RNA Replication but Not Transcription , 2003, Journal of Virology.
[229] Carino,et al. Oral insulin delivery. , 1999, Advanced drug delivery reviews.
[230] C. Fjell,et al. Screening and characterization of surface-tethered cationic peptides for antimicrobial activity. , 2009, Chemistry & biology.
[231] K. Hartshorn,et al. The Role of Antimicrobial Peptides in Influenza Virus Infection and Their Potential as Antiviral and Immunomodulatory Therapy , 2016, Pharmaceuticals.
[232] V. Sabesan,et al. Biofilm Disrupting Technology for Orthopedic Implants: What’s on the Horizon? , 2014, Front. Med..
[233] U. Holmskov,et al. Innate Defense against Influenza A Virus: Activity of Human Neutrophil Defensins and Interactions of Defensins with Surfactant Protein D1 , 2006, The Journal of Immunology.
[234] M. Tirrell,et al. Chain length dependence of antimicrobial peptide-fatty acid conjugate activity. , 2010, Journal of colloid and interface science.