Lactic acid bacteria bio-detoxified aflatoxins contaminated cereals, ameliorate toxicological effects and improve haemato-histological parameters in albino rats

Abstract This research is aimed at bio-detoxifying aflatoxins in artificially contaminated cereals using Lactic Acid Bacteria (LAB). LAB isolates showed inhibitory activity against toxigenic A. flavus. The in vitro assay revealed noticeable decrease in the quantity of the aflatoxin B1 (AFB1) and B2 (AFB2) in contaminated millet and sorghum treated with monoculture and co-culture LAB, respectively. The hematological parameters of the rats fed with contaminated diets treated with LAB were higher than the group fed with commercial diet. The toxic effect of aflatoxins on the livers of albino rats fed was ameliorated by the treatment of contaminated cereals with LAB.

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