Cytoskeletal Organization of the Human Inner Ear: III. Expression of Actin in the Cochlea

Cochleae from eight human fetuses at 14–18 weeks of gestation were analyzed for the presence of F-actin. In general, F-actin occurred rather uniformly distributed in all cell types. A particularly strong fluorescence for F-actin was found in the apical region of the greater epithelial ridge (where the inner hair cell is located) but not in the lesser epithelial ridge (where the outer hair cells are located). This difference in fluorescence can possibly be functionally related.

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