An overview of toxins and genes from the venom of the Asian scorpion Buthus martensi Karsch.

[1]  W. Hodgson,et al.  Pharmacology and biochemistry of spider venoms. , 2002, Toxicon : official journal of the International Society on Toxinology.

[2]  Louis W. Chang,et al.  Handbook of Neurotoxicology , 1995, Humana Press.

[3]  Shunyi Zhu,et al.  A naturally occurring non‐coding fusion transcript derived from scorpion venom gland: implication for the regulation of scorpion toxin gene expression , 2001, FEBS letters.

[4]  R. Norton,et al.  Characterization of unique amphipathic antimicrobial peptides from venom of the scorpion Pandinus imperator. , 2001, The Biochemical journal.

[5]  R. Stöcklin,et al.  Moving pieces in a proteomic puzzle: mass fingerprinting of toxic fractions from the venom of Tityus serrulatus (Scorpiones, Buthidae). , 2001, Rapid communications in mass spectrometry : RCM.

[6]  R. Guan,et al.  A depressant insect toxin with a novel analgesic effect from scorpion Buthus martensii Karsch. , 2001, Biochimica et biophysica acta.

[7]  I. Huys,et al.  OsK2, a new selective inhibitor of Kv1.2 potassium channels purified from the venom of the scorpion Orthochirus scrobiculosus. , 2001, Biochemical and biophysical research communications.

[8]  X. Zeng,et al.  Precursor nucleotide sequence and genomic organization of BmTXKS1, a new scorpion toxin-like peptide from Buthus martensii Karsch. , 2001, Toxicon : official journal of the International Society on Toxinology.

[9]  F. Peng,et al.  Molecular cloning and characterization of four scorpion K(+)-toxin-like peptides: a new subfamily of venom peptides (alpha-KTx14) and genomic analysis of a member. , 2001, Biochimie.

[10]  J. Chen,et al.  Cloning and characterization of cDNA sequences encoding two novel alpha-like-toxin precursors from the Chinese scorpion Buthus martensii Karsch. , 2001, Toxicon : official journal of the International Society on Toxinology.

[11]  Z. Chen,et al.  Isolation, purification and N-terminal sequencing of a bioactive peptide that alters action potentials from the venom of Buthus martensii Karsch. , 2001, Journal of natural toxins.

[12]  Y. Ji,et al.  Sodium current in NG108-15 cell inhibited by scorpion toxin BmKAS-1 and restored by its specific monoclonal antibodies. , 2001, Journal of natural toxins.

[13]  S. Kourrich,et al.  A new class of scorpion toxin binding sites related to an A‐type K+ channel: pharmacological characterization and localization in rat brain , 2001, FEBS letters.

[14]  R. Guan,et al.  A new insect neurotoxin AngP1 with analgesic effect from the scorpion Buthus martensii Karsch: purification and characterization. , 2001, The journal of peptide research : official journal of the American Peptide Society.

[15]  O. McManus,et al.  Potassium channels: from scorpion venoms to high-resolution structure. , 2001, Toxicon : official journal of the International Society on Toxinology.

[16]  I. Huys,et al.  Electrophysiological characterization of BmK M1, an α‐like toxin from Buthus martensi Karsch venom , 2001, FEBS Letters.

[17]  W. Liu,et al.  Molecular characterization of an anti-epilepsy peptide from the scorpion Buthus martensi Karsch. , 2001, European journal of biochemistry.

[18]  P. Gopalakrishnakone,et al.  Functional site of bukatoxin, an α‐type sodium channel neurotoxin from the Chinese scorpion (Buthus martensi Karsch) venom: probable role of the 52PDKVP56 loop , 2001, FEBS letters.

[19]  Yong-hua Ji,et al.  The inhibitory effects of BmK IT2, a scorpion neurotoxin on rat nociceptive flexion reflex and a possible mechanism for modulating voltage-gated Na+ channels , 2001, Neuropharmacology.

[20]  Xian-Chun Zeng,et al.  Precursor of a Novel Scorpion Venom Peptide (BmKn1) with no Disulfide Bridge from Buthus martensii Karsch , 2001, IUBMB life.

[21]  X. Mao,et al.  Molecular cloning and sequence analysis of cDNAs encoding a beta-toxin-like peptide and two MkTx I homologues from scorpion Buthus martensii Karsch. , 2001, Toxicon : official journal of the International Society on Toxinology.

[22]  Yong-hua Ji,et al.  Buthus martensi Karsch agonist of skeletal-muscle RyR-1, a scorpion active polypeptide: antinociceptive effect on rat peripheral nervous system and spinal cord, and inhibition of voltage-gated Na+ currents in dorsal root ganglion neurons , 2001, Neuroscience Letters.

[23]  C. Nichols,et al.  Ion channel localization : methods and protocols , 2001 .

[24]  M. Delepierre,et al.  High Affinity Scorpion Toxins for Studying Potassium and Sodium Channels , 2001 .

[25]  A. L. Goldin,et al.  Resurgence of sodium channel research. , 2001, Annual review of physiology.

[26]  L. Possani,et al.  Tc1, from Tityus cambridgei, is the first member of a new subfamily of scorpion toxin that blocks K+‐channels , 2000, FEBS letters.

[27]  Nine novel precursors of Buthus martensii scorpion α-toxin homologues. , 2000 .

[28]  R. Hahin,et al.  The isolation and purification of two peptides from the venom of Buthus martensii Karsch. , 2000, Toxicon : official journal of the International Society on Toxinology.

[29]  M. Mevissen,et al.  Structure, function and pharmacology of voltage-gated sodium channels , 2000, Naunyn-Schmiedeberg's Archives of Pharmacology.

[30]  J. Wu,et al.  Solution structure of BmP02, a new potassium channel blocker from the venom of the Chinese scorpion Buthus martensi Karsch. , 2000, Biochemistry.

[31]  Yong-hua Ji,et al.  The binding of BmK IT2, a depressant insect-selective scorpion toxin on mammal and insect sodium channels , 2000, Neuroscience Research.

[32]  M. Stankiewicz,et al.  Sequence and electrophysiological characterization of two insect‐selective excitatory toxins from the venom of the Chinese scorpion Buthus martensi , 2000, FEBS letters.

[33]  Christopher Miller An overview of the potassium channel family , 2000, Genome Biology.

[34]  G. Hu,et al.  Solution structure of BmP01 from the venom of scorpion Buthus martensii Karsch. , 2000, Biochemical and biophysical research communications.

[35]  Bing Chen,et al.  Antihyperalgesia effect of BmK IT2, a depressant insect-selective scorpion toxin in rat by peripheral administration , 2000, Brain Research Bulletin.

[36]  Y. Ji,et al.  Binding characteristics of BmK I, an alpha-like scorpion neurotoxic polypeptide, on cockroach nerve cord synaptosomes. , 2000, The journal of peptide research : official journal of the American Peptide Society.

[37]  W. Catterall,et al.  Molecular mechanisms of neurotoxin action on voltage-gated sodium channels. , 2000, Biochimie.

[38]  P. Escoubas,et al.  Structure and pharmacology of spider venom neurotoxins. , 2000, Biochimie.

[39]  M. Corona,et al.  Peptides and genes coding for scorpion toxins that affect ion-channels. , 2000, Biochimie.

[40]  Chen Li,et al.  Purification, cDNA cloning and function assessment of BmK abT, a unique component from the Old World scorpion species , 2000, FEBS letters.

[41]  A. Torres-Larios,et al.  Hadrurin, a new antimicrobial peptide from the venom of the scorpion Hadrurus aztecus. , 2000, European journal of biochemistry.

[42]  F. Peng,et al.  Cloning and characterization of a cDNA sequence encoding the precursor of a chlorotoxin-like peptide from the Chinese scorpion Buthus martensii Karsch. , 2000, Toxicon : official journal of the International Society on Toxinology.

[43]  P. Biggin,et al.  Potassium channel structure: domain by domain. , 2000, Current opinion in structural biology.

[44]  D. Jiang,et al.  Cloning and characterization of the cDNA sequences of two venom peptides from Chinese scorpion Buthus martensii Karsch (BmK). , 2000, Toxicon : official journal of the International Society on Toxinology.

[45]  J. J. Wu,et al.  The gene cloning and sequencing of Bm-12, a chlorotoxin-like peptide from the scorpion Buthus martensi Karsch. , 2000, Toxicon : official journal of the International Society on Toxinology.

[46]  R. Hahin,et al.  The isolation and characterization of a peptide that alters sodium channels from Buthus martensii Karsch. , 2000, Toxicon : official journal of the International Society on Toxinology.

[47]  W. Catterall,et al.  From Ionic Currents to Molecular Mechanisms The Structure and Function of Voltage-Gated Sodium Channels , 2000, Neuron.

[48]  J. J. Wu,et al.  Genomic organization of three novel toxins from the scorpion Buthus martensi Karsch that are active on potassium channels. , 2000, The Biochemical journal.

[49]  Wenxin Li,et al.  Cloning and Characterization of a Novel cDNA Sequence Encoding the Precursor of a Novel Venom Peptide (BmKbpp) Related to a Bradykinin‐Potentiating Peptide from Chinese Scorpion Buthus martensii Karsch , 2000, IUBMB life.

[50]  Gail Mandel,et al.  Nomenclature of Voltage-Gated Sodium Channels , 2000, Neuron.

[51]  B. Nilius,et al.  Chlorotoxin does not inhibit volume‐regulated, calcium‐activated and cyclic AMP‐activated chloride channels , 2000, British journal of pharmacology.

[52]  J. Desmet,et al.  A novel class of pore-forming peptides in the venom of parabuthus schlechteri Purcell (scorpions: buthidae) , 2000 .

[53]  E Blanc,et al.  Solution structure of BmKTX, a K+ blocker toxin from the Chinese scorpion Buthus Martensi , 2000, Proteins.

[54]  M. Wang,et al.  Structure of a new neurotoxin from the scorpion Buthus martensii Karsch at 1.76 A. , 2000, Acta crystallographica. Section D, Biological crystallography.

[55]  E. Mccleskey,et al.  Ion channels of nociception. , 2020, Annual review of physiology.

[56]  C. Chi,et al.  Expression and purification of the BmK M1 neurotoxin from the scorpion Buthus martensii Karsch. , 1999, Protein expression and purification.

[57]  G A Gutman,et al.  A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies. , 1999, Trends in pharmacological sciences.

[58]  Z. Zeng,et al.  Crystal structures of two alpha-like scorpion toxins: non-proline cis peptide bonds and implications for new binding site selectivity on the sodium channel. , 1999, Journal of molecular biology.

[59]  Hui Liu,et al.  Molecular cloning and sequencing of two ‘short chain’ and two ‘long chain’ K+ channel‐blocking peptides from the Chinese scorpion Buthus martensii Karsch , 1999, FEBS letters.

[60]  S. Dib-Hajj,et al.  Sodium channels, excitability of primary sensory neurons, and the molecular basis of pain , 1999, Muscle & nerve.

[61]  C. Chi,et al.  Molecular characterization of a new excitatory insect neurotoxin with an analgesic effect on mice from the scorpion Buthus martensi Karsch. , 1999, Toxicon : official journal of the International Society on Toxinology.

[62]  R. Eglen,et al.  Ions in the fire: recent ion-channel research and approaches to pain therapy. , 1999, Trends in pharmacological sciences.

[63]  S. Dib-Hajj,et al.  Sodium channels and pain. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[64]  Houming Wu,et al.  Purification, characterization and structural study of the neuro-peptides from scorpion Buthus martensi Karsch , 1999 .

[65]  C. Chi,et al.  Genomic organization of three neurotoxins active on small conductance Ca2+‐activated potassium channels from the scorpion Buthus martensi Karsch 1 , 1999, FEBS letters.

[66]  S. Boyce,et al.  The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways , 1999, Nature Neuroscience.

[67]  C. Chi,et al.  Gene cloning and sequencing of BmK AS and BmK AS-1, two novel neurotoxins from the scorpion Buthus martensi Karsch. , 1999, Toxicon : official journal of the International Society on Toxinology.

[68]  H. Rochat,et al.  Scorpion α‐like toxins, toxic to both mammals and insects, differentially interact with receptor site 3 on voltage‐gated sodium channels in mammals and insects , 1999, The European journal of neuroscience.

[69]  N. Yanaihara,et al.  Covalent structures of BmK AS and BmK AS-1, two novel bioactive polypeptides purified from Chinese scorpion Buthus martensi Karsch. , 1999, Toxicon : official journal of the International Society on Toxinology.

[70]  A. Jabs,et al.  Non-proline cis peptide bonds in proteins. , 1999, Journal of molecular biology.

[71]  C. Chi,et al.  The cDNA sequence of an excitatory insect selective neurotoxin from the scorpion Buthus martensi Karsch. , 1999, Toxicon : official journal of the International Society on Toxinology.

[72]  M. Wang,et al.  A series of bioactivity-variant neurotoxins from scorpion Buthus martensii Karsch: purification, crystallization and crystallographic analysis. , 1999, Acta crystallographica. Section D, Biological crystallography.

[73]  M J Sternberg,et al.  Conformational analysis of the first observed non-proline cis-peptide bond occurring within the complementarity determining region (CDR) of an antibody. , 1998, Journal of molecular biology.

[74]  M. Sternberg,et al.  Crystal structure at 1.95 A resolution of the breast tumour-specific antibody SM3 complexed with its peptide epitope reveals novel hypervariable loop recognition. , 1998, Journal of molecular biology.

[75]  A. Ménez,et al.  Functional architectures of animal toxins: a clue to drug design? , 1998, Toxicon : official journal of the International Society on Toxinology.

[76]  G. Kaczorowski,et al.  Scorpion toxins: tools for studying K+ channels. , 1998, Toxicon : official journal of the International Society on Toxinology.

[77]  V. Tugarinov,et al.  Sodium channel modifiers from scorpion venom: structure-activity relationship, mode of action and application. , 1998, Toxicon : official journal of the International Society on Toxinology.

[78]  E. Blanc,et al.  Solution structure of two new toxins from the venom of the Chinese scorpion Buthus martensi Karsch blockers of potassium channels. , 1998, Biochemistry.

[79]  M. Adams,et al.  Lycotoxins, Antimicrobial Peptides from Venom of the Wolf SpiderLycosa carolinensis * , 1998, The Journal of Biological Chemistry.

[80]  S. Zinn-Justin,et al.  Functional Anatomy of Scorpion Toxins Affecting Sodium Channels , 1998 .

[81]  R. Norton Structure and Function of Peptide and Protein Toxins from Marine Organisms , 1998 .

[82]  M. Stankiewicz,et al.  [Anti-insect scorpion toxins: historical account, activities and prospects]. , 1998, Comptes rendus des seances de la Societe de biologie et de ses filiales.

[83]  B. Robertson The real life of voltage-gated K+ channels: more than model behaviour. , 1997, Trends in pharmacological sciences.

[84]  J. Thompson,et al.  The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. , 1997, Nucleic acids research.

[85]  O. Pongs,et al.  Purification, characterization, and synthesis of three novel toxins from the Chinese scorpion Buthus martensi, which act on K+ channels. , 1997, Biochemistry.

[86]  C. Chi,et al.  The CDNA and genomic DNA sequences of a mammalian neurotoxin from the scorpion Buthus martensii Karsch. , 1997, Toxicon : official journal of the International Society on Toxinology.

[87]  D. Arad,et al.  Identification of Structural Elements of a Scorpion α-Neurotoxin Important for Receptor Site Recognition* , 1997, The Journal of Biological Chemistry.

[88]  N. Yanaihara,et al.  BmK AS, an active scorpion polypeptide, enhances [3H]noradrenaline release from rat hippocampal slices , 1997 .

[89]  C. Chi,et al.  Purification and sequence determination of a new neutral mammalian neurotoxin from the scorpion Buthus martensii Karsch. , 1997, Toxicon : official journal of the International Society on Toxinology.

[90]  P. Escoubas,et al.  Characterization of four toxins from Buthus martensi scorpion venom, which act on apamin-sensitive Ca2+-activated K+ channels. , 1997, European journal of biochemistry.

[91]  P. Gopalakrishnakone,et al.  Adrenergic and nitrergic responses of the rat isolated anococcygeus muscle to a new toxin (makatoxin I) from the venom of the scorpion Buthus martensi Karsch. , 1997, Journal of autonomic pharmacology.

[92]  P. Gopalakrishnakone,et al.  Makatoxin I, a Novel Toxin Isolated from the Venom of the Scorpion Buthus martensi Karsch, Exhibits Nitrergic Actions* , 1997, The Journal of Biological Chemistry.

[93]  H. Karoui,et al.  Purification, structure and activity of three insect toxins from Buthus occitanus tunetanus venom. , 1997, Toxicon : official journal of the International Society on Toxinology.

[94]  C. Granier,et al.  Biochemical and pharmacological characterization of a depressant insect toxin from the venom of the scorpion Buthacus arenicola. , 1997, European journal of biochemistry.

[95]  Y. Jan,et al.  Cloned potassium channels from eukaryotes and prokaryotes. , 1997, Annual review of neuroscience.

[96]  S. Terakawa,et al.  Two neurotoxins (BmK I and BmK II) from the venom of the scorpion Buthus martensi Karsch: purification, amino acid sequences and assessment of specific activity. , 1996, Toxicon : official journal of the International Society on Toxinology.

[97]  Z. Zeng,et al.  Crystal structure of an acidic neurotoxin from scorpion Buthus martensii Karsch at 1.85 A resolution. , 1996, Journal of molecular biology.

[98]  Z. Zeng,et al.  Crystal structure determination of an acidic neurotoxin (BmK M8) from scorpion Buthus martensii Karsch at 0.25 nm resolution. , 1996, Science in China. Series C, Life sciences.

[99]  E. Carlier,et al.  Scorpion Toxins Affecting Sodium Current Inactivation Bind to Distinct Homologous Receptor Sites on Rat Brain and Insect Sodium Channels (*) , 1996, Journal of Biological Chemistry.

[100]  L. Sivilotti,et al.  A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons , 1996, Nature.

[101]  H. Rochat,et al.  A bradykinin-potentiating peptide (peptide K12) isolated from the venom of Egyptian scorpion Buthus occitanus , 1995, Peptides.

[102]  W. Catterall Structure and function of voltage-gated ion channels. , 1995, Annual review of biochemistry.

[103]  S. Terakawa,et al.  Molecular characteristics of four new depressant insect neurotoxins purified from venom of Buthus martensi Karsch by HPLC. , 1994, Science in China. Series B, Chemistry, life sciences & earth sciences.

[104]  J. Fontecilla-Camps,et al.  Crystal structure of toxin II from the scorpion Androctonus australis Hector refined at 1.3 A resolution. , 1994, Journal of molecular biology.

[105]  S. Terakawa,et al.  Amino acid sequence of an excitatory insect-selective toxin (BmK IT) from venom of the scorpion Buthus martensi Karsch. , 1994, Science in China. Series B, Chemistry, life sciences & earth sciences.

[106]  M. Corona,et al.  The genomic region encoding toxin gamma from the scorpion Tityus serrulatus contains an intron , 1993, FEBS letters.

[107]  E. W. Alves,et al.  Peptide T, a novel bradykinin potentiator isolated from Tityus serrulatus scorpion venom. , 1993, Toxicon : official journal of the International Society on Toxinology.

[108]  G. Strichartz,et al.  Purification and characterization of chlorotoxin, a chloride channel ligand from the venom of the scorpion. , 1993, The American journal of physiology.

[109]  T. Nakajima,et al.  Brevinin-1 and -2, unique antimicrobial peptides from the skin of the frog, Rana brevipoda porsa. , 1992, Biochemical and biophysical research communications.

[110]  W. Catterall,et al.  Localization of receptor sites for insect-selective toxins on sodium channels by site-directed antibodies. , 1992, Biochemistry.

[111]  Ferreira La,et al.  Isolation of a bradykinin-potentiating factor from scorpion Tityus serrulatus venom. , 1992 .

[112]  V. Bindokas,et al.  Functional duality and structural uniqueness of depressant insect-selective neurotoxins. , 1991, Biochemistry.

[113]  C. Granier,et al.  An anti-insect toxin purified from the scorpion Androctonus australis Hector also acts on the alpha- and beta-sites of the mammalian sodium channel: sequence and circular dichroism study. , 1991, Biochemistry.

[114]  R. Norton,et al.  Structure and structure-function relationships of sea anemone proteins that interact with the sodium channel. , 1991, Toxicon : official journal of the International Society on Toxinology.

[115]  J E Wampler,et al.  Occurrence and role of cis peptide bonds in protein structures. , 1990, Journal of molecular biology.

[116]  P. Bougis,et al.  Precursors of Androctonus australis scorpion neurotoxins. Structures of precursors, processing outcomes, and expression of a functional recombinant toxin II. , 1989, The Journal of biological chemistry.

[117]  J. Fontecilla-Camps,et al.  The antigenic structure of a scorpion toxin. , 1989, Molecular immunology.

[118]  C. Granier,et al.  Structure/activity relationships of scorpion alpha-toxins. Multiple residues contribute to the interaction with receptors. , 1989, European journal of biochemistry.

[119]  Xiaoping Zhou,et al.  Purification and N-terminal partial sequence of anti-epilepsy peptide from venom of the scorpion Buthus martensii Karsch. , 1989, The Biochemical journal.

[120]  J. Fontecilla-Camps,et al.  Orthorhombic crystals and three-dimensional structure of the potent toxin II from the scorpion Androctonus australis Hector. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[121]  M. Zasloff,et al.  Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor , 1987 .

[122]  M. Lazdunski,et al.  Polypeptide Toxins as Tools to Study Voltage‐Sensitive Na+ Channels a , 1986, Annals of the New York Academy of Sciences.

[123]  C. Granier,et al.  Use of antibodies specific to defined regions of scorpion alpha-toxin to study its interaction with its receptor site on the sodium channel. , 1986, Biochemistry.

[124]  D. Kadouri,et al.  An excitatory and a depressant insect toxin from scorpion venom both affect sodium conductance and possess a common binding site. , 1985, Archives of biochemistry and biophysics.

[125]  B. Hille,et al.  Ionic channels of excitable membranes , 2001 .

[126]  R. Mains,et al.  Strategies for the biosynthesis of bioactive peptides , 1983, Trends in Neurosciences.

[127]  B. Martin,et al.  The primary structure of noxiustoxin: A K+ channel blocking peptide, purified from the venom of the scorpion Centruroides noxius Hoffmann , 1982 .

[128]  H. Rochat,et al.  Two types of scorpion receptor sites, one related to the activation, the other to the inactivation of the action potential sodium channel. , 1982, Toxicon : official journal of the International Society on Toxinology.

[129]  L. J. Cole,et al.  Antibacterial Action of Melittin, a Polypeptide from Bee Venom , 1968, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.