RDIVpSGP motif of ASPP2 binds to 14-3-3 and enhances ASPP2/k18/14-3-3 ternary complex formulation to promote BRAF/MEK/ERK signal inhibited cell proliferation in hepatocellular carcinoma

[1]  D. Cuevas-Ramos,et al.  Recent Understanding and Future Directions of Recurrent Corticotroph Tumors , 2021, Frontiers in Endocrinology.

[2]  A. Bishayee,et al.  Oncogenic and Tumor Suppressive Components of the Cell Cycle in Breast Cancer Progression and Prognosis , 2021, Pharmaceutics.

[3]  M. Fanarraga,et al.  Microtubule cytoskeleton-disrupting activity of MWCNTs: applications in cancer treatment , 2020, Journal of Nanobiotechnology.

[4]  T. Obsil,et al.  The 14-3-3 Proteins as Important Allosteric Regulators of Protein Kinases , 2020, International journal of molecular sciences.

[5]  S. Malek,et al.  Dimerization induced by C-terminal 14-3-3 binding is sufficient for BRAF kinase activation. , 2020, Biochemistry.

[6]  W. Kao Keratin expression by corneal and limbal stem cells during development. , 2020, Experimental eye research.

[7]  A. Meyer,et al.  Microbial enzymes catalyzing keratin degradation: Classification, structure, function , 2020, Biotechnology Advances.

[8]  Gregory F Weber,et al.  14-3-3 targets keratin intermediate filaments to mechanically sensitive cell–cell contacts , 2020, Molecular biology of the cell.

[9]  Dexi Chen,et al.  ASPP2 enhances chemotherapeutic sensitivity through the down-regulation of XIAP expression in a p53 independent manner in hepatocellular carcinoma. , 2019, Biochemical and biophysical research communications.

[10]  J. Ji,et al.  Deficiency of apoptosis-stimulating protein two of p53 promotes liver regeneration in mice by activating mammalian target of rapamycin , 2018, Scientific Reports.

[11]  Lin He,et al.  Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis , 2018, Cell Research.

[12]  M. Omary,et al.  Types I and II Keratin Intermediate Filaments. , 2018, Cold Spring Harbor perspectives in biology.

[13]  L. M. Stevers,et al.  Modulators of 14-3-3 Protein–Protein Interactions , 2017, Journal of medicinal chemistry.

[14]  B. Joe,et al.  Bioinformatic analysis reveals new determinants of antigenic 14-3-3 proteins and a novel antifungal strategy , 2017, PloS one.

[15]  S. Artandi,et al.  Control of Cellular Aging, Tissue Function, and Cancer by p53 Downstream of Telomeres. , 2017, Cold Spring Harbor perspectives in medicine.

[16]  Yong Zhou,et al.  ASPP2 Is a Novel Pan-Ras Nanocluster Scaffold , 2016, PloS one.

[17]  H. Fu,et al.  BRET: NanoLuc-Based Bioluminescence Resonance Energy Transfer Platform to Monitor Protein-Protein Interactions in Live Cells. , 2016, Methods in molecular biology.

[18]  Ning Li,et al.  Nuclear EGFR impairs ASPP2-p53 complex-induced apoptosis by inducing SOS1 expression in hepatocellular carcinoma , 2015, Oncotarget.

[19]  J. P. Fawcett,et al.  Synaptopodin-2 induces assembly of peripheral actin bundles and immature focal adhesions to promote lamellipodia formation and prostate cancer cell migration , 2015, Oncotarget.

[20]  J. Ge,et al.  [Construction of recombinant baculovirus vectors started by EF1alpha]. , 2014, Wei sheng wu xue bao = Acta microbiologica Sinica.

[21]  L. Cantley,et al.  Phosphorylation of BRAF by AMPK impairs BRAF-KSR1 association and cell proliferation. , 2013, Molecular cell.

[22]  M. Colombo,et al.  Ultrasound-guided intra-tumor injection of combined immunotherapy cures mice from orthotopic prostate cancer , 2013, Cancer Immunology, Immunotherapy.

[23]  M. Yaffe,et al.  Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response , 2013, Nature Reviews Molecular Cell Biology.

[24]  S. Llanos,et al.  ASPP1 and ASPP2 bind active RAS, potentiate RAS signalling and enhance p53 activity in cancer cells , 2013, Cell Death and Differentiation.

[25]  R. Sears,et al.  N terminus of ASPP2 binds to Ras and enhances Ras/Raf/MEK/ERK activation to promote oncogene-induced senescence , 2012, Proceedings of the National Academy of Sciences.

[26]  M. Buehler,et al.  Structure and mechanical properties of human trichocyte keratin intermediate filament protein. , 2012, Biomacromolecules.

[27]  Guangchuang Yu,et al.  clusterProfiler: an R package for comparing biological themes among gene clusters. , 2012, Omics : a journal of integrative biology.

[28]  K. Yoneda,et al.  Interaction of the profilaggrin N-terminal domain with loricrin in human cultured keratinocytes and epidermis. , 2012, The Journal of investigative dermatology.

[29]  M. Sakaguchi,et al.  Preclinical safety and efficacy of in situ REIC/Dkk-3 gene therapy for prostate cancer. , 2012, Acta medica Okayama.

[30]  S. Feinstein,et al.  Natural product derivative Bis(4-fluorobenzyl)trisulfide inhibits tumor growth by modification of β-tubulin at Cys 12 and suppression of microtubule dynamics , 2009, Molecular Cancer Therapeutics.

[31]  Sivaraj Sivaramakrishnan,et al.  Shear stress induced reorganization of the keratin intermediate filament network requires phosphorylation by protein kinase C zeta. , 2009, Molecular biology of the cell.

[32]  D. Felsher,et al.  Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage–response thresholds , 2009, Proceedings of the National Academy of Sciences.

[33]  H. Benyamini,et al.  The Structure and Interactions of the Proline-rich Domain of ASPP2* , 2008, Journal of Biological Chemistry.

[34]  N. Copeland,et al.  The tetraspanin protein peripherin-2 forms a complex with melanoregulin, a putative membrane fusion regulator. , 2007, Biochemistry.

[35]  William Arbuthnot Sir Lane,et al.  Comprehensive Proteomic Analysis of Interphase and Mitotic 14-3-3-binding Proteins* , 2004, Journal of Biological Chemistry.

[36]  T. Date,et al.  Hepatitis C virus core protein interacts with p53-binding protein, 53BP2/Bbp/ASPP2, and inhibits p53-mediated apoptosis. , 2004, Biochemical and biophysical research communications.

[37]  B. Hallberg Exoenzyme S binds its cofactor 14-3-3 through a non-phosphorylated motif. , 2001, Biochemical Society Transactions.

[38]  M. Omary,et al.  Disturbances in hepatic cell‐cycle regulation in mice with assembly‐deficient keratins 8/18 , 2001, Hepatology.

[39]  C. Bocca,et al.  Cytoskeleton-interacting activity of geiparvarin, diethylstilbestrol and conjugates. , 2001, Chemico-biological interactions.