Epidemiological characteristics of pandemic influenza H1N1 2009 and seasonal influenza infection

The median age of patients with pandemic influenza H1N1 2009 infection was reported as 20–25 years in initial case series from Europe and the United States. This has been lowered to 13 years in the US after testing of more patients, but this may reflect differential increased testing of school‐aged children as part of the pandemic response. The median age of patients with seasonal influenza A(H1N1) infection identified through sentinel surveillance in Western Australia and Victoria in 2007–2008 was 18 and 22 years, respectively. For pandemic influenza H1N1 2009 infection, the median age of the first 244 patients identified in WA was 22 years, and median age of the first 135 patients identified through sentinel surveillance in Victoria was 21 years. Other comparisons of the epidemiological features of pandemic and seasonal influenza are difficult because much less laboratory testing is done for seasonal than for pandemic influenza. While early surveillance data indicated co‐circulation of both pandemic and seasonal strains in WA and Victoria, more recent data from both states indicate an increasing predominance of pandemic influenza. If the evolving pandemic allows, we should take advantage of the increased testing being conducted for pandemic influenza to learn more about the real impact of laboratory‐confirmed seasonal influenza.

[1]  Collective Surveillance Group for New Influenz New influenza A(H1N1) virus infections in Spain, April-May 2009. , 2009, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

[2]  L. Finelli,et al.  Emergence of a novel swine-origin influenza A (H1N1) virus in humans. , 2009, The New England journal of medicine.

[3]  H. Kelly,et al.  H1N1 swine origin influenza infection in the United States and Europe in 2009 may be similar to H1N1 seasonal influenza infection in two Australian states in 2007 and 2008 , 2009, Influenza and other respiratory viruses.

[4]  C. Macintyre,et al.  Influenza-related hospitalisation and death in Australians aged 50 years and older , 2008, Vaccine.

[5]  Gerardo Chowell,et al.  Severe respiratory disease concurrent with the circulation of H1N1 influenza. , 2009, The New England journal of medicine.

[6]  I M Longini,et al.  Estimating household and community transmission parameters for influenza. , 1982, American journal of epidemiology.

[7]  Raul Rabadan,et al.  Differences in Patient Age Distribution between Influenza A Subtypes , 2009, PloS one.

[8]  A. Kumar,et al.  Emergence of a Novel Swine-Origin Influenza A (H1N1) Virus in Humans , 2010 .

[9]  G. Dinant,et al.  Mortality benefits of influenza vaccination in elderly people. , 2008, The Lancet. Infectious diseases.

[10]  Cecile Viboud,et al.  Mortality benefits of influenza vaccination in elderly people: an ongoing controversy. , 2007, The Lancet. Infectious diseases.

[11]  S. Senanayake Swine flu update: bringing home the bacon , 2009, Medical Journal of Australia.

[12]  L. Simonsen The global impact of influenza on morbidity and mortality. , 1999, Vaccine.

[13]  P. Scuffham,et al.  Influenza-related disease: the cost to the Australian healthcare system. , 2008, Vaccine.

[14]  J. Stockman Severe Respiratory Disease Concurrent with the Circulation of H1N1 Influenza , 2011 .

[15]  D. M. Fleming,et al.  The duration and magnitude of influenza epidemics: A study of surveillance data from sentinel general practices in England, Wales and the Netherlands , 1999, European Journal of Epidemiology.