X-ray spectral measurements for tungsten-anode from 20 to 49 kVp on a digital breast tomosynthesis system.

PURPOSE This paper presents new spectral measurements of a tungsten-target digital breast tomosynthesis (DBT) system, including spectra of 43-49 kVp. METHODS Raw x-ray spectra of 20-49 kVp were directly measured from the tube port of a Selenia Dimensions DBT system using a CdTe based spectrometer. Two configurations of collimation were employed: one with two tungsten pinholes of 25 μm and 200 μm diameters, and the other with a single pinhole of 25 μm diameter, for acquiring spectra from the focal spot and from the focal spot as well as its vicinity. Stripping correction was applied to the measured spectra to compensate distortions due to escape events. The measured spectra were compared with the existing mammographic spectra of the TASMIP model in terms of photon fluence per exposure, spectral components, and half-value layer (HVL). HVLs were calculated from the spectra with a numerical filtration of 0.7 mm aluminum and were compared against actual measurements on the DBT system using W/Al (target-filter) combination, without paddle in the beam. RESULTS The spectra from the double-pinhole configuration, in which the acceptance aperture pointed right at the focal spot, were harder than the single-pinhole spectra which include both primary and off-focus radiation. HVL calculated from the single-pinhole setup agreed with the measured HVL within 0.04 mm aluminum, while the HVL values from the double-pinhole setup were larger than the single-pinhole HVL by at most 0.1 mm aluminum. The spectra from single-pinhole setup agreed well with the TASMIP mammographic spectra, and are more relevant for clinical purpose. CONCLUSIONS The spectra data would be useful for future research on DBT system with tungsten targets.

[1]  C. Bacci,et al.  The use of cadmium telluride detectors for the qualitative analysis of diagnostic x-ray spectra. , 1984, Physics in medicine and biology.

[2]  J. Ravenel The Essential Physics of Medical Imaging, 2nd ed. , 2003 .

[3]  Satoshi Miyajima,et al.  CdZnTe detector in diagnostic x-ray spectroscopy. , 2002, Medical physics.

[4]  J. S. Laughlin,et al.  Absorbed radiation dose in mammography. , 1979, Radiology.

[5]  Ehsan Samei,et al.  Physical characterization of a prototype selenium-based full field digital mammography detector. , 2005, Medical physics.

[6]  G. Barnes,et al.  Spectral dependence of glandular tissue dose in screen-film mammography. , 1991, Radiology.

[7]  Sabee Molloi,et al.  Quantification of breast density with dual energy mammography: an experimental feasibility study. , 2010, Medical physics.

[8]  J. H. Hubbell,et al.  XCOM : Photon Cross Sections Database , 2005 .

[9]  C. D'Orsi,et al.  Computation of the glandular radiation dose in digital tomosynthesis of the breast. , 2006, Medical physics.

[10]  Andrzej A. Markowicz,et al.  Handbook of X-Ray Spectrometry , 2002 .

[11]  J. Boone Normalized glandular dose (DgN) coefficients for arbitrary X-ray spectra in mammography: computer-fit values of Monte Carlo derived data. , 2002, Medical physics.

[12]  J. H. Hubbell,et al.  Tables of X-Ray Mass Attenuation Coefficients and Mass Energy-Absorption Coefficients 1 keV to 20 MeV for Elements Z = 1 to 92 and 48 Additional Substances of Dosimetric Interest , 1995 .

[13]  T. R. Fewell,et al.  Molybdenum, rhodium, and tungsten anode spectral models using interpolating polynomials with application to mammography. , 1997, Medical physics.

[14]  M. Yaffe Mammographic density. Measurement of mammographic density , 2008, Breast Cancer Research.

[15]  Karla Kerlikowske,et al.  Compositional breast imaging using a dual-energy mammography protocol. , 2009, Medical physics.

[16]  CdZnTe detector in mammographic x-ray spectroscopy. , 2002, Physics in medicine and biology.

[17]  Ian Shaw,et al.  Design and performance of the prototype full field breast tomosynthesis system with selenium based flat panel detector , 2005, SPIE Medical Imaging.

[18]  Koji Maeda,et al.  Compton-scattering measurement of diagnostic x-ray spectrum using high-resolution Schottky CdTe detector. , 2005, Medical physics.

[19]  S. Kappadath,et al.  Quantitative evaluation of dual-energy digital mammography for calcification imaging. , 2004, Physics in medicine and biology.

[20]  J. Boone,et al.  An accurate method for computer-generating tungsten anode x-ray spectra from 30 to 140 kV. , 1997, Medical physics.

[21]  A. Karellas,et al.  Breast cancer imaging: a perspective for the next decade. , 2008, Medical physics.

[22]  Ehsan Samei,et al.  A technique optimization protocol and the potential for dose reduction in digital mammography. , 2010, Medical physics.

[23]  Frank Verhaegen,et al.  Monte Carlo simulation of a computed tomography x-ray tube , 2007, Physics in medicine and biology.

[24]  Ann-Katherine Carton,et al.  Optimization of a dual-energy contrast-enhanced technique for a photon-counting digital breast tomosynthesis system: II. An experimental validation. , 2010, Medical physics.

[25]  J. Kaufhold,et al.  A calibration approach to glandular tissue composition estimation in digital mammography. , 2002, Medical physics.

[26]  Ann-Katherine Carton,et al.  Optimization of a dual-energy contrast-enhanced technique for a photon-counting digital breast tomosynthesis system: I. A theoretical model. , 2010, Medical physics.

[27]  Thomas Mertelmeier,et al.  X-ray spectrum optimization of full-field digital mammography: simulation and phantom study. , 2006, Medical physics.

[28]  Ehsan Samei,et al.  Dual-energy contrast-enhanced breast tomosynthesis: optimization of beam quality for dose and image quality , 2011, Physics in medicine and biology.

[29]  Satoshi Miyajima,et al.  Thin CdTe detector in diagnostic x-ray spectroscopy. , 2003, Medical physics.

[30]  Loren Niklason,et al.  Advanced applications of digital mammography: tomosynthesis and contrast-enhanced digital mammography. , 2007, Seminars in roentgenology.

[31]  D. Dance,et al.  Estimation of mean glandular dose for breast tomosynthesis: factors for use with the UK, European and IAEA breast dosimetry protocols , 2011, Physics in medicine and biology.

[32]  Michael Sandborg,et al.  A search for optimal x-ray spectra in iodine contrast media mammography. , 2005, Physics in medicine and biology.

[33]  J. Pantazis,et al.  Characterization of CdTe Detectors for Quantitative X-ray Spectroscopy , 2009, IEEE Transactions on Nuclear Science.

[34]  G Belli,et al.  Physical characteristics of five clinical systems for digital mammography. , 2007, Medical physics.

[35]  Hong Liu,et al.  Error analysis in the measurement of x-ray photon fluence: an analysis on the uncertainty from energy calibration , 2009, BiOS.

[36]  S Suryanarayanan,et al.  Attenuation characteristics of fiberoptic plates for digital mammography and other X-ray imaging applications. , 2003, Journal of X-ray science and technology.

[37]  J. Boone,et al.  Glandular breast dose for monoenergetic and high-energy X-ray beams: Monte Carlo assessment. , 1999, Radiology.