INTRACELLULAR RECORDS FROM HIPPOCAMPAL PYRAMIDAL CELLS IN RABBIT DURING THETA RHYTHM ACTIVITY.

ONE OF THE MOST CONSPICUOUS FEATURES of the hippocampal EEGinthe rabbit is the existence of regular slow waves with a frequency of 3-8 cycles/ sec. These waves, the so-called “theta rhythm,” were discovered in 1938 by Jung and Kornmueller (17) and were studied in 1954 by Green and Arduini (10). The theta rhythm usually exists in unanesthetized animals and becomes prominent after various kinds of afferent stimulation or after stimulation of the midbrain reticular formation. The impulses generating the theta rhythm reach the hippocampus by way of the septum and the dorsal fornix (10, 22, 23). The theta rhythm is sometimes referred to as the hippocampal arousal pattern, because its appearance eous with that of the neocortical arousal waves (the is as a rule simultanlow-voltage and fast waves); in this descriptive sense the hippocampal EEG bears an inverse relationship to the neocortical EEG. As to the nature and origin of the theta rhythm, many investigations have been performed employing microelectrode technique

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