Acetylcholinesterase-amyloid-beta-peptide interaction: effect of Congo Red and the role of the Wnt pathway.
暂无分享,去创建一个
Tomás Pérez-Acle | Marcela Colombres | N. Inestrosa | T. Pérez-Acle | Nibaldo C Inestrosa | Alejandra Alvarez | A. Álvarez | Margarita C Dinamarca | Marcela Colombres | M. Dinamarca
[1] N. Inestrosa,et al. Acetylcholinesterase-Aβ Complexes Are More Toxic than Aβ Fibrils in Rat Hippocampus : Effect on Rat β-Amyloid Aggregation, Laminin Expression, Reactive Astrocytosis, and Neuronal Cell Loss , 2004 .
[2] Thomas Wisniewski,et al. The Interaction between Apolipoprotein E and Alzheimers Amyloid -Peptide Is Dependent on -Peptide Conformation (*) , 1996, The Journal of Biological Chemistry.
[3] Giancarlo V. De Ferrari and,et al. Wnt signaling function in Alzheimer’s disease , 2000, Brain Research Reviews.
[4] S. Brimijoin,et al. Acetylcholinesterase promotes beta-amyloid plaques in cerebral cortex , 2003, Neurobiology of Aging.
[5] H. Soreq,et al. Structural roles of acetylcholinesterase variants in biology and pathology. , 1999, European journal of biochemistry.
[6] P. Lansbury,et al. Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins. , 1997, Annual review of biochemistry.
[7] I Silman,et al. A structural motif of acetylcholinesterase that promotes amyloid beta-peptide fibril formation. , 2001, Biochemistry.
[8] N. Inestrosa,et al. Acetylcholinesterase–amyloid‐β‐peptide interaction and Wnt signaling involvement in Aβ neurotoxicity , 2000 .
[9] N. Inestrosa,et al. Acetylcholinesterase induces the expression of the β-amyloid precursor protein in glia and activates glial cells in culture , 2003, Neurobiology of Disease.
[10] N. Inestrosa,et al. Distribution and anchoring of molecular forms of acetylcholinesterase. , 1989, Trends in pharmacological sciences.
[11] B. Yankner,et al. Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[12] M. Findeis,et al. Modified-peptide inhibitors of amyloid beta-peptide polymerization. , 1999, Biochemistry.
[13] N. Inestrosa,et al. Laminin affects polymerization, depolymerization and neurotoxicity of Aβ peptide , 2002, Peptides.
[14] N. Inestrosa,et al. Acetylcholinesterase (AChE)--amyloid-beta-peptide complexes in Alzheimer's disease. the Wnt signaling pathway. , 2004, Current Alzheimer research.
[15] A. Goldman,et al. Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein , 1991, Science.
[16] R. Nusse,et al. Convergence of Wnt, ß-Catenin, and Cadherin Pathways , 2004, Science.
[17] Miguel Bronfman,et al. Signal transduction during amyloid-β-peptide neurotoxicity: role in Alzheimer disease , 2004, Brain Research Reviews.
[18] Ettore Novellino,et al. Specific targeting of acetylcholinesterase and butyrylcholinesterase recognition sites. Rational design of novel, selective, and highly potent cholinesterase inhibitors. , 2003, Journal of medicinal chemistry.
[19] Claudia Linker,et al. Acetylcholinesterase Accelerates Assembly of Amyloid-β-Peptides into Alzheimer's Fibrils: Possible Role of the Peripheral Site of the Enzyme , 1996, Neuron.
[20] N. Inestrosa,et al. Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by β-amyloid fibrils , 2003, Molecular Psychiatry.
[21] I. Tesseur,et al. No evidence for cholinergic problems in apolipoprotein E knockout and apolipoprotein E4 transgenic mice , 2000, Neuroscience.
[22] C. Geula,et al. Special properties of cholinesterases in the cerebral cortex of Alzheimer's disease , 1989, Brain Research.
[23] A. Cavalli,et al. 3-(4-[[Benzyl(methyl)amino]methyl]phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation: a dual function lead for Alzheimer's disease therapy. , 2003, Journal of medicinal chemistry.
[24] N. Inestrosa,et al. Peripheral binding site is involved in the neurotrophic activity of acetylcholinesterase. , 1999, Neuroreport.
[25] N. Inestrosa,et al. Acetylcholinesterase promotes the aggregation of amyloid-beta-peptide fragments by forming a complex with the growing fibrils. , 1997, Journal of molecular biology.
[26] N. Inestrosa,et al. Wnt-3a overcomes β-amyloid toxicity in rat hippocampal neurons , 2004 .
[27] B. P. Doctor,et al. Stable Complexes Involving Acetylcholinesterase and Amyloid-β Peptide Change the Biochemical Properties of the Enzyme and Increase the Neurotoxicity of Alzheimer’s Fibrils , 1998, The Journal of Neuroscience.