STAT1 Plays a Critical Role in the Regulation of Antimicrobial Effector Mechanisms, but Not in the Development of Th1-Type Responses during Toxoplasmosis1
暂无分享,去创建一个
[1] A. Satoskar,et al. Development of protective immunity against cutaneous leishmaniasis is dependent on STAT1‐mediated IFN signaling pathway , 2003, European journal of immunology.
[2] C. Wobus,et al. STAT1-Dependent Innate Immunity to a Norwalk-Like Virus , 2003, Science.
[3] Sami Al-Hajjar,et al. Impaired response to interferon-α/β and lethal viral disease in human STAT1 deficiency , 2003, Nature Genetics.
[4] A. Sher,et al. The Function of Gamma Interferon-Inducible GTP-Binding Protein IGTP in Host Resistance to Toxoplasma gondii Is Stat1 Dependent and Requires Expression in Both Hematopoietic and Nonhematopoietic Cellular Compartments , 2002, Infection and Immunity.
[5] C. Hunter,et al. Regulatory pathways involved in the infection-induced production of IFN-γ by NK cells , 2002 .
[6] R. Janssen,et al. Divergent Role for TNF-α in IFN-γ-Induced Killing of Toxoplasma gondii and Salmonella typhimurium Contributes to Selective Susceptibility of Patients with Partial IFN-γ Receptor 1 Deficiency1 , 2002, The Journal of Immunology.
[7] R. Salomon,et al. Critical Role for STAT4 Activation by Type 1 Interferons in the Interferon-γ Response to Viral Infection , 2002, Science.
[8] A. Sher,et al. T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[9] A. Sher,et al. Inactivation of Lrg-47 and Irg-47 Reveals a Family of Interferon γ–Inducible Genes with Essential, Pathogen-Specific Roles in Resistance to Infection , 2001, The Journal of experimental medicine.
[10] Steven M. Holland,et al. Impairment of Mycobacterial But Not Viral Immunity by a Germline Human STAT1 Mutation , 2001, Science.
[11] Chilakamarti V. Ramana,et al. Biologic consequences of Stat1-independent IFN signaling , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[12] Richard M. Ransohoff,et al. Stat1-independent regulation of gene expression in response to IFN-γ , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[13] U. Groß,et al. Toxoplasma gondii down‐regulates MHC class II gene expression and antigen presentation by murine macrophages via interference with nuclear translocation of STAT1α , 2001, European journal of immunology.
[14] Christine A. Biron,et al. Interferon α/β-mediated inhibition and promotion of interferon γ: STAT1 resolves a paradox , 2000, Nature Immunology.
[15] Laurie H Glimcher,et al. A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment , 2000, Cell.
[16] David E. Levy,et al. STAT1 Affects Lymphocyte Survival and Proliferation Partially Independent of Its Role Downstream of IFN-γ1 , 2000, The Journal of Immunology.
[17] A. Sher,et al. Pathogen-specific loss of host resistance in mice lacking the IFN-γ-inducible gene IGTP , 2000 .
[18] Mikhail Chernov,et al. Regulation of c‐myc expression by IFN‐γ through Stat1‐dependent and ‐independent pathways , 2000 .
[19] C. Hunter,et al. The NF-kappa B family member RelB is required for innate and adaptive immunity to Toxoplasma gondii. , 1999, Journal of immunology.
[20] K. Pfeffer,et al. Two families of GTPases dominate the complex cellular response to IFN-gamma. , 1998, Journal of immunology.
[21] H. Teh,et al. Specific antiviral activity demonstrated by TGTP, a member of a new family of interferon-induced GTPases. , 1998, Journal of immunology.
[22] E. Hudson,et al. The Inducibly Expressed GTPase Localizes to the Endoplasmic Reticulum, Independently of GTP Binding* , 1997, The Journal of Biological Chemistry.
[23] A. Sher,et al. Inducible Nitric Oxide Is Essential for Host Control of Persistent but Not Acute Infection with the Intracellular Pathogen Toxoplasma gondii , 1997, The Journal of experimental medicine.
[24] A. Sher,et al. In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection. , 1996, Journal of immunology.
[25] R. Schreiber,et al. Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway , 1996, Cell.
[26] R. Gazzinelli,et al. Effects of IL-12 on immune responses to microbial infections: a key mediator in regulating disease outcome. , 1995, Current opinion in immunology.
[27] C. Hunter,et al. Mitogen- and antigen-specific proliferation of T cells in murine toxoplasmosis is inhibited by reactive nitrogen intermediates , 1994, Infection and immunity.
[28] B. Sander,et al. Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen. Cytokine detection by immunoassay and intracellular immunostaining. , 1993, Journal of immunological methods.
[29] M. Lieser,et al. Oxidative priming of neutrophils by interferon‐y , 1993 .
[30] S. Russell,et al. A specific sequence of stimulation is required to induce synthesis of the antimicrobial molecule nitric oxide by mouse macrophages , 1992, Infection and immunity.
[31] J. Hibbs,et al. Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine. , 1990, Journal of immunology.
[32] H. Binz,et al. Modulation of Major Histocompatibility Complex (MHC) Expression by Interferons and Microbial Agents , 1988, Scandinavian journal of immunology.
[33] V. Brinkmann,et al. Different regulation of the L3T4-T cell subset by B cells in different mouse strains bearing the H-2k haplotype. , 1986, Journal of immunology.
[34] C. Nathan,et al. Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity , 1983, The Journal of experimental medicine.
[35] H. Erlich,et al. Western Blot analysis of the antigens of Toxoplasma gondii recognized by human IgM and IgG antibodies. , 1983, Journal of immunology.
[36] C. Nathan,et al. Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediates , 1979, The Journal of experimental medicine.
[37] Jianfei Yang,et al. T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells , 2002, Nature Immunology.
[38] U. Boehm,et al. Cellular responses to interferon-gamma. , 1997, Annual review of immunology.
[39] M. Lieser,et al. Oxidative priming of neutrophils by interferon-gamma. , 1993, Journal of leukocyte biology.