The Composition of Hemp Seed Oil and Its Potential as an Important Source of Nutrition

ABSTRACT The fatty acid and natural product content of hemp seed oil was analyzed by GC-MS and LC-MS. The presence of linoleic acid (LA) and a-linolenic acid (LNA) were confirmed in their previously reported ratio of 3:1 LA:LNA. The presence of β-caryophyllene (740 mg/L), myrcene (160 mg/L), β-sitosterol (100-148 g/L) and trace amounts of methyl salicylate was observed in the oil which had not been previously reported. Trace amounts of cannabidiol (CBD) were also detected. Bioassays were performed with the oil to determine its effectiveness as an antimicrobial agent. Some bioactivity was observed during the primary screening.

[1]  Fatty Acids,et al.  fatty acids , 2020, Catalysis from A to Z.

[2]  G. Wolf.  gamma-Tocopherol: an efficient protector of lipids against nitric oxide-initiated peroxidative damage. , 2009, Nutrition reviews.

[3]  A. Papas,et al.  Tocopherols and the etiology of colon cancer. , 1997, Journal of the National Cancer Institute.

[4]  V. Piironen,et al.  Antioxidant activity of minor amounts of γ-tocopherol in natural triacylglycerols , 1997 .

[5]  Y. Ikeshiro,et al.  Gastric cytoprotection of the non-steroidal anti-inflammatory sesquiterpene, beta-caryophyllene. , 1996, Planta medica.

[6]  Jean-Luc Deferne,et al.  Hemp seed oil: A source of valuable essential fatty acids , 1996 .

[7]  G. Spiteller.  Fats that Heal, Fats that Kill. Second Edition. 3. Auflage. Herausgegeben von Udo Erasmus. 456 pages. Alive Books, Burnaby Bc Canada. ISBN 0‐920470‐40‐8 (hard‐cover), ISBN 0‐920470‐38‐6 , 1996 .

[8]  P. Taylor,et al.  Effects of omega-3 fatty acid and vitamin E supplementation on erythrocyte membrane fluidity, tocopherols, insulin binding, and lipid composition in adult men , 1992 .

[9]  D. Jain,et al.  Occurrence of some antiviral sterols in Artemisia annua , 1991 .

[10]  T. Malini,et al.  Rat toxicity studies with β-sitosterol , 1990 .

[11]  S. Snider,et al.  Open label evaluation of cannabidiol in dystonic movement disorders. , 1986, The International journal of neuroscience.

[12]  S. Grundy,et al.  Optimizing the effect of plant sterols on cholesterol absorption in man. , 1982, The American journal of clinical nutrition.

[13]  S. A. Turkanis,et al.  The Cannabinoids as Potential Antiepileptics , 1981, Journal of clinical pharmacology.

[14]  W. Clarke.  Marijuana Botany: An Advanced Study: The Propagation and Breeding of Distinctive Cannabis , 1981 .

[15]  M. Elsohly,et al.  Constituents of Cannabis sativa L. XVII. A review of the natural constituents. , 1980, Journal of natural products.

[16]  S. Grundy,et al.  Plant sterols as cholesterol-lowering agents: clinical trials in patients with hypercholesterolemia and studies of sterol balance. , 1977, Atherosclerosis.

[17]  J. Visser,et al.  THE ESSENTIAL OIL OF CANNABIS SATIVA , 1975, Planta medica.

[18]  S. Sharma,et al.  Alkaloids and terpenoids of Ancistrocladus heyneanus, Sagittaria sagitifolia, Lyonia formosa and Hedychium spicatum☆ , 1975 .

[19]  S. A. Turkanis,et al.  The anticonvulsant activity of cannabidiol and cannabinol. , 1973, Life sciences.

[20]  A. Radosevic,et al.  Antibiotic Activity of Various Types of Cannabis Resin , 1962, Nature.