Time‐varying spectral analysis revealing differential effects of sevoflurane anaesthesia: non‐rhythmic‐to‐rhythmic ratio

Heart rate variability (HRV) may reflect various physiological dynamics. In particular, variation of R‐R peak interval (RRI) of electrocardiography appears regularly oscillatory in deeper levels of anaesthesia and less regular in lighter levels of anaesthesia. We proposed a new index, non‐rhythmic‐to‐rhythmic ratio (NRR), to quantify this feature and investigated its potential to estimate depth of anaesthesia.

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