The Mir-17∼92 Microrna Cluster Is a Global Regulator of Tumor Metabolism Recommended Citation
暂无分享,去创建一个
T. Duchaine | B. Samborska | A. Sergushichev | S. Sagan | M. Poffenberger | Ariel O. Donayo | Carine R. Lussier | E. Vincent | Ekaterina Loginicheva | Radia M. Johnson | Eric H. Ma | Said Izreig | Maxim N. Artyomov | Izreig | Said Samborska | Bozena Johnson | Radia M Sergushichev | Alexey Ma | Eric H Lussier | Carine Loginicheva | Ekaterina Donayo | Ariel O Poffenberger | Maya C Sagan | Selena M Vincent | Emma E Artyomov | Maxim N Duchaine | Thomas F | Jones | R. G | Russell G Jones
[1] W. Zong,et al. Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation. , 2015, Cell metabolism.
[2] Alexey Sergushichev,et al. Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth. , 2015, Molecular cell.
[3] B. Nielsen,et al. microRNA-17 Is the Most Up-Regulated Member of the miR-17-92 Cluster during Early Colon Cancer Evolution , 2015, PloS one.
[4] R. Gregory,et al. A Biogenesis Step Upstream of Microprocessor Controls miR-17∼92 Expression , 2015, Cell.
[5] M. V. Heiden,et al. Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells , 2015, Cell.
[6] D. Sabatini,et al. An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis , 2015, Cell.
[7] Charles Y. Lin,et al. Taming of the beast: shaping Myc-dependent amplification. , 2015, Trends in cell biology.
[8] Maxim N. Artyomov,et al. Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization. , 2015, Immunity.
[9] Lengchen Hou,et al. MicroRNA-17 promotes normal ovarian cancer cells to cancer stem cells development via suppression of the LKB1-p53-p21/WAF1 pathway , 2015, Tumor Biology.
[10] Takla Griss,et al. Differential effects of AMPK agonists on cell growth and metabolism , 2014, Oncogene.
[11] D. Dill,et al. MYC through miR-17-92 suppresses specific target genes to maintain survival, autonomous proliferation, and a neoplastic state. , 2014, Cancer cell.
[12] Steven J. M. Jones,et al. Comprehensive molecular profiling of lung adenocarcinoma , 2014, Nature.
[13] J. Ouyang,et al. MYC protein expression is associated with poor prognosis in diffuse large B cell lymphoma patients treated with RCHOP chemotherapy , 2014, Tumor Biology.
[14] Takla Griss,et al. Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1α , 2014, Proceedings of the National Academy of Sciences.
[15] B. Faubert,et al. PGC-1α supports glutamine metabolism in breast cancer , 2013, Cancer & metabolism.
[16] S. Gabriel,et al. Pan-cancer patterns of somatic copy-number alteration , 2013, Nature Genetics.
[17] G. Mills,et al. LKB1 is a central regulator of tumor initiation and pro-growth metabolism in ErbB2-mediated breast cancer , 2013, Cancer & metabolism.
[18] Z. Fei,et al. Integrative Analysis of miRNA and mRNA Profiles in Response to Ethylene in Rose Petals during Flower Opening , 2013, PloS one.
[19] Lin He,et al. mir‐17‐92: a polycistronic oncomir with pleiotropic functions , 2013, Immunological reviews.
[20] D. Tollervey,et al. Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding , 2013, Cell.
[21] A. McKenna,et al. Integrative eQTL-Based Analyses Reveal the Biology of Breast Cancer Risk Loci , 2013, Cell.
[22] Takla Griss,et al. AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo. , 2013, Cell metabolism.
[23] D. Green,et al. c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells , 2012, Cell.
[24] Charles Y. Lin,et al. Transcriptional Amplification in Tumor Cells with Elevated c-Myc , 2012, Cell.
[25] L. Staudt,et al. Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics , 2012, Nature.
[26] Steven J. M. Jones,et al. Comprehensive molecular characterization of human colon and rectal cancer , 2012, Nature.
[27] Benjamin E. Gross,et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. , 2012, Cancer discovery.
[28] Chi V Dang,et al. MYC on the Path to Cancer , 2012, Cell.
[29] M. Routbort,et al. Prognostic value of MYC rearrangement in cases of B‐cell lymphoma, unclassifiable, with features intermediate between diffuse large B‐cell lymphoma and Burkitt lymphoma , 2012, Cancer.
[30] A. Lane,et al. Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells. , 2012, Cell metabolism.
[31] P. Sethupathy,et al. Expression determinants of mammalian argonaute proteins in mediating gene silencing , 2011, Nucleic acids research.
[32] D. Green,et al. The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. , 2011, Immunity.
[33] M. V. Vander Heiden,et al. Aerobic glycolysis: meeting the metabolic requirements of cell proliferation. , 2011, Annual review of cell and developmental biology.
[34] Leah E. Mechanic,et al. Frequent homozygous deletion of the LKB1/STK11 gene in non-small cell lung cancer , 2011, Oncogene.
[35] J. M. Thomson,et al. miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. , 2011, Genes & development.
[36] T. Mäkelä,et al. Molecular mechanisms of tumor suppression by LKB1 , 2011, FEBS letters.
[37] N. Sonenberg,et al. Pervasive and cooperative deadenylation of 3'UTRs by embryonic microRNA families. , 2010, Molecular cell.
[38] Stuart H. Orkin,et al. A Myc Network Accounts for Similarities between Embryonic Stem and Cancer Cell Transcription Programs , 2010, Cell.
[39] K. Ohuchida,et al. MicroRNA miR-17-5p is overexpressed in pancreatic cancer, associated with a poor prognosis, and involved in cancer cell proliferation and invasion , 2010, Cancer biology & therapy.
[40] Lin He,et al. mir-17-92, a cluster of miRNAs in the midst of the cancer network. , 2010, The international journal of biochemistry & cell biology.
[41] S. Barrans,et al. Rearrangement of MYC is associated with poor prognosis in patients with diffuse large B-cell lymphoma treated in the era of rituximab. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[42] W. Filipowicz,et al. Regulation of mRNA translation and stability by microRNAs. , 2010, Annual review of biochemistry.
[43] Michael C. Ostrowski,et al. MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells. , 2010, Molecular cell.
[44] S. Lowe,et al. miR-19 is a key oncogenic component of mir-17-92. , 2009, Genes & development.
[45] Doron Betel,et al. Genetic dissection of the miR-17~92 cluster of microRNAs in Myc-induced B-cell lymphomas. , 2009, Genes & development.
[46] R. Gascoyne,et al. MYC gene rearrangements are associated with a poor prognosis in diffuse large B-cell lymphoma patients treated with R-CHOP chemotherapy. , 2009, Blood.
[47] R. Shaw,et al. The LKB1–AMPK pathway: metabolism and growth control in tumour suppression , 2009, Nature Reviews Cancer.
[48] Chin-Lee Wu,et al. mTOR and HIF-1α-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome , 2009, Proceedings of the National Academy of Sciences.
[49] Peter J. Woolf,et al. GAGE: generally applicable gene set enrichment for pathway analysis , 2009, BMC Bioinformatics.
[50] L. Cantley,et al. Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation , 2009, Science.
[51] Russell G. Jones,et al. Tumor suppressors and cell metabolism: a recipe for cancer growth. , 2009, Genes & development.
[52] D. Bartel. MicroRNAs: Target Recognition and Regulatory Functions , 2009, Cell.
[53] Anthony Mancuso,et al. Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction , 2008, Proceedings of the National Academy of Sciences.
[54] Ralph J Deberardinis,et al. Brick by brick: metabolism and tumor cell growth. , 2008, Current opinion in genetics & development.
[55] S. Landais,et al. Oncogenic potential of the miR-106-363 cluster and its implication in human T-cell leukemia. , 2007, Cancer research.
[56] E. Furth,et al. Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster , 2006, Nature Genetics.
[57] Y. Yatabe,et al. A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. , 2005, Cancer research.
[58] Daniel E Bauer,et al. ATP citrate lyase inhibition can suppress tumor cell growth. , 2005, Cancer cell.
[59] Kathryn A. O’Donnell,et al. c-Myc-regulated microRNAs modulate E2F1 expression , 2005, Nature.
[60] S. Lowe,et al. A microRNA polycistron as a potential human oncogene , 2005, Nature.
[61] R. DePinho,et al. The LKB1 tumor suppressor negatively regulates mTOR signaling. , 2004, Cancer cell.
[62] Hiroyuki Tagawa,et al. Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma. , 2004, Cancer research.
[63] Junying Yuan,et al. LKB1 — A master tumour suppressor of the small intestine and beyond , 2002, Nature Reviews Cancer.
[64] A. Ashworth,et al. The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinase. , 1999, Human molecular genetics.
[65] T. Rabbitts,et al. Translocation joins c-myc and immunoglobulin γ1 genes in a Burkitt lymphoma revealing a third exon in the c-myc oncogene , 1983, Nature.
[66] S. Weinberg,et al. Targeting mitochondria metabolism for cancer therapy. , 2015, Nature chemical biology.
[67] J. Stockman,et al. A Network Model of a Cooperative Genetic Landscape in Brain Tumors , 2011 .
[68] Tsung-Cheng Chang,et al. c-Myc suppression of miR-23 enhances mitochondrial glutaminase and glutamine metabolism , 2009, Nature.
[69] Tsung-Cheng Chang,et al. Widespread microRNA repression by Myc contributes to tumorigenesis , 2008, Nature Genetics.
[70] Min Wu,et al. Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells. , 2007, American journal of physiology. Cell physiology.