Simulation and probabilistic failure prediction of grafts for aortic aneurysm

Purpose – The use of stent‐grafts to canalize aortic blood flow for patients with aortic aneurysms is subject to serious failure mechanisms such as a leak between the stent‐graft and the aorta (Type I endoleak). The purpose of this paper is to describe a novel computational approach to understand the influence of relevant variables on the occurrence of stent‐graft failure and quantify the probability of failure for aneurysm patients.Design/methodology/approach – A parameterized fluid‐structure interaction finite element model of aortic aneurysm is built based on a multi‐material formulation available in LS‐DYNA. Probabilities of failure are assessed using an explicit construction of limit state functions with support vector machines (SVM) and uniform designs of experiments. The probabilistic approach is applied to two aneurysm geometries to provide a map of probabilities of failure for various design parameter values.Findings – Parametric studies conducted in the course of this research successfully ident...

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