A new procedure for amyloid β oligomers preparation enables the unambiguous testing of their effects on cytosolic and mitochondrial Ca2+ entry and cell death in primary neurons
暂无分享,去创建一个
[1] C. Villalobos,et al. Susceptibility to excitotoxicity in aged hippocampal cultures and neuroprotection by non‐steroidal anti‐inflammatory drugs: role of mitochondrial calcium , 2015, Journal of neurochemistry.
[2] P. Faller,et al. Role of metal ions in the self-assembly of the Alzheimer's amyloid-β peptide. , 2013, Inorganic chemistry.
[3] Yves F. Dufrêne,et al. Calcium Ions Promote Formation of Amyloid β-Peptide (1–40) Oligomers Causally Implicated in Neuronal Toxicity of Alzheimer's Disease , 2011, PloS one.
[4] M. Martín-Satué,et al. Amyloid β peptide oligomers directly activate NMDA receptors. , 2011, Cell calcium.
[5] E. Mandelkow,et al. Aβ Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines , 2010, The Journal of Neuroscience.
[6] M. Kawahara. Neurotoxicity of β-amyloid protein: oligomerization, channel formation, and calcium dyshomeostasis. , 2010, Current pharmaceutical design.
[7] O. Arancio,et al. Preparation of oligomeric beta-amyloid 1-42 and induction of synaptic plasticity impairment on hippocampal slices. , 2010, Journal of visualized experiments : JoVE.
[8] A. Gonzalo-Ruiz,et al. Soluble oligomeric forms of beta-amyloid (Aβ) peptide stimulate Aβ production via astrogliosis in the rat brain , 2010, Experimental Neurology.
[9] K. Jacobson,et al. Small molecule blockers of the Alzheimer Aβ calcium channel potently protect neurons from Aβ cytotoxicity , 2009, Proceedings of the National Academy of Sciences.
[10] I. Rodrı́guez-Crespo,et al. Mitochondrial Ca2+ Overload Underlies Aβ Oligomers Neurotoxicity Providing an Unexpected Mechanism of Neuroprotection by NSAIDs , 2008, PloS one.
[11] W. Klein,et al. Aβ Oligomers Induce Neuronal Oxidative Stress through an N-Methyl-D-aspartate Receptor-dependent Mechanism That Is Blocked by the Alzheimer Drug Memantine* , 2007, Journal of Biological Chemistry.
[12] J. García-Sancho,et al. Bioluminescence imaging of mitochondrial Ca2+ dynamics in soma and neurites of individual adult mouse sympathetic neurons , 2007, The Journal of physiology.
[13] D. Selkoe,et al. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide , 2007, Nature Reviews Molecular Cell Biology.
[14] J. Busciglio,et al. Different Conformations of Amyloid β Induce Neurotoxicity by Distinct Mechanisms in Human Cortical Neurons , 2006, The Journal of Neuroscience.
[15] Ian Parker,et al. Calcium Dysregulation and Membrane Disruption as a Ubiquitous Neurotoxic Mechanism of Soluble Amyloid Oligomers*♦ , 2005, Journal of Biological Chemistry.
[16] G. Krafft,et al. In Vitro Characterization of Conditions for Amyloid-β Peptide Oligomerization and Fibrillogenesis* , 2003, The Journal of Biological Chemistry.
[17] W. Klein. Aβ toxicity in Alzheimer’s disease: globular oligomers (ADDLs) as new vaccine and drug targets , 2002, Neurochemistry International.
[18] L. K. Baker,et al. Oligomeric and Fibrillar Species of Amyloid-β Peptides Differentially Affect Neuronal Viability* , 2002, The Journal of Biological Chemistry.
[19] T. Morgan,et al. Vaccination with soluble Aβ oligomers generates toxicity‐neutralizing antibodies , 2001, Journal of neurochemistry.
[20] P. Mantyh,et al. Aluminum, Iron, and Zinc Ions Promote Aggregation of Physiological Concentrations of β‐Amyloid Peptide , 1993, Journal of neurochemistry.
[21] D. Aldrich,et al. Metadata of the chapter that will be visualized online , 2014 .
[22] L. Núñez,et al. Study of neurotoxic intracellular calcium signalling triggered by amyloids. , 2012, Methods in molecular biology.
[23] J. García-Sancho,et al. Bioluminescence imaging of calcium oscillations inside intracellular organelles. , 2009, Methods in molecular biology.