Dihydroartemisinin inhibits the growth and invasion of gastric cancer cells by regulating cyclin D1-CDK4-Rb signaling.

[1]  Ming Chen,et al.  Triptolide inhibits PDGF-induced proliferation of ASMCs through G0/G1 cell cycle arrest and suppression of the AKT/NF-κB/cyclinD1 signaling pathway. , 2019, European journal of pharmacology.

[2]  A. Saneja,et al.  Hyaluronic acid - dihydroartemisinin conjugate: Synthesis, characterization and in vitro evaluation in lung cancer cells. , 2019, International journal of biological macromolecules.

[3]  Q. Ma,et al.  Effects of dihydroartemisinin on HSP70 expression in human prostate cancer PC‐3 cells , 2019, Andrologia.

[4]  Chen Li,et al.  Network pharmacology-based identification of the protective mechanisms of taraxasterol in experimental colitis. , 2019, International immunopharmacology.

[5]  N. Lu,et al.  Artemisinin derivatives inactivate cancer-associated fibroblasts through suppressing TGF-β signaling in breast cancer , 2018, Journal of Experimental & Clinical Cancer Research.

[6]  Haiyan Zhang,et al.  Dihydroartemisinin induces apoptosis and inhibits proliferation, migration, and invasion in epithelial ovarian cancer via inhibition of the hedgehog signaling pathway , 2018, Cancer medicine.

[7]  A. Jemal,et al.  Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries , 2018, CA: a cancer journal for clinicians.

[8]  Hui Liu,et al.  LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway , 2017, Journal of experimental & clinical cancer research : CR.

[9]  Nelson E. Brown,et al.  Palbociclib‐induced autophagy and senescence in gastric cancer cells , 2017, Experimental cell research.

[10]  K. Tang,et al.  Transcriptome Analysis of Genes Associated with the Artemisinin Biosynthesis by Jasmonic Acid Treatment under the Light in Artemisia annua , 2017, Front. Plant Sci..

[11]  Lijun Shui,et al.  Cigarette smoke extract alters the cell cycle via the phospholipid transfer protein/transforming growth factor-β1/CyclinD1/CDK4 pathway. , 2016, European journal of pharmacology.

[12]  M. Shah Update on metastatic gastric and esophageal cancers. , 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[13]  A. Di Leo,et al.  Cyclin-dependent kinase 4/6 inhibitors in breast cancer therapy , 2014, Current opinion in oncology.

[14]  S. Eckhardt,et al.  Targeting nuclear kinases in cancer: development of cell cycle kinase inhibitors. , 2014, Pharmacology & therapeutics.

[15]  Andrew C. Wood,et al.  Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma , 2013, Clinical Cancer Research.

[16]  F. Dick,et al.  The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle , 2012, Cell Division.

[17]  Robert L. Sutherland,et al.  Cyclin D as a therapeutic target in cancer , 2011, Nature Reviews Cancer.

[18]  D. Hanahan,et al.  Hallmarks of Cancer: The Next Generation , 2011, Cell.

[19]  Jin-jian Lu,et al.  The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells , 2011, Investigational New Drugs.

[20]  M. Barbacid,et al.  Cell cycle, CDKs and cancer: a changing paradigm , 2009, Nature Reviews Cancer.

[21]  Jan Koster,et al.  Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma. , 2008, Cancer research.

[22]  J. Harbour,et al.  Cdk Phosphorylation Triggers Sequential Intramolecular Interactions that Progressively Block Rb Functions as Cells Move through G1 , 1999, Cell.