IRF3 inhibits IFN‐γ‐mediated restriction of intracellular pathogens in macrophages independently of IFNAR
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R. Raychowdhury | N. Hacohen | Schraga Schwartz | A. Schneider | J. Coers | K. Maciag | Maxwell R Mumbach | Karen Smith | Alexis M. Schneider
[1] Jordan V. Price,et al. IRG1 and Inducible Nitric Oxide Synthase Act Redundantly with Other Interferon-Gamma-Induced Factors To Restrict Intracellular Replication of Legionella pneumophila , 2019, mBio.
[2] Arthur S Slutsky,et al. Pulmonary phagocyte-derived NPY controls the pathology of severe influenza virus infection , 2018, Nature Microbiology.
[3] S. Gordon,et al. Tissue macrophages: heterogeneity and functions , 2017, BMC Biology.
[4] H. Tilg,et al. Lipocalin-2: A Master Mediator of Intestinal and Metabolic Inflammation , 2017, Trends in Endocrinology & Metabolism.
[5] G. Sen,et al. RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway , 2016, Protein & Cell.
[6] D. Zamboni,et al. Caspase-1 but Not Caspase-11 Is Required for NLRC4-Mediated Pyroptosis and Restriction of Infection by Flagellated Legionella Species in Mouse Macrophages and In Vivo , 2015, The Journal of Immunology.
[7] S. Barik,et al. Induction of Interferon-Stimulated Genes by IRF3 Promotes Replication of Toxoplasma gondii , 2015, PLoS pathogens.
[8] C. Bogdan. Nitric oxide synthase in innate and adaptive immunity: an update. , 2015, Trends in immunology.
[9] U. Schaible,et al. Macrophage defense mechanisms against intracellular bacteria , 2015, Immunological reviews.
[10] J. Casanova,et al. Mendelian susceptibility to mycobacterial disease: genetic, immunological, and clinical features of inborn errors of IFN-γ immunity. , 2014, Seminars in immunology.
[11] Anna R Martirosyan,et al. Type I IFN Induces IL-10 Production in an IL-27–Independent Manner and Blocks Responsiveness to IFN-γ for Production of IL-12 and Bacterial Killing in Mycobacterium tuberculosis–Infected Macrophages , 2014, The Journal of Immunology.
[12] G. Weiss,et al. Iron at the interface of immunity and infection , 2014, Front. Pharmacol..
[13] Masahiro Yamamoto,et al. Guanylate binding proteins promote caspase-11–dependent pyroptosis in response to cytoplasmic LPS , 2014, Proceedings of the National Academy of Sciences.
[14] Ke Chen,et al. Interferon regulatory factor 3 constrains IKKβ/NF‐κB signaling to alleviate hepatic steatosis and insulin resistance , 2014, Hepatology.
[15] M. Jefferson,et al. The Pestivirus N Terminal Protease Npro Redistributes to Mitochondria and Peroxisomes Suggesting New Sites for Regulation of IRF3 by Npro , 2014, PloS one.
[16] Sunny Shin,et al. Inflammasome-mediated cell death in response to bacterial pathogens that access the host cell cytosol: lessons from legionella pneumophila , 2013, Front. Cell. Infect. Microbiol..
[17] Schraga Schwartz,et al. High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis , 2013, Cell.
[18] Eugenia G. Giannopoulou,et al. Synergistic activation of inflammatory cytokine genes by interferon-γ-induced chromatin remodeling and toll-like receptor signaling. , 2013, Immunity.
[19] O. Leo,et al. Interferon regulatory factor 3 controls interleukin-17 expression in CD8 T lymphocytes , 2013, Proceedings of the National Academy of Sciences.
[20] M. Muckenthaler,et al. Nitric oxide–mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection , 2013, The Journal of experimental medicine.
[21] T. Graeber,et al. Type I Interferon Suppresses Type II Interferon–Triggered Human Anti-Mycobacterial Responses , 2013, Science.
[22] L. Lenz,et al. Differential effects of type I and II interferons on myeloid cells and resistance to intracellular bacterial infections , 2013, Immunologic research.
[23] J. Alcorn,et al. Lipocalin 2 Regulates Inflammation during Pulmonary Mycobacterial Infections , 2012, PloS one.
[24] M. Starnbach,et al. IFNγ Inhibits the Cytosolic Replication of Shigella flexneri via the Cytoplasmic RNA Sensor RIG-I , 2012, PLoS pathogens.
[25] F. Shao,et al. Preventing bacterial DNA release and absent in melanoma 2 inflammasome activation by a Legionella effector functioning in membrane trafficking , 2012, Proceedings of the National Academy of Sciences.
[26] R. Myers,et al. IκB kinase ε (IKKε) regulates the balance between type I and type II interferon responses , 2011, Proceedings of the National Academy of Sciences.
[27] Sunny Shin,et al. Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice , 2011, Cellular microbiology.
[28] Colin N. Dewey,et al. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome , 2011, BMC Bioinformatics.
[29] Kevin A. Robertson,et al. Reversible Inhibition of Murine Cytomegalovirus Replication by Gamma Interferon (IFN-γ) in Primary Macrophages Involves a Primed Type I IFN-Signaling Subnetwork for Full Establishment of an Immediate-Early Antiviral State , 2011, Journal of Virology.
[30] A. Da'dara,et al. Type I Interferons Increase Host Susceptibility to Trypanosoma cruzi Infection , 2011, Infection and Immunity.
[31] D. Zamboni,et al. Innate Immunity to Legionella Pneumophila , 2011, Front. Microbio..
[32] D. Levy,et al. Functional Crosstalk between Type I and II Interferon through the Regulated Expression of STAT1 , 2010, PLoS biology.
[33] M. Robinson,et al. A scaling normalization method for differential expression analysis of RNA-seq data , 2010, Genome Biology.
[34] L. Lenz,et al. The Journal of Experimental Medicine CORRESPONDENCE , 2005 .
[35] S. Taki. Faculty Opinions recommendation of Induction of IFN-alphabeta enables Listeria monocytogenes to suppress macrophage activation by IFN-gamma. , 2010 .
[36] H. Nahrevanian. Involvement of nitric oxide and its up/down stream molecules in the immunity against parasitic infections. , 2009, The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases.
[37] C. Hong,et al. Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice. , 2009, The Journal of clinical investigation.
[38] R. Vance,et al. Identification of Host Cytosolic Sensors and Bacterial Factors Regulating the Type I Interferon Response to Legionella pneumophila , 2009, PLoS pathogens.
[39] Zhijian J. Chen,et al. RNA Polymerase III Detects Cytosolic DNA and Induces Type I Interferons through the RIG-I Pathway , 2009, Cell.
[40] T. Taniguchi,et al. Cell type-dependent proapoptotic role of Bcl2L12 revealed by a mutation concomitant with the disruption of the juxtaposed Irf3 gene , 2009, Proceedings of the National Academy of Sciences.
[41] S. Baratchi,et al. Recent advances on the roles of NO in cancer and chronic inflammatory disorders. , 2009, Current medicinal chemistry.
[42] H. Changotra,et al. Type I and Type II Interferons Inhibit the Translation of Murine Norovirus Proteins , 2009, Journal of Virology.
[43] R. Flavell,et al. Multiple MyD88‐dependent responses contribute to pulmonary clearance of Legionella pneumophila , 2009, Cellular microbiology.
[44] Xiaoyu Hu,et al. Regulation of interferon and Toll‐like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms , 2008, Immunological reviews.
[45] David E Levy,et al. IFNgamma signaling-does it mean JAK-STAT? , 2008, Cytokine & growth factor reviews.
[46] C. Schiffer,et al. Contribution of Ser386 and Ser396 to activation of interferon regulatory factor 3. , 2008, Journal of molecular biology.
[47] Roger E Bumgarner,et al. Independent and Cooperative Antiviral Actions of Beta Interferon and Gamma Interferon against Herpes Simplex Virus Replication in Primary Human Fibroblasts , 2007, Journal of Virology.
[48] Hiroyuki Oshiumi,et al. Spatiotemporal Mobilization of Toll/IL-1 Receptor Domain-Containing Adaptor Molecule-1 in Response to dsRNA1 , 2007, The Journal of Immunology.
[49] W. Dietrich,et al. Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/Ipaf signalling pathways , 2007, Cellular microbiology.
[50] K. Heuner,et al. Interferon‐Gamma Reverses the Evasion of Birc1e/Naip5 Gene Mediated Murine Macrophage Immunity by Legionella pneumophila Mutant Lacking Flagellin , 2007, Microbiology and immunology.
[51] Ryan M. O’Connell,et al. A role for IRF3-dependent RXRα repression in hepatotoxicity associated with viral infections , 2006, The Journal of experimental medicine.
[52] Kate Schroder,et al. Signal integration between IFNgamma and TLR signalling pathways in macrophages. , 2006, Immunobiology.
[53] Jiang-xia Liu,et al. Hyper-activated IRF-1 and STAT1 contribute to enhanced Interferon stimulated gene (ISG) expression by Interferon α and γ co-treatment in human hepatoma cells , 2006, Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression.
[54] Takuma Tsukahara,et al. Differential gene induction by type I and type II interferons and their combination. , 2006, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
[55] M. Swanson,et al. Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection , 2006, The Journal of experimental medicine.
[56] Anne E Carpenter,et al. A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen , 2006, Cell.
[57] W. Dietrich,et al. Flagellin-Deficient Legionella Mutants Evade Caspase-1- and Naip5-Mediated Macrophage Immunity , 2006, PLoS pathogens.
[58] Milton W. Taylor,et al. Global transcriptional profiling demonstrates the combination of type I and type II interferon enhances antiviral and immune responses at clinically relevant doses. , 2005, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
[59] T. Decker,et al. The Yin and Yang of type I interferon activity in bacterial infection , 2005, Nature Reviews Immunology.
[60] S. Akira,et al. Differential Roles of Toll-Like Receptors 2 and 4 in In Vitro Responses of Macrophages to Legionella pneumophila , 2005, Infection and Immunity.
[61] R. Isberg,et al. Macrophages from Mice with the Restrictive Lgn1 Allele Exhibit Multifactorial Resistance to Legionella pneumophila , 2004, Infection and Immunity.
[62] F. Fang. Antimicrobial reactive oxygen and nitrogen species: concepts and controversies , 2004, Nature Reviews Microbiology.
[63] A. Abadie,et al. Type I interferon and TNFα cooperate with type II interferon for TRAIL induction and triggering of apoptosis in SK-N-MC EWING tumor cells , 2004, Oncogene.
[64] T. Maniatis,et al. IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[65] M. Hensel,et al. Inducible nitric oxide synthase and control of intracellular bacterial pathogens. , 2003, Microbes and infection.
[66] T. Maniatis,et al. IKKε and TBK1 are essential components of the IRF3 signaling pathway , 2003, Nature Immunology.
[67] J. Hiscott,et al. Identification of the Minimal Phosphoacceptor Site Required for in Vivo Activation of Interferon Regulatory Factor 3 in Response to Virus and Double-stranded RNA* , 2003, The Journal of Biological Chemistry.
[68] D. Creely,et al. IKK-i and TBK-1 are Enzymatically Distinct from the Homologous Enzyme IKK-2 , 2002, The Journal of Biological Chemistry.
[69] S. Akira,et al. Lipopolysaccharide Stimulates the MyD88-Independent Pathway and Results in Activation of IFN-Regulatory Factor 3 and the Expression of a Subset of Lipopolysaccharide-Inducible Genes1 , 2001, The Journal of Immunology.
[70] G. Stark,et al. Roles of Phosphatidylinositol 3-Kinase in Interferon-γ-dependent Phosphorylation of STAT1 on Serine 727 and Activation of Gene Expression* , 2001, The Journal of Biological Chemistry.
[71] V. Bach,et al. Induction of iNOS in human monocytes infected with different Legionella species. , 2001, FEMS microbiology letters.
[72] T. Taniguchi,et al. Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains. , 2000, Science.
[73] D. Hume,et al. IFN-gamma primes macrophage responses to bacterial DNA. , 1998, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
[74] T. Decker,et al. GAS elements: a few nucleotides with a major impact on cytokine-induced gene expression. , 1997, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.
[75] J. Brieland,et al. Effector mechanisms responsible for gamma interferon-mediated host resistance to Legionella pneumophila lung infection: the role of endogenous nitric oxide differs in susceptible and resistant murine hosts , 1996, Infection and immunity.
[76] H. Murray. Current and future clinical applications of interferon-gamma in host antimicrobial defense , 1996, Intensive Care Medicine.
[77] J. Aliberti,et al. Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages , 1995, Infection and immunity.
[78] C. Newton,et al. Inhibition of Legionella pneumophila growth by gamma interferon in permissive A/J mouse macrophages: role of reactive oxygen species, nitric oxide, tryptophan, and iron(III) , 1994, Infection and immunity.
[79] A. Sher,et al. The microbicidal activity of interferon‐γ‐treated macrophages against Trypanosoma cruzi involves an L‐arginine‐dependent, nitrogen oxide‐mediated mechanism inhibitable by interleukin‐10 and transforming growth factor‐β , 1992, European journal of immunology.
[80] M. Fresno,et al. Synergism between tumor necrosis factor‐α and interferon‐γ on macrophage activation for the killing of intracellular Trypanosoma cruzi through a nitric oxide‐dependent mechanism , 1992 .
[81] C. Nathan,et al. Agonist and antagonist effects of interferon alpha and beta on activation of human macrophages. Two classes of interferon gamma receptors and blockade of the high-affinity sites by interferon alpha or beta , 1988, The Journal of experimental medicine.
[82] R. Germain,et al. Induction of macrophage Ia antigen expression by rIFN-gamma and down-regulation by IFN-alpha/beta and dexamethasone are mediated by changes in steady-state levels of Ia mRNA. , 1987, Journal of immunology.
[83] B. Zingales,et al. Cell surface antigens of Trypanosoma cruzi: possible correlation with the interiorization process in mammalian cells. , 1982, Molecular and biochemical parasitology.
[84] W. Kaiser,et al. Receptor-Interacting Protein Homotypic Interaction Motif-Dependent Control of NF- B Activation via the DNA-Dependent Activator of IFN Regulatory Factors , 2008 .
[85] R. Medzhitov,et al. Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. , 2006, Immunity.
[86] C. Nathan,et al. Nitric oxide and macrophage function. , 1997, Annual review of immunology.
[87] M. Fresno,et al. Synergism between tumor necrosis factor-alpha and interferon-gamma on macrophage activation for the killing of intracellular Trypanosoma cruzi through a nitric oxide-dependent mechanism. , 1992, European journal of immunology.