The Oxford modular cataract image analysis system

A modular system of acquisition and analysis of Scheimpflug, retro-illumination and fluorescence images of the in vivo human crystalline lens is described. Image analysis is directed towards the following goals: Scheimpflug slit-images are analysed for: (1) The optical density of nuclear cataract present; (2) The dimensions of the lens and the lenticular zones; (3) The curvatures of the lens and lenticular zones.Retro-illumination images are analysed for: (1) The percentage area which is occupied by cataract; (2) A combined measure (weighted integral) describing both the amount of cataract present and its optical density. Lenticular auto-fluorescence images are analysed for the mean density (fluorescence) of the lens as a whole. A pilot study of the repeatability of the methods is presented.

[1]  A. Sommer.  Cataracts as an epidemiologic problem. , 1977, American journal of ophthalmology.

[2]  T. Kawara,et al.  A new method for retroillumination photography of cataractous lens opacities. , 1980, American journal of ophthalmology.

[3]  T. Dawber,et al.  The Framingham Eye Study monograph: An ophthalmological and epidemiological study of cataract, glaucoma, diabetic retinopathy, macular degeneration, and visual acuity in a general population of 2631 adults, 1973-1975. , 1980, Survey of ophthalmology.

[4]  N A Brown,et al.  The Oxford retro-illumination cataract recording camera--a new instrument. , 1988, The Journal of audiovisual media in medicine.

[5]  L. Chylack,et al.  Classification of human senile cataractous changes by the American Cooperative Cataract Research Group (CCRG) method. I. Instrumentation and technique. , 1983, Investigative ophthalmology & visual science.

[6]  S. Lerman,et al.  Ultraviolet-visible slit lamp densitography of the human eye. , 1981, Experimental eye research.

[7]  N. Brown.  Slit-image photography. , 1970, Transactions of the ophthalmological societies of the United Kingdom.

[8]  N. Brown.  Quantitative slit-image photography of the lens. , 1972, Transactions of the ophthalmological societies of the United Kingdom.

[9]  N. Brown,et al.  Dynamic nature of posterior subcapsular cataract. , 1989, The British journal of ophthalmology.

[10]  N. Brown.  An advanced slit-image camera. , 1972, The British journal of ophthalmology.

[11]  L T Chylack,et al.  Sources of variance in the objective documentation of human cataractous change with Topcon SL-45 and Neitz-CTR retroillumination photography and computerized image analysis. , 1987, Current eye research.

[12]  Standardizing Diagnostic Procedures , 1975 .

[13]  J. Whelan,et al.  Human cataract formation. , 1984, Ciba Foundation symposium.

[14]  C J Taylor,et al.  An objective staging for cortical cataract in vivo aided by pattern-analysing computer. , 1981, Experimental eye research.

[15]  George Duncan,et al.  Mechanisms of cataract formation in the human lens , 1981 .

[16]  Nicholas A P Brown,et al.  The objective assessment of cataract , 1987, Eye.

[17]  K. Sasaki,et al.  In vivo color analysis of human crystalline lenses. , 1985, Ophthalmic research.

[18]  Keith J. Hanna,et al.  Tracking cataract by the "four-line" method , 1989, Image Vis. Comput..

[19]  M. C. Leske,et al.  The epidemiology of senile cataracts: a review. , 1983, American journal of epidemiology.

[20]  H. Nieminen,et al.  Autofluorescence of the human diabetic lens in vivo. , 1976, American journal of ophthalmology.