Signaling cross-talk between hypoxia and glucose via hypoxia-inducible factor 1 and glucose response elements.

[1]  Saroj P. Mathupala,et al.  Glucose Catabolism in Cancer Cells , 2001, The Journal of Biological Chemistry.

[2]  K. Uyeda,et al.  Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[3]  Michael I. Wilson,et al.  C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation , 2001, Cell.

[4]  Yukihiro Kondo,et al.  Expression and Characterization of Hypoxia-Inducible Factor (HIF)-3α in Human Kidney: Suppression of HIF-Mediated Gene Expression by HIF-3α , 2001 .

[5]  K. Jungermann,et al.  Cross-talk between the signals hypoxia and glucose at the glucose response element of the L-type pyruvate kinase gene. , 2001, Endocrinology.

[6]  G. Semenza Hypoxia-Inducible Factor 1: Control of Oxygen Homeostasis in Health and Disease , 2001, Pediatric Research.

[7]  K. Jungermann,et al.  Perivenous expression of the mRNA of the three hypoxia-inducible factor alpha-subunits, HIF1alpha, HIF2alpha and HIF3alpha, in rat liver. , 2001, The Biochemical journal.

[8]  M. Vasseur-Cognet,et al.  Glucose Regulation of Gene Transcription* , 2000, The Journal of Biological Chemistry.

[9]  K. Kim,et al.  Nutritional regulation of the fatty acid synthase promoter in vivo: sterol regulatory element binding protein functions through an upstream region containing a sterol regulatory element. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[10]  G. Semenza,et al.  HIF-1 and human disease: one highly involved factor. , 2000, Genes & development.

[11]  T. Kietzmann,et al.  Oxygen Radicals as Messengers in Oxygen-Dependent Gene Expression. , 2000, News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society.

[12]  K. Jungermann,et al.  Perivenous localization of insulin receptor protein in rat liver, and regulation of its expression by glucose and oxygen in hepatocyte cultures. , 2000, The Biochemical journal.

[13]  G. Semenza HIF-1: mediator of physiological and pathophysiological responses to hypoxia. , 2000, Journal of applied physiology.

[14]  K. Jungermann,et al.  Oxygen: Modulator of metabolic zonation and disease of the liver , 2000, Hepatology.

[15]  P. Carmeliet,et al.  correction: Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis , 1998, Nature.

[16]  S. Vaulont,et al.  Differential Roles of Upstream Stimulatory Factors 1 and 2 in the Transcriptional Response of Liver Genes to Glucose* , 1998, The Journal of Biological Chemistry.

[17]  Jessica Lo,et al.  HIF‐1α is required for solid tumor formation and embryonic vascularization , 1998 .

[18]  K. Jungermann,et al.  Periportal localization of glucagon receptor mRNA in rat liver and regulation of its expression by glucose and oxygen in hepatocyte cultures , 1998, FEBS letters.

[19]  S. Vaulont,et al.  Glucose-dependent Liver Gene Expression in Upstream Stimulatory Factor 2 −/− Mice* , 1997, The Journal of Biological Chemistry.

[20]  F. Gaunitz,et al.  Cell-cell interactions in the regulation of the expression of hepatic enzymes , 1997, Cell Biology and Toxicology.

[21]  M. Gassmann,et al.  Oxygen(es) and the hypoxia-inducible factor-1. , 1997, Biological chemistry.

[22]  Y Fujii-Kuriyama,et al.  A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[23]  W. Risau,et al.  HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1α and developmentally expressed in blood vessels , 1997, Mechanisms of Development.

[24]  J. Hogenesch,et al.  Characterization of a Subset of the Basic-Helix-Loop-Helix-PAS Superfamily That Interacts with Components of the Dioxin Signaling Pathway* , 1997, The Journal of Biological Chemistry.

[25]  A. Kahn Transcriptional regulation by glucose in the liver. , 1997, Biochimie.

[26]  R. O. Poyton,et al.  Oxygen sensing and molecular adaptation to hypoxia. , 1996, Physiological reviews.

[27]  K. Jungermann,et al.  Regulation of the gluconeogenic phosphoenolpyruvate carboxykinase and the glycolytic aldolase A gene expression by O2 in rat hepatocyte cultures. Involvement of hydrogen peroxide as mediator in the response to O2 , 1996, FEBS letters.

[28]  H. Towle Metabolic Regulation of Gene Transcription in Mammals (*) , 1995, The Journal of Biological Chemistry.

[29]  G. Semenza,et al.  Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[30]  B. Ebert,et al.  Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[31]  H. Shih,et al.  Definition of the carbohydrate response element of the rat S14 gene. Context of the CACGTG motif determines the specificity of carbohydrate regulation. , 1994, The Journal of biological chemistry.

[32]  K. Jungermann,et al.  A ferro-heme protein senses oxygen levels, which modulate the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene in rat hepatocyte cultures. , 1993, Biochemical and biophysical research communications.

[33]  H. Shih,et al.  Definition of the carbohydrate response element of the rat S14 gene. Evidence for a common factor required for carbohydrate regulation of hepatic genes. , 1992, The Journal of biological chemistry.

[34]  T. Noguchi,et al.  Molecular Mechanism of Induction of Key Enzymes Related to Lipogenesis , 1992, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[35]  M. Díaz-Guerra,et al.  Cis-regulation of the L-type pyruvate kinase gene promoter by glucose, insulin and cyclic AMP. , 1992, Nucleic acids research.

[36]  K. Jungermann,et al.  Modulation by oxygen of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene in rat hepatocyte cultures. , 1991, European journal of biochemistry.

[37]  O. Hankinson,et al.  Cloning of a factor required for activity of the Ah (dioxin) receptor. , 1991, Science.

[38]  R. Roeder,et al.  The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. , 1990, Genes & development.

[39]  S. Vaulont,et al.  Proteins binding to the liver-specific pyruvate kinase gene promoter. A unique combination of known factors. , 1989, Journal of molecular biology.

[40]  K. Jungermann,et al.  Functional specialization of different hepatocyte populations. , 1989, Physiological reviews.

[41]  M. Goldberg,et al.  Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein. , 1988, Science.

[42]  T. Noguchi,et al.  Nutrient and hormonal regulation of pyruvate kinase gene expression. , 1999, The Biochemical journal.

[43]  G. Semenza,et al.  Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. , 1999, Annual review of cell and developmental biology.

[44]  L. Wartman,et al.  Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha. , 1998, Gene expression.

[45]  K. Jungermann,et al.  Arterial oxygen partial pressures reduce the insulin-dependent induction of the perivenously located glucokinase in rat hepatocyte cultures: mimicry of arterial oxygen pressures by H2O2. , 1997, The Biochemical journal.

[46]  J. Girard,et al.  Mechanisms by which carbohydrates regulate expression of genes for glycolytic and lipogenic enzymes. , 1997, Annual review of nutrition.

[47]  S. McKnight,et al.  Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. , 1997, Genes & development.

[48]  K. Jungermann,et al.  Zonation of parenchymal and nonparenchymal metabolism in liver. , 1996, Annual review of nutrition.

[49]  M. Gassmann,et al.  The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1) DNA recognition site. , 1995, Nucleic acids research.

[50]  A. Moorman,et al.  Hepatocyte heterogeneity in the metabolism of amino acids and ammonia. , 1992, Enzyme.

[51]  K. Jungermann,et al.  Distribution of pyruvate kinase type L and M2 in microdissected periportal and perivenous rat liver tissue with different dietary states. , 1983, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.