K-ras mutations and allelic loss at 5q and 18q in the development of human pancreatic cancers

[1]  C. Moskaluk,et al.  Homozygous deletion map at 18q21.1 in pancreatic cancer. , 1996, Cancer research.

[2]  Scott E. Kern,et al.  DPC4, A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1 , 1996, Science.

[3]  Y. Shiratori,et al.  Analysis of K-ras gene mutation in hyperplastic duct cells of the pancreas without pancreatic disease. , 1996, Gastroenterology.

[4]  J. Minna,et al.  Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma. , 1995, JAMA.

[5]  A. Gazdar,et al.  K-ras mutations are a relatively late event in the pathogenesis of lung carcinomas. , 1994, Cancer research.

[6]  R. Hruban,et al.  Detection of K-ras mutations in the stool of patients with pancreatic adenocarcinoma and pancreatic ductal hyperplasia. , 1994, Cancer research.

[7]  C Caldas,et al.  Allelotype of pancreatic adenocarcinoma. , 1994, Cancer research.

[8]  J. Cameron,et al.  Detection of K-ras mutations in mucinous pancreatic duct hyperplasia from a patient with a family history of pancreatic carcinoma. , 1994, The American journal of pathology.

[9]  H. Adami,et al.  Pancreatitis and pancreatic cancer: a population-based study. , 1994, Journal of the National Cancer Institute.

[10]  D. Shibata,et al.  Early mutational activation of the c-Ki-ras oncogene in endometrial carcinoma. , 1994, Cancer research.

[11]  N. Pellegata,et al.  K-ras and p53 gene mutations in pancreatic cancer: ductal and nonductal tumors progress through different genetic lesions. , 1994, Cancer research.

[12]  S. Maeda,et al.  The role ofras mutation in pancreatic cancer, precancerous lesions, and chronic pancreatitis , 1993 .

[13]  J. Bernaudin,et al.  Detection of c-Ki-ras mutation by PCR/RFLP analysis and diagnosis of pancreatic adenocarcinomas. , 1993, Journal of the National Cancer Institute.

[14]  N. Lemoine,et al.  Abnormalities affecting the APC and MCC tumour suppressor gene loci on chromosome 5q occur frequently in gastric cancer but not in pancreatic cancer , 1993, International journal of cancer.

[15]  S. Goodman,et al.  K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization. , 1993, The American journal of pathology.

[16]  J. Bishop,et al.  Predisposition to neoplastic transformation caused by gene replacement of H-ras1. , 1993, Science.

[17]  S. Hirohashi,et al.  Pancreatic adenocarcinomas frequently show p53 gene mutations. , 1993, The American journal of pathology.

[18]  A. Berchuck,et al.  Mutation of the Ki-ras protooncogene in human endometrial hyperplasia and carcinoma. , 1993, Cancer research.

[19]  R. Padmanabhan,et al.  K-ras and p53 point mutations in 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced hamster lung tumors. , 1993, Carcinogenesis.

[20]  A. Yanagisawa,et al.  Frequent c-Ki-ras oncogene activation in mucous cell hyperplasias of pancreas suffering from chronic inflammation. , 1993, Cancer research.

[21]  T. Urano,et al.  Detection of point mutations in the Kirsten-ras oncogene provides evidence for the multicentricity of pancreatic carcinoma. , 1993, Annals of surgery.

[22]  M. Leppert,et al.  A CA-repeat polymorphism close to the adenomatous polyposis coli (APC) gene offers improved diagnostic testing for familial APC. , 1993, American journal of human genetics.

[23]  S Ichii,et al.  Frequent somatic mutations of the APC gene in human pancreatic cancer. , 1992, Cancer research.

[24]  N. Nadon,et al.  Polymerase chain reaction microanalysis of tumors from stained histological slides. , 1992, Oncogene.

[25]  J. Boyd,et al.  Dinucleotide repeat polymorphism in the human DCC gene at chromosome 18q21. , 1992, Human molecular genetics.

[26]  Kathleen R. Cho,et al.  Genetic alterations in the adenoma–carcinoma sequence , 1992, Cancer.

[27]  R. Weinel,et al.  Frequent loss of expression of the potential tumor suppressor gene DCC in ductal pancreatic adenocarcinoma. , 1992, Cancer research.

[28]  A. Todd,et al.  Estimation of the proportions of mutant and normal N-ras alleles by allele specific restriction analysis. , 1992, Nucleic acids research.

[29]  N. Lemoine,et al.  Ki-ras oncogene activation in preinvasive pancreatic cancer. , 1992, Gastroenterology.

[30]  K. Kinzler,et al.  Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. , 1991, Science.

[31]  S. Altschul,et al.  Identification of FAP locus genes from chromosome 5q21. , 1991, Science.

[32]  J. Minna,et al.  Mutations of ras genes distinguish a subset of non-small-cell lung cancer cell lines from small-cell lung cancer cell lines. , 1991, Oncogene.

[33]  J. L. Bos,et al.  ras oncogenes in human cancer: a review. , 1989, Cancer research.

[34]  R. Weinberg,et al.  Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis. , 1989, Cancer research.

[35]  J. Guillem,et al.  Rapid detection of ras oncogenes in human tumors: applications to colon, esophageal, and gastric cancer. , 1989, Oncogene.

[36]  C. Bartram,et al.  High frequency of Ki‐ras codon 12 mutations in pancreatic adenocarcinomas , 1989, International journal of cancer.

[37]  Y. Nakamura,et al.  Genetic alterations during colorectal-tumor development. , 1988, The New England journal of medicine.

[38]  D. Shibata,et al.  Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes , 1988, Cell.

[39]  V. Rotter,et al.  Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation , 1984, Nature.

[40]  D. Ilstrup,et al.  Total pancreatectomy for ductal adenocarcinoma of the pancreas. Mayo Clinic experience. , 1981, American journal of surgery.

[41]  S. Saga,et al.  Relation of pancreatic duct hyperplasia to carcinoma , 1979, Cancer.

[42]  S. Bengmark,et al.  Total Pancreatectomy for Cancer An appraisal of 65 cases , 1977, Annals of surgery.

[43]  D. Slaughter,et al.  “Field cancerization” in oral stratified squamous epithelium. Clinical implications of multicentric origin , 1953, Cancer.